Compile Data Set for Download or QSAR
Report error Found 5 of affinity data for UniProtKB/TrEMBL: Q99IB8
TargetGenome polyprotein(HCV)
Chia Tai Tianqing Pharmaceutical Group

Curated by ChEMBL
LigandPNGBDBM50458018(CHEMBL4216436)
Affinity DataEC50:  0.00250nMAssay Description:Inhibition of NS5A in HCV genotype 2a JFH-1 infected in human Huh7.5.1 cells assessed as reduction in viral replication after 3 days by luciferase re...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Chia Tai Tianqing Pharmaceutical Group

Curated by ChEMBL
LigandPNGBDBM50458023(CHEMBL4214282)
Affinity DataEC50:  0.000800nMAssay Description:Inhibition of NS5A in HCV genotype 2a JFH-1 infected in human Huh7.5.1 cells assessed as reduction in viral replication after 3 days by luciferase re...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Chia Tai Tianqing Pharmaceutical Group

Curated by ChEMBL
LigandPNGBDBM50453112(CHEBI:85183 | ABT-267 | Ombitasvir)
Affinity DataEC50:  0.00260nMAssay Description:Inhibition of NS5A in HCV genotype 2a JFH-1 infected in human Huh7.5.1 cells assessed as reduction in viral replication after 3 days by luciferase re...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Chia Tai Tianqing Pharmaceutical Group

Curated by ChEMBL
LigandPNGBDBM50458020(CHEMBL4203791)
Affinity DataEC50:  0.00110nMAssay Description:Inhibition of NS5A in HCV genotype 2a JFH-1 infected in human Huh7.5.1 cells assessed as reduction in viral replication after 3 days by luciferase re...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Chia Tai Tianqing Pharmaceutical Group

Curated by ChEMBL
LigandPNGBDBM35553(1H-benzo[de]isoquinoline-1,3(2H)-dione, 1)
Affinity DataIC50: 770nMAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)