34 articles for thisTarget
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Physapubescin, a natural withanolide as a kidney-type glutaminase (KGA) inhibitor.
Huazhong University of Science and Technology
Amaryllidaceae alkaloids with new framework types from Zephyranthes candida as potent acetylcholinesterase inhibitors.
Huazhong University of Science and Technology
Synthesis and biological evaluation of new 6-hydroxypyridazinone benzisoxazoles: Potential multi-receptor-targeting atypical antipsychotics.
Huazhong University of Science and Technology
Synthesis and Biological Evaluation of Novels1 Receptor Ligands for Treating Neuropathic Pain: 6-Hydroxypyridazinones.
Huazhong University of Science and Technology
Synthesis and pharmacological evaluation of piperidine (piperazine)-substituted benzoxazole derivatives as multi-target antipsychotics.
Huazhong University of Science and Technology
Synthesis and biological evaluation of novel sigma-1 receptor antagonists based on pyrimidine scaffold as agents for treating neuropathic pain.
Huazhong University of Science and Technology
Synthesis and biological evaluation of a series of benzoxazole/benzothiazole-containing 2,3-dihydrobenzo[b][1,4]dioxine derivatives as potential antidepressants.
Huazhong University of Science and Technology
Synthesis and biological evaluation of a novel sigma-1 receptor antagonist based on 3,4-dihydro-2(1H)-quinolinone scaffold as a potential analgesic.
Huazhong University of Science and Technology
Synthesis and evaluation of new coumarin derivatives as potential atypical antipsychotics.
Huazhong University of Science and Technology
Synthesis and biological investigation of coumarin piperazine (piperidine) derivatives as potential multireceptor atypical antipsychotics.
Huazhong University of Science and Technology
Effect of daurisoline on HERG channel electrophysiological function and protein expression.
Huazhong University of Science and Technology
Novel multipotent phenylthiazole-tacrine hybrids for the inhibition of cholinesterase activity,ß-amyloid aggregation and Ca²¿ overload.
Huazhong University of Science and Technology
Multifunctional mercapto-tacrine derivatives for treatment of age-related neurodegenerative diseases.
Huazhong University of Science and Technology
Synthesis and antimicrobial activity of N¹-benzyl or N¹-benzyloxy-1,6-dihydro-1,3,5-triazine-2,4-diamines.
Huazhong University of Science and Technology
Inactivation of GABA transaminase by 3-chloro-1-(4-hydroxyphenyl)propan-1-one.
Huazhong University of Science and Technology
Design, synthesis, and cytoprotective effect of 2-aminothiazole analogues as potent poly(ADP-ribose) polymerase-1 inhibitors.
Huazhong University of Science and Technology
Transient Receptor Potential Melastatin 7 (TRPM7) Ion Channel Inhibitors: Preliminary SAR and Conformational Studies of Xenicane Diterpenoids from the Hawaiian Soft Coral
Huazhong University of Science and Technology
Diaporaustalides A-L, Austalide Meroterpenoids from a Plant Endophytic
Huazhong University of Science and Technology
Inhibition of GABA shunt enzymes' activity by 4-hydroxybenzaldehyde derivatives.
Huazhong University of Science and Technology
Jatrophane Diterpenoids with Kv1.3 Ion Channel Inhibitory Effects from
Huazhong University of Science and Technology
Rational Design and Synthesis of Novel Dual PROTACs for Simultaneous Degradation of EGFR and PARP.
Huazhong University of Science and Technology
Optimization of bifunctional piperidinamide derivatives as σ
Huazhong University of Science and Technology
Discovery of a new class of multi-target heterocycle piperidine derivatives as potential antipsychotics with pro-cognitive effect.
Huazhong University of Science and Technology
Piperidine propionamide as a scaffold for potent sigma-1 receptor antagonists and mu opioid receptor agonists for treating neuropathic pain.
Huazhong University of Science and Technology
Discovery of an Orally Active Small-Molecule Tumor Necrosis Factor-α Inhibitor.
Huazhong University of Science and Technology
Galanthamine, Plicamine, and Secoplicamine Alkaloids from Zephyranthes candida and Their Anti-acetylcholinesterase and Anti-inflammatory Activities.
Huazhong University of Science and Technology
Bipolaricins A-I, Ophiobolin-Type Tetracyclic Sesterterpenes from a Phytopathogenic
Huazhong University of Science and Technology
Flavipesines A and B and Asperchalasines E-H: Cytochalasans and Merocytochalasans from
Huazhong University of Science and Technology
Synthesis and Biological Evaluation of Fused Tricyclic Heterocycle Piperazine (Piperidine) Derivatives As Potential Multireceptor Atypical Antipsychotics.
Huazhong University of Science and Technology
BACE1 Inhibitory Meroterpenoids from Aspergillus terreus.
Huazhong University of Science and Technology
Acetylcholinesterase Inhibitory Alkaloids from the Whole Plants of Zephyranthes carinata.
Huazhong University of Science and Technology
