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A new approach to the design of sigma-2-selective ligands: synthesis and evaluation of N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-2-(1- pyrrolidinyl)ethylamine-related polyamines at sigma-1 and sigma-2 receptor subtypes.

National Institutes of Diabetes and Digestive and Kidney Diseases

Structure-activity relationship of (N)-Methanocarba phosphonate analogues of 5'-AMP as cardioprotective agents acting through a cardiac P2X receptor.

National Institutes of Diabetes and Digestive and Kidney Diseases

Probing the elusive catalytic activity of vertebrate class IIa histone deacetylases.

Irbm/Merck Research Laboratories