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TargetGenome polyprotein(HRV-16)
Janssen Biopharma

US Patent
LigandPNGBDBM521557(((2R,3S,4R,5R)-5-(4-Aminopyrrolo[2,1-f][1,2,4]tria...)
Affinity DataIC50: 40nMAssay Description:The enzyme activity of hepatitis C virus RNA polymerase (HCVpol) and human rhinovirus 16 RNA polymerase (HRV16pol) is measured as an incorporation of...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGenome polyprotein(HRV-16)
Janssen Biopharma

US Patent
LigandPNGBDBM50208940(5-bromopyridin-3-yl furan-2-carboxylate | 5-bromo-...)
Affinity DataIC50: 80nMAssay Description:Inhibition of HRV-16 protease 3C expressed in Escherichia coli BL21(DE3) by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(HRV-16)
Janssen Biopharma

US Patent
LigandPNGBDBM521555(((2S,3S,4R,5R)-5-(4-Aminopyrrolo[2,1-f][1,2,4]tria...)
Affinity DataIC50: 130nMAssay Description:The enzyme activity of hepatitis C virus RNA polymerase (HCVpol) and human rhinovirus 16 RNA polymerase (HRV16pol) is measured as an incorporation of...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGenome polyprotein(HRV-16)
Janssen Biopharma

US Patent
LigandPNGBDBM50268736(2-oxo-1,2-dihydroquinolin-4-yl furan-2-carboxylate...)
Affinity DataIC50: 200nMAssay Description:Inhibition of HRV-16 protease 3C expressed in Escherichia coli BL21(DE3) by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(HRV-16)
Janssen Biopharma

US Patent
LigandPNGBDBM521556(((2R,3S,4R,5R)-5-(4-Aminopyrrolo[2,1-f][1,2,4]tria...)
Affinity DataIC50: 210nMAssay Description:The enzyme activity of hepatitis C virus RNA polymerase (HCVpol) and human rhinovirus 16 RNA polymerase (HRV16pol) is measured as an incorporation of...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGenome polyprotein(HRV-16)
Janssen Biopharma

US Patent
LigandPNGBDBM50236025(CHEMBL2016761 | US11149049, No. C2 | US20240140975...)
Affinity DataIC50: 270nMAssay Description:The enzyme activity of hepatitis C virus RNA polymerase (HCVpol) and human rhinovirus 16 RNA polymerase (HRV16pol) is measured as an incorporation of...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGenome polyprotein(HRV-16)
Janssen Biopharma

US Patent
LigandPNGBDBM50261166(5-Chloropyridin-3-yl 1H-imidazole-4-carboxylate | ...)
Affinity DataIC50: 290nMAssay Description:Inhibition of HRV-16 protease 3C expressed in Escherichia coli BL21(DE3) by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(HRV-16)
Janssen Biopharma

US Patent
LigandPNGBDBM50268882(5-chloropyridin-3-yl 4-ethoxy-2-styryloxazole-5-ca...)
Affinity DataIC50: 690nMAssay Description:Inhibition of HRV-16 protease 3C expressed in Escherichia coli BL21(DE3) by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(HRV-16)
Janssen Biopharma

US Patent
LigandPNGBDBM50261454(5-Chloropyridin-3-yl 2-naphthoate | CHEMBL466351)
Affinity DataIC50: 710nMAssay Description:Inhibition of HRV-16 protease 3C expressed in Escherichia coli BL21(DE3) by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed