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TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM428874(med.21724, Compound 1)
Affinity DataEC50:  3.10E+3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
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PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM22985(Aralen | Chlorochin | CHLOROQUINE PHOSPHATE | Chlo...)
Affinity DataEC50:  8.80E+3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
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PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM50467780(CHEBI:5801 | Hydroxychloroquine | med.21724, Compo...)
Affinity DataEC50:  740nMAssay Description:This is a review article.More data for this Ligand-Target Pair
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PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM420298(WO2005113580-Ex-02 | PF-00835231 | PF-0835231 | cm...)
Affinity DataEC50:  231nMAssay Description:VeroE6 cells were sorted for ACE2 expression by flow cytometry to generate clonal VeroE6 cells that are enriched for ACE2 surface expression. The ACE...More data for this Ligand-Target Pair
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TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM496896(science.abl4784, 2 | WO2021250648, Example 4 | US1...)
Affinity DataEC50:  1.36E+3nMAssay Description:VeroE6 cells were sorted for ACE2 expression by flow cytometry to generate clonal VeroE6 cells that are enriched for ACE2 surface expression. The ACE...More data for this Ligand-Target Pair
In DepthDetails

TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM496897(science.abl4784, 3)
Affinity DataEC50:  5.59E+3nMAssay Description:VeroE6 cells were sorted for ACE2 expression by flow cytometry to generate clonal VeroE6 cells that are enriched for ACE2 surface expression. The ACE...More data for this Ligand-Target Pair
In DepthDetails

TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM496900(science.abl4784, 4)
Affinity DataEC50:  909nMAssay Description:VeroE6 cells were sorted for ACE2 expression by flow cytometry to generate clonal VeroE6 cells that are enriched for ACE2 surface expression. The ACE...More data for this Ligand-Target Pair
In DepthDetails

TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM496901(science.abl4784, 5)
Affinity DataEC50:  85nMAssay Description:VeroE6 cells were sorted for ACE2 expression by flow cytometry to generate clonal VeroE6 cells that are enriched for ACE2 surface expression. The ACE...More data for this Ligand-Target Pair
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TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM496902(PF-07321332 | science.abl4784, 6 | WO2021250648, E...)
Affinity DataEC50:  75nMAssay Description:VeroE6 cells were sorted for ACE2 expression by flow cytometry to generate clonal VeroE6 cells that are enriched for ACE2 surface expression. The ACE...More data for this Ligand-Target Pair
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TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM31524(Naphthalene and Benzamide Derivative, 25 | 5-amino...)
Affinity DataEC50: >2.00E+4nMAssay Description:A549-hACE2 cells were seeded 1.5 × 105 cells/well in DMEM complete into 24-well plates (0.5 mL/well) and then incubated for 16 h at 37 °C and 5% CO2....More data for this Ligand-Target Pair
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PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM496842(SARS-CoV-2 PLpro Inhibitor, 72 | US20240166598, Co...)
Affinity DataEC50:  1.40E+3nMAssay Description:A549-hACE2 cells were seeded 1.5 × 105 cells/well in DMEM complete into 24-well plates (0.5 mL/well) and then incubated for 16 h at 37 °C and 5% CO2....More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM496843(SARS-CoV-2 PLpro Inhibitor, 73 | US20240166598, Co...)
Affinity DataEC50:  1.20E+3nMAssay Description:A549-hACE2 cells were seeded 1.5 × 105 cells/well in DMEM complete into 24-well plates (0.5 mL/well) and then incubated for 16 h at 37 °C and 5% CO2....More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM50595278(CHEMBL5205832)
Affinity DataKd:  1.40E+4nMAssay Description:Binding affinity to human ACE2 assessed as equilibrium dissociation constant by biolayer interferometry assayMore data for this Ligand-Target Pair
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PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM50595279(CHEMBL5187952)
Affinity DataKd:  1.60E+4nMAssay Description:Binding affinity to human ACE2 assessed as equilibrium dissociation constant by biolayer interferometry assayMore data for this Ligand-Target Pair
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PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM50157304(3',5-diallylbiphenyl-2,4'-diol | CHEMBL16901 | cid...)
Affinity DataKd:  1.70E+4nMAssay Description:Binding affinity to human ACE2 assessed as equilibrium dissociation constant by biolayer interferometry assayMore data for this Ligand-Target Pair
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PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM50423643(CEPHARANTHINE)
Affinity DataEC50:  350nMAssay Description:Inhibition of ACE2 (unknown origin)More data for this Ligand-Target Pair
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PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM50624129(CHEMBL5395954)
Affinity DataKd:  0.440nMAssay Description:Binding affinity to human ACE2 assessed as binding constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
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PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM50624130(CHEMBL5403774)
Affinity DataKd:  1.20nMAssay Description:Binding affinity to human ACE2 assessed as binding constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
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PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM50624131(CHEMBL5396932)
Affinity DataKd:  1.60nMAssay Description:Binding affinity to human ACE2 assessed as binding constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM50624132(CHEMBL5434641)
Affinity DataKd:  850nMAssay Description:Binding affinity to human ACE2 assessed as binding constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
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PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM50624133(CHEMBL5415513)
Affinity DataKd:  29nMAssay Description:Binding affinity to human ACE2 assessed as binding constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
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PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM50624134(CHEMBL5420202)
Affinity DataKd:  1.10E+4nMAssay Description:Binding affinity to human ACE2 assessed as binding constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
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PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM50624135(CHEMBL5407252)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human ACE2 assessed as binding constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM50624136(CHEMBL5429094)
Affinity DataKd:  0.720nMAssay Description:Binding affinity to human ACE2 assessed as binding constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM50624137(CHEMBL5433480)
Affinity DataKd:  1.70nMAssay Description:Binding affinity to human ACE2 assessed as binding constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM50624138(CHEMBL5434946)
Affinity DataKd:  2.70nMAssay Description:Binding affinity to human ACE2 assessed as binding constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM50624139(CHEMBL5420290)
Affinity DataKd:  2.5nMAssay Description:Binding affinity to human ACE2 assessed as binding constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM50624140(CHEMBL5410380)
Affinity DataKd:  36nMAssay Description:Binding affinity to human ACE2 assessed as binding constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM50624141(CHEMBL5402703)
Affinity DataKd:  25nMAssay Description:Binding affinity to human ACE2 assessed as binding constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM50624142(CHEMBL5429801)
Affinity DataKd:  9.10nMAssay Description:Binding affinity to human ACE2 assessed as binding constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM50624143(CHEMBL5394399)
Affinity DataKd:  0.0600nMAssay Description:Binding affinity to human ACE2 assessed as binding constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM50624144(CHEMBL5430631)
Affinity DataKd:  0.0490nMAssay Description:Binding affinity to human ACE2 assessed as binding constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM50624145(CHEMBL5406655)
Affinity DataKd:  0.0570nMAssay Description:Binding affinity to human ACE2 assessed as binding constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM50624146(CHEMBL5424883)
Affinity DataKd:  0.0540nMAssay Description:Binding affinity to human ACE2 assessed as binding constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM50624147(CHEMBL5437403)
Affinity DataKd:  11nMAssay Description:Binding affinity to human ACE2 assessed as binding constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM50624148(CHEMBL5400018)
Affinity DataKd:  8.30nMAssay Description:Binding affinity to human ACE2 assessed as binding constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM50624149(CHEMBL5424641)
Affinity DataKd:  1.90nMAssay Description:Binding affinity to human ACE2 assessed as binding constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM50624150(CHEMBL5429562)
Affinity DataKd:  3.10nMAssay Description:Binding affinity to human ACE2 assessed as binding constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM50624151(CHEMBL5397691)
Affinity DataKd:  11nMAssay Description:Binding affinity to human ACE2 assessed as binding constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM50624152(CHEMBL5415414)
Affinity DataKd:  1.30nMAssay Description:Binding affinity to human ACE2 assessed as binding constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM50624153(CHEMBL5400083)
Affinity DataKd:  52nMAssay Description:Binding affinity to human ACE2 assessed as binding constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM50624129(CHEMBL5395954)
Affinity DataKd:  1.60nMAssay Description:Binding affinity to human ACE2 assessed as dissociation constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM50624144(CHEMBL5430631)
Affinity DataKd:  3.40nMAssay Description:Binding affinity to human ACE2 assessed as dissociation constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM50630966(CHEMBL5436660)
Affinity DataEC50:  2.01E+4nMAssay Description:Activation of recombinant human ACE2 using McaAPK(Dnp)-OH as substrate preincubated for 15 mins followed by substrate addition spectra max Gemini M5 ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM50000999(CHEBI:81724 | DIMINAZENE)
Affinity DataEC50:  8.04E+3nMAssay Description:Activation of recombinant human ACE2 using McaAPK(Dnp)-OH as substrate preincubated for 15 mins followed by substrate addition spectra max Gemini M5 ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM50237588(CHEMBL1057 | CHEBI:31624)
Affinity DataEC50:  1.95E+4nMAssay Description:Activation of recombinant human ACE2 using McaAPK(Dnp)-OH as substrate preincubated for 15 mins followed by substrate addition spectra max Gemini M5 ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM21489(MLN4760 | (2S)-2-{[(1S)-1-carboxy-2-{1-[(3,5-dichl...)
Affinity DataIC50: 0.440nMpH: 6.5 T: 2°CAssay Description:Enzyme assay was conducted in 384-well microplates format. Activity was monitored by measuring increase in fluorescence (excitation @320 nm, emission...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM21489(MLN4760 | (2S)-2-{[(1S)-1-carboxy-2-{1-[(3,5-dichl...)
Affinity DataIC50: 0.440nMAssay Description:Inhibition of ACE2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM429241(med.21724, Compound 13)
Affinity DataIC50: 0.440nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetAngiotensin-converting enzyme 2(Human)
University of Bonn

LigandPNGBDBM21489(MLN4760 | (2S)-2-{[(1S)-1-carboxy-2-{1-[(3,5-dichl...)
Affinity DataIC50: 0.440nMAssay Description:Inhibition of ACE2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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