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TargetTransient receptor potential cation channel subfamily M member 7(Mouse)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50633628(CHEMBL5416180)
Affinity DataIC50: 16nMAssay Description:Inhibition of mouse TRPM7 expressed in HEK293 cells assessed as inhibition of channel current in presence of 700 uM intracellular Mg2+ by whole cell ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTransient receptor potential cation channel subfamily M member 7(Mouse)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM32378(adenosine-derived inhibitor (Grp78), 13 | adenosin...)
Affinity DataIC50: 110nMAssay Description:Inhibition of mouse TRPM7 transfected in HEK293T cells assessed as inhibition of channel current in absence of intracellular Mg2+ by whole cell patch...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTransient receptor potential cation channel subfamily M member 7(Mouse)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50158336(FINGOLIMOD HYDROCHLORIDE | 2-amino-2-(4-octylphene...)
Affinity DataIC50: 720nMAssay Description:Inhibition of HA-tagged mouse TRPM7 transfected in HEK293 cells assessed as inhibition of channel current by whole cell patch clamp analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTransient receptor potential cation channel subfamily M member 7(Mouse)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50242184(Scalaradial)
Affinity DataIC50: 760nMAssay Description:Inhibition of mouse FLAG-tagged TRPM7 expressed in HEK293 cells assessed as reduction in BAPTA-induced intracellular calcium flux after 15 to 60 mins...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTransient receptor potential cation channel subfamily M member 7(Mouse)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50263331((1H-Benzoimidazol-2-yl)-(R)-1,2,3,4-tetrahydronaph...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of mouse TRPM7 transfected in HEK293 cells assessed as inhibition of channel current in absence of intracellular Mg2+ by whole cell patch ...More data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetTransient receptor potential cation channel subfamily M member 7(Mouse)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50263331((1H-Benzoimidazol-2-yl)-(R)-1,2,3,4-tetrahydronaph...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of mouse TRPM7 transfected in HEK293 cells assessed as inhibition of channel current in presence of 780 uM free intracellular Mg2+ by whol...More data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetTransient receptor potential cation channel subfamily M member 7(Mouse)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50263331((1H-Benzoimidazol-2-yl)-(R)-1,2,3,4-tetrahydronaph...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of mouse TRPM7 transfected in HEK293 cells assessed as inhibition of channel current in presence of 300 uM free intracellular Mg2+ by whol...More data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetTransient receptor potential cation channel subfamily M member 7(Mouse)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50633629(CHEMBL5423236)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of FLAG-tagged mouse TRPM7 transfected in HEK293 cells assessed as inhibition of channel-mediated Mn2+ influx incubated for ~15 mins and m...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTransient receptor potential cation channel subfamily M member 7(Mouse)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50633631(CHEMBL5400468)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of FLAG-tagged mouse TRPM7 transfected in HEK293 cells assessed as inhibition of channel-mediated Mn2+ influx incubated for ~15 mins and m...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTransient receptor potential cation channel subfamily M member 7(Mouse)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50633628(CHEMBL5416180)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of FLAG-tagged mouse TRPM7 transfected in HEK293 cells assessed as inhibition of channel-mediated Mn2+ influx incubated for ~15 mins and m...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTransient receptor potential cation channel subfamily M member 7(Mouse)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50633633(CHEMBL5399993)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of FLAG-tagged mouse TRPM7 transfected in HEK293 cells assessed as inhibition of channel-mediated Mn2+ influx incubated for ~15 mins and m...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTransient receptor potential cation channel subfamily M member 7(Mouse)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50278349(2-(Diphenylboryloxy)Ethanamine | 2-Aminoethoxydiph...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of FLAG-tagged mouse TRPM7 transfected in HEK293 cells assessed as inhibition of channel-mediated Mn2+ influx incubated for ~15 mins and m...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTransient receptor potential cation channel subfamily M member 7(Mouse)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50633630(CHEMBL5420149)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of FLAG-tagged mouse TRPM7 transfected in HEK293 cells assessed as inhibition of channel-mediated Mn2+ influx incubated for ~15 mins and m...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTransient receptor potential cation channel subfamily M member 7(Mouse)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50633632(CHEMBL5426001)
Affinity DataIC50: 1.30E+5nMAssay Description:Inhibition of FLAG-tagged mouse TRPM7 transfected in HEK293 cells assessed as inhibition of channel-mediated Mn2+ influx incubated for ~15 mins and m...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTransient receptor potential cation channel subfamily M member 7(Mouse)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50633634(CHEMBL5408631)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of FLAG-tagged mouse TRPM7 transfected in HEK293 cells assessed as inhibition of channel-mediated Mn2+ influx incubated for ~15 mins and m...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTransient receptor potential cation channel subfamily M member 7(Mouse)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50633635(CHEMBL5436076)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of FLAG-tagged mouse TRPM7 transfected in HEK293 cells assessed as inhibition of channel-mediated Mn2+ influx incubated for ~15 mins and m...More data for this Ligand-Target Pair
In DepthDetails
PubMed