PMID

Data

Article Title

Organization

alpha,alpha-Cyclic aminoacids as useful scaffolds for the preparation of hNK(2) receptor antagonists.

Menarini Ricerche

Design and synthesis of novel sulfonamide-containing bradykinin hB(2) receptor antagonists. Synthesis and structure-relationships ofa,a-tetrahydropyranylglycine.

Menarini Ricerche

hNK2 receptor antagonists. The use of intramolecular hydrogen bonding to increase solubility and membrane permeability.

Menarini Ricerche

Structure-activity relationships of 6-methyl-benzo[b]thiophene-2-carboxylic acid (1-[(S)-1-benzyl-4-[4-(tetrahydropyran-4-ylmethyl)piperazin-1-yl]butylcarbamoyl]cyclopentyl)amide, potent antagonist of the neurokinin-2 receptor.

Menarini Ricerche

Cinnamic acids and mono-substituted benzoic acids as useful capping groups for the preparation of hNK2 receptor antagonists.

Menarini Ricerche

Histone deacetylase inhibitors: from bench to clinic.

Menarini Ricerche

Generation of a new class of hNK(2) receptor ligands using the 'fragment approach'.

Menarini Ricerche

1,2-disubstituted cyclohexane derived tripeptide aldehydes as novel selective thrombin inhibitors.

Menarini Ricerche

Benzofused hydroxamic acids: useful fragments for the preparation of histone deacetylase inhibitors. Part 1: hit identification.

Menarini Ricerche

Antiproliferative and differentiating activities of a novel series of histone deacetylase inhibitors.

Menarini Ricerche

Discovery of a new series of potent and selective linear tachykinin NK2 receptor antagonists.

Menarini Ricerche

Insertion of an aspartic acid moiety into cyclic pseudopeptides: synthesis and biological characterization of potent antagonists for the human Tachykinin NK-2 receptor.

Menarini Ricerche

Monocyclic human tachykinin NK-2 receptor antagonists as evolution of a potent bicyclic antagonist: QSAR and site-directed mutagenesis studies.

Menarini Ricerche

Discovery of potent cyclic pseudopeptide human tachykinin NK-2 receptor antagonists.

Menarini Ricerche