PMID

Data

Article Title

Organization

Chemistry and biology of the 2 beta-alkyl-3 beta-phenyl analogues of cocaine: subnanomolar affinity ligands that suggest a new pharmacophore model at the C-2 position.

Mayo Foundation

The novel Ins(1,4,5)P3 analogue 3-amino-3-deoxy-Ins(1,4,5)P3: a pH-dependent Ins(1,4,5)P3 receptor partial agonist in SH-SY5Y neuroblastoma cells.

Mayo Foundation

Deoxygenated inositol 1,4,5-trisphosphate analogues and their interaction with metabolic enzymes. (1R,2R,4R)-cyclohexane-1,2,4-tris(methylenesulfonate): a potent selective 5-phosphatase inhibitor.

Mayo Foundation

Structure-activity relationship studies of cocaine: replacement of the C-2 ester group by vinyl argues against H-bonding and provides an esterase-resistant, high-affinity cocaine analogue.

Mayo Foundation

Chemistry, binding affinities, and behavioral properties of a new class of"antineophobic" mitochondrial DBI receptor complex (mDRC) ligands.

Mayo Foundation

Urea derivatives and uses thereof

Kala Pharmaceuticals

Bicyclic heterocyclic compounds as PDE2 inhibitors

Merck Sharp & Dohme

Pyridine derivative

Astellas Pharma

Synthesis and anticholinesterase activities of novel 1,3,4-thiadiazole based compounds.

University of Life Sciences

Prolylcarboxypeptidase inhibitors

Merck Sharp & Dohme

5-(1H-Benzimidazol-1-yl)-3-alkoxy-2-thiophenecarbonitriles as potent, selective, inhibitors of IKK-epsilon kinase.

Gsk