Affinity DataKd: 4.70E+3nMAssay Description:Binding affinity to HIV1 integrase by displacement assayMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKd: 280nMAssay Description:Binding affinity to HIV1 integrase by displacement assayMore data for this Ligand-Target Pair
Affinity DataKd: 150nMAssay Description:Binding affinity to HIV1 integrase by displacement assayMore data for this Ligand-Target Pair
Affinity DataKd: 61nMAssay Description:Binding affinity to HIV1 integrase by displacement assayMore data for this Ligand-Target Pair
Affinity DataKd: 48nMAssay Description:Binding affinity to HIV1 integrase by displacement assayMore data for this Ligand-Target Pair
Affinity DataKd: 49nMAssay Description:Binding affinity to HIV1 integrase by displacement assayMore data for this Ligand-Target Pair
Affinity DataKd: 68nMAssay Description:Binding affinity to HIV1 integrase by displacement assayMore data for this Ligand-Target Pair
Affinity DataKd: 140nMAssay Description:Binding affinity to HIV1 integrase by displacement assayMore data for this Ligand-Target Pair
Affinity DataKd: 40nMAssay Description:Binding affinity to HIV1 integrase by displacement assayMore data for this Ligand-Target Pair
Affinity DataKd: 24nMAssay Description:Apparent binding affinity to His-tagged HIV integraseMore data for this Ligand-Target Pair
Affinity DataKd: 180nMAssay Description:Apparent binding affinity to His-tagged HIV integraseMore data for this Ligand-Target Pair
Affinity DataKd: 160nMAssay Description:Apparent binding affinity to His-tagged HIV integraseMore data for this Ligand-Target Pair
Affinity DataKd: 1.10E+3nMAssay Description:Apparent binding affinity to His-tagged HIV integraseMore data for this Ligand-Target Pair
Affinity DataKd: 1.00E+3nMAssay Description:Apparent binding affinity to His-tagged HIV integraseMore data for this Ligand-Target Pair
Affinity DataKd: 40nMAssay Description:Apparent binding affinity to Trx-His-tagged HIV integraseMore data for this Ligand-Target Pair
Affinity DataKd: 31nMAssay Description:Apparent binding affinity to Trx-His-tagged HIV integraseMore data for this Ligand-Target Pair
Affinity DataKd: 27nMAssay Description:Apparent binding affinity to Trx-His-tagged HIV integraseMore data for this Ligand-Target Pair
Affinity DataKd: 17nMAssay Description:Apparent binding affinity to Trx-His-tagged HIV integraseMore data for this Ligand-Target Pair
Affinity DataKd: 59nMAssay Description:Apparent binding affinity to Trx-His-tagged HIV integraseMore data for this Ligand-Target Pair
Affinity DataKd: 52nMAssay Description:Apparent binding affinity to Trx-His-tagged HIV integraseMore data for this Ligand-Target Pair
Affinity DataKd: 24nMAssay Description:Apparent binding affinity to Trx-His-tagged HIV integraseMore data for this Ligand-Target Pair
Affinity DataKd: 35nMAssay Description:Apparent binding affinity to Trx-His-tagged HIV integraseMore data for this Ligand-Target Pair
Affinity DataKd: 26nMAssay Description:Apparent binding affinity to Trx-His-tagged HIV integraseMore data for this Ligand-Target Pair
Affinity DataKd: 28nMAssay Description:Apparent binding affinity to Trx-His-tagged HIV integraseMore data for this Ligand-Target Pair
Affinity DataKd: 40nMAssay Description:Apparent binding affinity to Trx-His-tagged HIV integraseMore data for this Ligand-Target Pair
Affinity DataKd: 50nMAssay Description:Apparent binding affinity to Trx-His-tagged HIV integraseMore data for this Ligand-Target Pair
Affinity DataEC50: >800nMAssay Description:Potency of compound was tested against HIV-1- containing integrase mutations (T66I, S153Y)More data for this Ligand-Target Pair
Affinity DataEC50: 140nMAssay Description:Potency of compound was tested against HIV-1- containing integrase mutations (NL4-3)More data for this Ligand-Target Pair
Affinity DataKd: 3.00E+3nMAssay Description:Kd value against HIV-1 integraseMore data for this Ligand-Target Pair
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of HIV-1 integrase strand transfer activityMore data for this Ligand-Target Pair
Affinity DataEC50: >6.40E+4nMAssay Description:Inhibition of HIV-1 integrase strand transfer activityMore data for this Ligand-Target Pair
Affinity DataEC50: 9.30E+3nMAssay Description:Inhibition of HIV-1 integrase strand transfer activityMore data for this Ligand-Target Pair
Affinity DataEC50: 0.210nMAssay Description:Inhibition of HIV-1 integrase strand transfer activity incubated for 10 mins by enzymatic assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Inhibition of HIV-1 integrase mutant strand transfer activity incubated for 10 mins by enzymatic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.440nMAssay Description:Inhibition of HIV-1 integrase expressed in HEK293T co-transfected with CS-II Luci vector incubated for 48 hrs by Bright-Glo luciferase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:In vitro concentration required to inhibit the overall HIV-1 integrase strand transferMore data for this Ligand-Target Pair
Affinity DataIC50: 0.680nMAssay Description:Inhibition of HIV-1 integrase Q148K mutantMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:In vitro concentration required to inhibit the overall HIV-1 integrase strand transferMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...More data for this Ligand-Target Pair
