Compile Data Set for Download or QSAR
Report error Found 56 of affinity data for UniProtKB/TrEMBL: Q8VC69
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50206441(2-(2,4,5,7-tetrabromo-3-hydroxy-6-oxo-6H-xanthen-9...)
Affinity DataKi:  89nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50270022(hexanedioic acid, ion(2-) | hexanedioate | adipate...)
Affinity DataKi:  410nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50143424(2-(3-hydroxy-6-oxo-6H-xanthen-9-yl)benzoic acid | ...)
Affinity DataKi:  2.95E+3nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM35847(DINOPROSTONE | [3H]Prostaglandin E2 | prostaglandi...)
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50009859((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...)
Affinity DataKi:  4.70E+3nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50206509(CHEMBL897 | 4-Dipropylsulfamoyl-benzoic acid(probe...)
Affinity DataKi:  6.31E+3nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50269998((S)-2-((R)-5-chloro-8-hydroxy-3-methyl-1-oxoisochr...)
Affinity DataKi:  6.31E+3nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50270021(glutarate(2-) | pentanedioate | glutarate)
Affinity DataKi:  6.70E+3nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50270006(2-(4-aminobenzamido)acetate | AMINOHIPPURATE)
Affinity DataKi:  9.40E+3nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50240408(n-heptanoate | oenanthylate | n-heptoate | n-hepty...)
Affinity DataKi:  1.67E+4nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50270010(octanedioate)
Affinity DataKi:  3.41E+4nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM16433(CHEMBL14184 | Caproic acid | n-Caproic acid | Hexa...)
Affinity DataKi:  3.72E+4nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50009999(CHEMBL461 | N-benzoylglycine)
Affinity DataKi:  5.56E+4nMAssay Description:Inhibition of mouse Oat1 expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50269966(CHEMBL1762647 | 2-ethylhexanoate)
Affinity DataKi:  5.62E+4nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50009999(CHEMBL461 | N-benzoylglycine)
Affinity DataKi:  5.62E+4nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50412192(CHEMBL1162486)
Affinity DataKi:  5.62E+4nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50412193(CHEMBL1162487)
Affinity DataKi:  5.62E+4nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50269993(3-(4-Hydroxyphenyl)pyruvate | 3-(4-hydroxyphenyl)-...)
Affinity DataKi:  7.30E+4nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50269993(3-(4-Hydroxyphenyl)pyruvate | 3-(4-hydroxyphenyl)-...)
Affinity DataKi:  7.30E+4nMAssay Description:Inhibition of mouse Oat1 expressed in Xenopus oocytes assessed as inhibition 6-carboxyfluorescein uptake after 1 hr by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50269993(3-(4-Hydroxyphenyl)pyruvate | 3-(4-hydroxyphenyl)-...)
Affinity DataKi:  7.30E+4nMAssay Description:Inhibition of mouse Oat1 expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50269985(2-oxo-3-phenylpropanoate | 3-(4-hydroxyphenyl)pyru...)
Affinity DataKi:  7.90E+4nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50269985(2-oxo-3-phenylpropanoate | 3-(4-hydroxyphenyl)pyru...)
Affinity DataKi:  7.90E+4nMAssay Description:Inhibition of mouse Oat1 expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM26193(salicylic acid | 2-Hydroxybenzoate, I | CHEMBL424 ...)
Affinity DataKi:  1.45E+5nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50366524(Estrone Sulphate | ESTRONE | ESTROPIPATE | Estrone...)
Affinity DataKi:  2.03E+5nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50270011(estradiol disulfate)
Affinity DataKi:  2.20E+5nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50269986(3-(4-Hydroxyphenyl)lactate | p-Hydroxyphenyllactat...)
Affinity DataKi:  2.23E+5nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50269986(3-(4-Hydroxyphenyl)lactate | p-Hydroxyphenyllactat...)
Affinity DataKi:  2.23E+5nMAssay Description:Inhibition of mouse Oat1 expressed in Xenopus oocytes assessed as inhibition 6-carboxyfluorescein uptake after 1 hr by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50269986(3-(4-Hydroxyphenyl)lactate | p-Hydroxyphenyllactat...)
Affinity DataKi:  2.23E+5nMAssay Description:Inhibition of mouse Oat1 expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50412191(CHEMBL1162490 | Latifolicinin C Acid | p-Hydroxyph...)
Affinity DataKi:  2.24E+5nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM36181(benzoic acid | benzoate | SODIUM BENZOATE | benzoi...)
Affinity DataKi:  2.53E+5nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50377930(Benzylpenicillin Sodium | PENICILLIN G SODIUM)
Affinity DataKi:  3.28E+5nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50270008((2S,5R,6R)-6-{[(2R)-2-carboxylato-2-thiophen-3-yla...)
Affinity DataKi:  5.30E+5nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM26122(FUMARIC ACID | Fumarate | (2E)-but-2-enedioic acid...)
Affinity DataKi:  6.17E+5nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM22360(2-(acetyloxy)benzoic acid | 2-(acetyloxy)benzoate ...)
Affinity DataKi:  6.87E+5nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50344958((S)-2-acetamidosuccinate | N-Acetylaspartate | CHE...)
Affinity DataKi:  8.32E+5nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50344962((2S)-2-HYDROXYPENTANEDIOIC ACID | L-2-Hydroxygluta...)
Affinity DataKi:  8.40E+5nMAssay Description:Inhibition of mouse Oat1 expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50270017(2-acetamidosuccinate)
Affinity DataKi:  8.40E+5nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50344958((S)-2-acetamidosuccinate | N-Acetylaspartate | CHE...)
Affinity DataKi:  8.40E+5nMAssay Description:Inhibition of mouse Oat1 expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50344958((S)-2-acetamidosuccinate | N-Acetylaspartate | CHE...)
Affinity DataKi:  8.40E+5nMAssay Description:Inhibition of mouse Oat1 expressed in Xenopus oocytes assessed as inhibition 6-carboxyfluorescein uptake after 1 hr by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataKi:  8.91E+5nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50412189(CHEMBL1162482)
Affinity DataKi:  9.12E+5nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50412188(CHEMBL1162483)
Affinity DataKi:  9.12E+5nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50240453(2-methylbutanoate | (+/-)-2-methylbutanoate | 2-me...)
Affinity DataKi:  9.20E+5nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50344957((3S)-3-HYDROXYBUTANOIC ACID | (S)-3-hydroxybutanoa...)
Affinity DataKi:  3.32E+6nMAssay Description:Inhibition of mouse Oat1 expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50270275(3-hydroxybutanoate | 3-hydroxybutyrate | beta-hydr...)
Affinity DataKi:  3.22E+6nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50344957((3S)-3-HYDROXYBUTANOIC ACID | (S)-3-hydroxybutanoa...)
Affinity DataKi:  3.22E+6nMAssay Description:Inhibition of mouse Oat1 expressed in Xenopus oocytes assessed as inhibition 6-carboxyfluorescein uptake after 1 hr by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50344957((3S)-3-HYDROXYBUTANOIC ACID | (S)-3-hydroxybutanoa...)
Affinity DataKi:  3.24E+6nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50412190(CHEMBL1162484)
Affinity DataKi:  3.24E+6nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50412187(CHEMBL1162480)
Affinity DataKi:  1.41E+7nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50412186(DEAMINOHYDROXYVALINE)
Affinity DataKi:  1.41E+7nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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