PMID

Data

Article Title

Organization

Discovery, optimization, and characterization of novel D2 dopamine receptor selective antagonists.

National Center For Advancing Translational Sciences

Identification of ML251, a Potent Inhibitor of T. brucei and T. cruzi Phosphofructokinase.

National Center For Advancing Translational Sciences

Structure-activity relationship studies and biological characterization of human NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors.

National Center For Advancing Translational Sciences

Synthesis and SAR studies of 5-(pyridin-4-yl)-1,3,4-thiadiazol-2-amine derivatives as potent inhibitors of Bloom helicase.

National Center For Advancing Translational Sciences

Synthesis and biological evaluation of analogues of the kinase inhibitor nilotinib as Abl and Kit inhibitors.

National Center For Advancing Translational Sciences

Discovery of a novel noniminosugar acida glucosidase chaperone series.

National Center For Advancing Translational Sciences

Synthesis, biological evaluation, and structure-activity relationships of a novel class of apurinic/apyrimidinic endonuclease 1 inhibitors.

National Center For Advancing Translational Sciences

Structure-Based Optimization of Small Molecule Human Galactokinase Inhibitors.

National Center For Advancing Translational Sciences

Discovery and Optimization of 2

National Center For Advancing Translational Sciences

Design, Synthesis, and Biological Evaluation of Quinazolin-4-one-Based Hydroxamic Acids as Dual PI3K/HDAC Inhibitors.

National Center For Advancing Translational Sciences

Synthesis and structure-activity relationship studies of N-benzyl-2-phenylpyrimidin-4-amine derivatives as potent USP1/UAF1 deubiquitinase inhibitors with anticancer activity against nonsmall cell lung cancer.

National Center For Advancing Translational Sciences

Discovery of 3-(4-sulfamoylnaphthyl)pyrazolo[1,5-a]pyrimidines as potent and selective ALK2 inhibitors.

National Center For Advancing Translational Sciences

Discovery of Orally Bioavailable, Quinoline-Based Aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitors with Potent Cellular Activity.

National Center For Advancing Translational Sciences

Optimization of the first small-molecule relaxin/insulin-like family peptide receptor (RXFP1) agonists: Activation results in an antifibrotic gene expression profile.

National Center For Advancing Translational Sciences

Discovery and optimization of piperazine-1-thiourea-based human phosphoglycerate dehydrogenase inhibitors.

National Center For Advancing Translational Sciences

Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH).

National Center For Advancing Translational Sciences