Compile Data Set for Download or QSAR
Report error Found 15 of affinity data for UniProtKB/TrEMBL: Q9WV60
TargetGlycogen synthase kinase-3 beta(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50325986(3-(6-(3-aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of GSK-3 beta in mouse D3 cells assessed as induction of neuron specific marker neurofilament-M by immunofluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50325986(3-(6-(3-aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-...)
Affinity DataKd:  126nMAssay Description:Inhibition of GSK-3 beta in mouse D3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50325986(3-(6-(3-aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of GSK-3 beta in mouse D3 cells assessed as induction of neuron specific marker beta3-tubulin by immunofluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50325986(3-(6-(3-aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of GSK-3 beta in mouse D3 cells assessed as induction of neuron specific marker neurofilament-M by immunofluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50397748(CHEMBL2177155)
Affinity DataIC50: 5nMAssay Description:Inhibition of GSK3beta-mediated Tau phosphorylation in mouse 3T3 cells after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50397743(CHEMBL2177165)
Affinity DataIC50: 10nMAssay Description:Inhibition of GSK3beta-mediated Tau phosphorylation in mouse 3T3 cells after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50397749(CHEMBL2182002)
Affinity DataIC50: 11nMAssay Description:Inhibition of GSK3beta-mediated Tau phosphorylation in mouse 3T3 cells after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50325986(3-(6-(3-aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-...)
Affinity DataIC50: 30nMAssay Description:Binding affinity to GSK-3 beta in mouse D3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50397742(CHEMBL2177166)
Affinity DataIC50: 37nMAssay Description:Inhibition of GSK3beta-mediated Tau phosphorylation in mouse 3T3 cells after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50397741(CHEMBL2177167)
Affinity DataIC50: 47nMAssay Description:Inhibition of GSK3beta-mediated Tau phosphorylation in mouse 3T3 cells after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50397747(CHEMBL2177157)
Affinity DataIC50: 49nMAssay Description:Inhibition of GSK3beta-mediated Tau phosphorylation in mouse 3T3 cells after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50397745(CHEMBL2177161)
Affinity DataIC50: 76nMAssay Description:Inhibition of GSK3beta-mediated Tau phosphorylation in mouse 3T3 cells after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50397746(CHEMBL2177159)
Affinity DataIC50: 79nMAssay Description:Inhibition of GSK3beta-mediated Tau phosphorylation in mouse 3T3 cells after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50397744(CHEMBL2177163)
Affinity DataIC50: 87nMAssay Description:Inhibition of GSK3beta-mediated Tau phosphorylation in mouse 3T3 cells after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50229962(N-(4-METHOXYBENZYL)-N'-(5-NITRO-1,3-THIAZOL-2-YL)U...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human GSK-3beta in mouse 3T3 fibroblasts stably expressing four-repeat tau protein assessed as reduction in tau S396 phosphorylation af...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)