PMID

Data

Article Title

Organization

The discovery of a potent, intracellular, orally bioavailable, long duration inhibitor of human neutrophil elastase--GW311616A a development candidate.

Glaxowellcome Medicines Research Centre

Sialidase inhibitors related to zanamivir. Further SAR studies of 4-amino-4H-pyran-2-carboxylic acid-6-propylamides.

Glaxowellcome Medicines Research Centre

Intracellular inhibition of human neutrophil elastase by orally active pyrrolidine-trans-lactams.

Glaxowellcome Medicines Research Centre

The discovery and synthesis of highly potent, A2a receptor agonists.

Glaxowellcome Medicines Research Centre

2-chloro-3-substituted-1,4-naphthoquinone inactivators of human cytomegalovirus protease.

Glaxowellcome Medicines Research Centre

Syntheses of trans-5-oxo-hexahydro-pyrrolo[3,2-b]pyrroles and trans-5-oxo-hexahydro-furo[3,2-b]pyrroles (pyrrolidine trans-lactams and trans-lactones): new pharmacophores for elastase inhibition.

Glaxowellcome Medicines Research Centre