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TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606633(CHEMBL5219936)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606639(CHEMBL5219016)
Affinity DataIC50: 0.260nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606640(CHEMBL5220467)
Affinity DataIC50: 0.340nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606641(CHEMBL5219752)
Affinity DataIC50: 0.360nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606645(CHEMBL5220455)
Affinity DataIC50: 0.390nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606638(CHEMBL5220113)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50581244(CHEMBL5086734)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-e...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606644(CHEMBL5219791)
Affinity DataIC50: 0.510nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50339937(1,1',1''-(5,5',5''-(benzene-1,3,5-triyl)tris(penta...)
Affinity DataIC50: 0.560nMAssay Description:Antagonist activity at alpha9/alpha10 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiolog...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50581248(CHEMBL5090753)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-e...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606650(CHEMBL5219058)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606637(CHEMBL5220002)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50544003(CHEMBL4647678)
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response measured after 5 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50581243(CHEMBL5089881)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-e...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50589246(CHEMBL5184316)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human nAChR alpha9alpha10 expressed in Xenopus laevis oocytes holding potential of -70 mV by voltage-clamp based electrophysiological m...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50339933(1,1',1'',1'''-(5,5',5'',5'''-(benzene-1,2,4,5-tetr...)
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at alpha9/alpha10 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiolog...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50514668(CHEMBL4526368)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-evoked currents by two-electrode voltage cl...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606643(CHEMBL5218653)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50581249(CHEMBL5073182)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-e...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50597506(CHEMBL5190813)
Affinity DataIC50: 2.90nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50597504(CHEMBL5177606)
Affinity DataIC50: 3nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50597507(CHEMBL5176101)
Affinity DataIC50: 3.10nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50544009(CHEMBL4644407)
Affinity DataIC50: 3.40nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response measured after 5 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50339936(2,2',2''-(5,5',5''-(benzene-1,3,5-triyl)tris(penta...)
Affinity DataIC50: 3.70nMAssay Description:Antagonist activity at alpha9/alpha10 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiolog...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606642(CHEMBL5220060)
Affinity DataIC50: 4nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50601896(CHEMBL5203781)
Affinity DataIC50: 4nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 m...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50339934(1,1'-(3,3'-(biphenyl-4,4'-diyl)bis(propane-3,1-diy...)
Affinity DataIC50: 4.20nMAssay Description:Antagonist activity at alpha9/alpha10 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiolog...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50339935(1,1',1''-(5,5',5''-(benzene-1,3,5-triyl)tris(penta...)
Affinity DataIC50: 4.80nMAssay Description:Antagonist activity at alpha9/alpha10 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiolog...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50466607(CHEMBL4293646)
Affinity DataIC50: 4.80nMAssay Description:Antagonist activity at human alpha9alpha10 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50466614(CHEMBL4291079)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at human alpha9alpha10 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50445328(CHEMBL3104241)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of alpha9alpha10 (unknown origin) nAChRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50339938(1,1',1'',1'''-(5,5',5'',5'''-(benzene-1,2,4,5-tetr...)
Affinity DataIC50: 5.40nMAssay Description:Antagonist activity at alpha9/alpha10 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiolog...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50597499(CHEMBL5195695)
Affinity DataIC50: 5.70nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50544008(CHEMBL4634686)
Affinity DataIC50: 5.90nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response measured after 5 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50581246(CHEMBL5080428)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-e...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50597517(CHEMBL5171118)
Affinity DataIC50: 6.30nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50466608(CHEMBL4285772)
Affinity DataIC50: 6.60nMAssay Description:Antagonist activity at human alpha9alpha10 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM80642(CHEMBL191491 | cid_6433339 | MG 624 | MLS002172460...)
Affinity DataIC50: 6.70nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM80642(CHEMBL191491 | cid_6433339 | MG 624 | MLS002172460...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human alpha9alpha10 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50597518(CHEMBL5182114)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50466606(CHEMBL4280452)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at human alpha9alpha10 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50544006(CHEMBL4634288)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response measured after 5 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50339931(1,1'-(3,3'-(biphenyl-4,4'-diyl)bis(prop-2-yne-3,1-...)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at alpha9/alpha10 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiolog...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50466613(CHEMBL4287656)
Affinity DataIC50: 17nMAssay Description:Antagonist activity at human alpha9alpha10 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50597516(CHEMBL5182514)
Affinity DataIC50: 17nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50597505(CHEMBL5174508)
Affinity DataIC50: 18nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50445326(CHEMBL3104239)
Affinity DataIC50: 22nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-evoked currents by two-electrode voltage cl...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606648(CHEMBL5220622)
Affinity DataIC50: 24nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50520486(CHEMBL4460411)
Affinity DataIC50: 33nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50597512(CHEMBL5201239)
Affinity DataIC50: 33nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response...More data for this Ligand-Target Pair
In DepthDetails
PubMed
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