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Report error Found 161 of affinity data for UniProtKB/TrEMBL: Q8K3T4
TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50339489(3-{4-[(2',6'-Dimethylbiphenyl-3-yl)methoxy]phenyl}...)
Affinity DataEC50:  18nMAssay Description:Agonist activity at rat GPR40 expressed in CHO cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50019083(CHEMBL3288344)
Affinity DataEC50:  38nMAssay Description:Agonist activity at rat GPR40 expressed in CHO cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50019084(CHEMBL3288345)
Affinity DataEC50:  210nMAssay Description:Agonist activity at rat GPR40 expressed in CHO cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50019085(CHEMBL3288346)
Affinity DataEC50:  840nMAssay Description:Agonist activity at rat GPR40 expressed in CHO cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50019086(CHEMBL3288347)
Affinity DataEC50:  540nMAssay Description:Agonist activity at rat GPR40 expressed in CHO cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50019087(CHEMBL3288348)
Affinity DataEC50:  16nMAssay Description:Agonist activity at rat GPR40 expressed in CHO cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50019088(CHEMBL3288349)
Affinity DataEC50:  310nMAssay Description:Agonist activity at rat GPR40 expressed in CHO cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50019089(CHEMBL3288350)
Affinity DataEC50:  1.40E+3nMAssay Description:Agonist activity at rat GPR40 expressed in CHO cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50019090(CHEMBL3288351)
Affinity DataEC50:  130nMAssay Description:Agonist activity at rat GPR40 expressed in CHO cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50019096(CHEMBL3288352)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at rat GPR40 expressed in CHO cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50019099(CHEMBL3288353)
Affinity DataEC50:  9.10E+3nMAssay Description:Agonist activity at rat GPR40 expressed in CHO cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM22496(CHEMBL207881 | 3-(4-{[(3-phenoxyphenyl)methyl]amin...)
Affinity DataEC50:  99nMAssay Description:Agonist activity at rat GPR40 expressed in CHO cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50019102(CHEMBL3288354)
Affinity DataEC50:  250nMAssay Description:Agonist activity at rat GPR40 expressed in CHO cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50019103(CHEMBL3288355)
Affinity DataEC50:  2.10E+3nMAssay Description:Agonist activity at rat GPR40 expressed in CHO cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50019104(CHEMBL3288356)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at rat GPR40 expressed in CHO cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50019105(CHEMBL3288357)
Affinity DataEC50:  96nMAssay Description:Agonist activity at rat GPR40 expressed in CHO cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50019106(CHEMBL3288358)
Affinity DataEC50:  320nMAssay Description:Agonist activity at rat GPR40 expressed in CHO cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50019107(CHEMBL3288359)
Affinity DataEC50:  130nMAssay Description:Agonist activity at rat GPR40 expressed in CHO cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50019108(CHEMBL3288360)
Affinity DataEC50:  190nMAssay Description:Agonist activity at rat GPR40 expressed in CHO cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50019109(CHEMBL3288361)
Affinity DataEC50:  760nMAssay Description:Agonist activity at rat GPR40 expressed in CHO cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50019110(CHEMBL3288362)
Affinity DataEC50:  79nMAssay Description:Agonist activity at rat GPR40 expressed in CHO cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50019111(CHEMBL3288363)
Affinity DataEC50:  78nMAssay Description:Agonist activity at rat GPR40 expressed in CHO cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50019112(CHEMBL3286417)
Affinity DataEC50:  290nMAssay Description:Agonist activity at rat GPR40 expressed in CHO cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataEC50: <3.16E+4nMAssay Description:Agonist activity at rat FFA1 receptor expressed in U2OS cells assessed as calcium mobilization after 24 hrs by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50085568(CHEMBL3427712)
Affinity DataEC50:  11nMAssay Description:Agonist activity at rat GPR40 expressed in CHO cells assessed as increase in intracellular calcium level after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50362690(CHEMBL1829173 | AMG-837)
Affinity DataEC50:  23nMAssay Description:Agonist activity at rat GPR40More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50395072(CHEMBL2164242)
Affinity DataEC50:  182nMAssay Description:Agonist activity at GPR40 in rat INS-1E cells assessed as receptor activation by dynamic mass redistribution assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50204018(CHEMBL3923877)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at rat GPR40 expressed in HEK293 cells assessed as increase in intracellular Ca2+ flux by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50204022(CHEMBL3954105)
Affinity DataEC50:  630nMAssay Description:Agonist activity at rat GPR40 expressed in HEK293 cells assessed as increase in intracellular Ca2+ flux by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50204019(CHEMBL3927863)
Affinity DataEC50:  10nMAssay Description:Agonist activity at rat GPR40 expressed in HEK293 cells assessed as increase in intracellular Ca2+ flux by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50434295(CHEMBL2386353)
Affinity DataEC50:  324nMAssay Description:Agonist activity at C-terminal yellow fluorescent protein-fused rat FFA1 receptor transfected in HEK293 cells after 5 mins by BRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50433707(CHEMBL2381282)
Affinity DataEC50:  77nMAssay Description:Agonist activity at GPR40 in rat INS-1 cells assessed as glucose-stimulated insulin secretionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50386790(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
Affinity DataEC50:  93nMAssay Description:Agonist activity at GPR40 in rat INS-1 cells assessed as glucose-stimulated insulin secretionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM168171(US9688642, 1)
Affinity DataEC50:  32nMT: 2°CAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM168191(US9688642, 2)
Affinity DataEC50:  8nMT: 2°CAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM168170(US9688642, 3)
Affinity DataEC50:  30nMT: 2°CAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM168173(US9688642, 4)
Affinity DataEC50:  12nMT: 2°CAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM168152(US9688642, 5)
Affinity DataEC50:  11nMT: 2°CAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM168166(US9688642, 6)
Affinity DataEC50:  16nMT: 2°CAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM168174(US9688642, 7)
Affinity DataEC50:  28nMT: 2°CAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM168177(US9688642, 8)
Affinity DataEC50:  48nMT: 2°CAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM168193(US9688642, 9)
Affinity DataEC50:  18nMT: 2°CAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM168162(US9688642, 10)
Affinity DataEC50:  31nMT: 2°CAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM168190(US9688642, 11)
Affinity DataEC50:  26nMT: 2°CAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM168159(US9688642, 12)
Affinity DataEC50:  22nMT: 2°CAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM168175(US9688642, 13)
Affinity DataEC50:  35nMT: 2°CAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM168182(US9688642, 14)
Affinity DataEC50:  24nMT: 2°CAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM168184(US9688642, 15 | US9688642, 30)
Affinity DataEC50:  18nMT: 2°CAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM168194(US9688642, 16)
Affinity DataEC50:  37nMT: 2°CAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFree fatty acid receptor 1(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM168164(US9688642, 17)
Affinity DataEC50:  28nMT: 2°CAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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