Compile Data Set for Download or QSAR
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TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50374762(CHEMBL261432)
Affinity DataIC50: 13nMAssay Description:Inhibition of Trypanosoma cruzi FPPSMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM12576(JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...)
Affinity DataIC50: 27nMAssay Description:Inhibition of Trypanosoma cruzi farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM12576(JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...)
Affinity DataIC50: 27nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50521859(CHEMBL4460779)
Affinity DataIC50: 34nMAssay Description:Inhibition of Trypanosoma cruzi FPPS using DMAPP as substrate incubated for 30 mins measured by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50374757(CHEMBL408745)
Affinity DataIC50: 38nMAssay Description:Inhibition of Trypanosoma cruzi FPPSMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426986(CHEMBL2326222)
Affinity DataIC50: 40nMAssay Description:Inhibition of Trypanosoma cruzi farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426986(CHEMBL2326222)
Affinity DataIC50: 40nMAssay Description:Inhibition of Trypanosoma cruzi FPPS using DMAPP as substrate incubated for 30 mins measured by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341918((2-heptylamino-1-phosphono-ethyl)-phosphonic acid ...)
Affinity DataIC50: 58nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341918((2-heptylamino-1-phosphono-ethyl)-phosphonic acid ...)
Affinity DataIC50: 58nMAssay Description:Inhibition of Trypanosoma cruzi FPPSMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341918((2-heptylamino-1-phosphono-ethyl)-phosphonic acid ...)
Affinity DataIC50: 58nMAssay Description:Inhibition of Trypanosoma cruzi FPPS using DMAPP as substrate incubated for 30 mins measured by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50521851(CHEMBL4540565)
Affinity DataIC50: 60nMAssay Description:Inhibition of Trypanosoma cruzi FPPS using DMAPP as substrate incubated for 30 mins measured by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50521853(CHEMBL4464077)
Affinity DataIC50: 71nMAssay Description:Inhibition of Trypanosoma cruzi FPPS using DMAPP as substrate incubated for 30 mins measured by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50521854(CHEMBL4470596)
Affinity DataIC50: 85nMAssay Description:Inhibition of Trypanosoma cruzi FPPS using DMAPP as substrate incubated for 30 mins measured by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426977(CHEMBL2326232)
Affinity DataIC50: 97nMAssay Description:Inhibition of Trypanosoma cruzi FPPS using DMAPP as substrate incubated for 30 mins measured by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426977(CHEMBL2326232)
Affinity DataIC50: 97nMAssay Description:Inhibition of Trypanosoma cruzi farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50521855(CHEMBL4514861)
Affinity DataIC50: 136nMAssay Description:Inhibition of Trypanosoma cruzi FPPS using DMAPP as substrate incubated for 30 mins measured by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50521857(CHEMBL4589071)
Affinity DataIC50: 173nMAssay Description:Inhibition of Trypanosoma cruzi FPPS using DMAPP as substrate incubated for 30 mins measured by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50374758(CHEMBL259786)
Affinity DataIC50: 287nMAssay Description:Inhibition of Trypanosoma cruzi FPPSMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50374765(CHEMBL261562)
Affinity DataIC50: 420nMAssay Description:Inhibition of Trypanosoma cruzi FPPSMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341911(1-[(n-Non-1-ylamino)ethyl]1,1-bisphosphonic acid |...)
Affinity DataIC50: 430nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341917(1-[(n-hex-1-ylamino)ethyl]-1,1-bisphosphonic acid ...)
Affinity DataIC50: 490nMAssay Description:Inhibition of Trypanosoma cruzi FPPSMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341917(1-[(n-hex-1-ylamino)ethyl]-1,1-bisphosphonic acid ...)
Affinity DataIC50: 490nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341917(1-[(n-hex-1-ylamino)ethyl]-1,1-bisphosphonic acid ...)
Affinity DataIC50: 490nMAssay Description:Inhibition of Trypanosoma cruzi FPPS using DMAPP as substrate incubated for 30 mins measured by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50374760(CHEMBL258540)
Affinity DataIC50: 515nMAssay Description:Inhibition of Trypanosoma cruzi FPPSMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50521852(CHEMBL4543493)
Affinity DataIC50: 611nMAssay Description:Inhibition of Trypanosoma cruzi FPPS using DMAPP as substrate incubated for 30 mins measured by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426988(CHEMBL2326225)
Affinity DataIC50: 627nMAssay Description:Inhibition of Trypanosoma cruzi farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50374759(CHEMBL258541)
Affinity DataIC50: 760nMAssay Description:Inhibition of Trypanosoma cruzi FPPSMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426990(CHEMBL2326226)
Affinity DataIC50: 789nMAssay Description:Inhibition of Trypanosoma cruzi farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341914(1-[(n-Dodec-1-ylamino)ethyl]1,1-bisphosphonic acid...)
Affinity DataIC50: 810nMAssay Description:Inhibition of Trypanosoma cruzi FPPS using DMAPP as substrate incubated for 30 mins measured by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341914(1-[(n-Dodec-1-ylamino)ethyl]1,1-bisphosphonic acid...)
Affinity DataIC50: 811nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341913(1-[(n-Undec-1-ylamino)ethyl]1,1-bisphosphonic acid...)
Affinity DataIC50: 856nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50521858(CHEMBL4455942)
Affinity DataIC50: 915nMAssay Description:Inhibition of Trypanosoma cruzi FPPS using DMAPP as substrate incubated for 30 mins measured by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426989(CHEMBL2096957)
Affinity DataIC50: 925nMAssay Description:Inhibition of Trypanosoma cruzi farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50374761(CHEMBL262598)
Affinity DataIC50: 944nMAssay Description:Inhibition of Trypanosoma cruzi FPPSMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50444839(CHEMBL3099275)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi FPPS using DMAPP as substrate incubated for 30 mins measured by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341910(1-[(Benzylamino)ethyl]1,1-bisphosphonic acid | CHE...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341915(1-[(n-Tetradec-1-ylamino)ethyl]1,1-bisphosphonic a...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50444844(CHEMBL3099276)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi FPPS using DMAPP as substrate incubated for 30 mins measured by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341912(1-[(n-Dec-1-ylamino)ethyl]1,1-bisphosphonic acid |...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341916(1-[(n-oct-1-ylamino)ethyl]-1,1-bisphosphonic acid ...)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341916(1-[(n-oct-1-ylamino)ethyl]-1,1-bisphosphonic acid ...)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of Trypanosoma cruzi FPPSMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50374763(CHEMBL405827)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of Trypanosoma cruzi FPPSMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50374764(CHEMBL407221)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Trypanosoma cruzi FPPSMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426976(CHEMBL2326231)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Trypanosoma cruzi farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50374766(CHEMBL409012)
Affinity DataIC50: 1.84E+3nMAssay Description:Inhibition of Trypanosoma cruzi FPPSMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM25298(CHEMBL55264 | (1-hydroxy-1-phosphonoheptyl)phospho...)
Affinity DataIC50: 1.94E+3nMAssay Description:Inhibition of Trypanosoma cruzi FPPSMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50374767(CHEMBL406087)
Affinity DataIC50: 2.28E+3nMAssay Description:Inhibition of Trypanosoma cruzi FPPSMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426975(CHEMBL2326230)
Affinity DataIC50: 6.39E+3nMAssay Description:Inhibition of Trypanosoma cruzi farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426991(CHEMBL2326223)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426981(CHEMBL2326236)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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