PMID

Data

Article Title

Organization

Identification of a novel Smoothened antagonist that potently suppresses Hedgehog signaling.

Duke University Medical Center

Stapled peptides as scaffolds for developing radiotracers for intracellular targets: Preliminary evaluation of a radioiodinated MDM2-binding stapled peptide in the SJSA-1 osteosarcoma model.

Duke University Medical Center

Betulinic acid derivatives that target gp120 and inhibit multiple genetic subtypes of human immunodeficiency virus type 1.

Duke University Medical Center

Structure of the deacetylase LpxC bound to the antibiotic CHIR-090: Time-dependent inhibition and specificity in ligand binding.

Duke University Medical Center

Elimination of HIV-1 Latently Infected Cells by Gnidimacrin and a Selective HDAC Inhibitor.

Duke University Medical Center

Phthalazinones and isoquinolinones as rock inhibitors

Bristol-Myers Squibb

Pyrazolopyrimidinyl inhibitors of ubiquitin-activating enzyme

Millennium Pharmaceuticals

Rational design of 4,5-disubstituted-5,7-dihydro-pyrrolo[2,3-d]pyrimidin-6-ones as a novel class of inhibitors of epidermal growth factor receptor (EGF-R) and Her2(p185(erbB)) tyrosine kinases.

Sugen