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18 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Similarity- and Substructure-Based Development ofßEBI
Philipps University Marburg
First Structure-Activity Relationship of 17ß-Hydroxysteroid Dehydrogenase Type 14 Nonsteroidal Inhibitors and Crystal Structures in Complex with the Enzyme.EBI
Philipps University Marburg
New Insights into Human 17ß-Hydroxysteroid Dehydrogenase Type 14: First Crystal Structures in Complex with a Steroidal Ligand and with a Potent Nonsteroidal Inhibitor.EBI
Philipps University Marburg
Fragment Binding Can Be Either More Enthalpy-Driven or Entropy-Driven: Crystal Structures and Residual Hydration Patterns Suggest Why.EBI
Philipps University Marburg
Development of new cyclic plasmin inhibitors with excellent potency and selectivity.EBI
Philipps University Marburg
Ligand binding stepwise disrupts water network in thrombin: enthalpic and entropic changes reveal classical hydrophobic effect.EBI
Philipps University Marburg
A new strategy for the development of highly potent and selective plasmin inhibitors.EBI
Philipps University Marburg
New substrate analogue furin inhibitors derived from 4-amidinobenzylamide.EBI
Philipps University Marburg
Development of substrate analogue inhibitors for the human airway trypsin-like protease HAT.EBI
Philipps University Marburg
New furin inhibitors based on weakly basic amidinohydrazones.EBI
Philipps University Marburg
Potent inhibitors of furin and furin-like proprotein convertases containing decarboxylated P1 arginine mimetics.EBI
Philipps University Marburg
Optimization of Cyclic Plasmin Inhibitors: From Benzamidines to Benzylamines.EBI
Philipps University Marburg
Fibrinolysis Inhibitors: Potential Drugs for the Treatment and Prevention of Bleeding.EBI
Philipps University Marburg
Inhibiting Hedgehog: An Update on Pharmacological Compounds and Targeting Strategies.EBI
Philipps University Marburg
Structure-based design and profiling of novel 17β-HSD14 inhibitors.EBI
Philipps University Marburg
Thiazole orexin receptor antagonistsBDB
Merck Sharp & Dohme
Discovery of (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3-[2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (SCH 503034), a selective, potent, orally bioavailable hepatitis C virus NS3 protease inhibitorBDB
Schering-Plough Research Institute
Novel isoindoline compounds for potent and selective inhibition of prolyl dipeptidase DPP8.BDB
National Health Research Institutes