Compile Data Set for Download or QSAR
Report error Found 38 of affinity data for UniProtKB/TrEMBL: Q7JNQ9
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232218(N-4-fluorobenzoyl-L-leucine-glycine nitrile (14))
Affinity DataIC50: 2.80E+3nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
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PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232217(N-2-fluorobenzoyl-L-leucine-glycine nitrile (13))
Affinity DataIC50: 3.00E+3nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232231(N-3,5-difluorobenzoyl-L-leucine-glycine nitrile (2...)
Affinity DataIC50: 3.00E+3nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232225(N-3-fluorobenzoyl-L-leucine-glycine nitrile (21))
Affinity DataIC50: 3.10E+3nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232228(N-2,5-difluorobenzoyl-L-leucine-glycine nitrile (2...)
Affinity DataIC50: 3.10E+3nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232230(N-3,4-difluorobenzoyl-L-leucine-glycine nitrile (2...)
Affinity DataIC50: 3.10E+3nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232240(N-4-trifluoromethylbenzoyl-L-leucine-glycine nitri...)
Affinity DataIC50: 3.20E+3nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232235(N-3,4,5-trifluorobenzoyl-L-leucine-glycine nitrile)
Affinity DataIC50: 3.40E+3nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232236(N-2,3,4,5-tetrafluorobenzoyl-L-leucine-glycine nit...)
Affinity DataIC50: 3.40E+3nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232226(N-2,3-difluorobenzoyl-L-leucine-glycine nitrile (2...)
Affinity DataIC50: 3.40E+3nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232229(N-2,6-difluorobenzoyl-L-leucine-glycine nitrile (2...)
Affinity DataIC50: 3.70E+3nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232233(N-2,3,4-trifluorobenzoyl-L-leucine-glycine nitrile...)
Affinity DataIC50: 4.10E+3nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232238(N-2-trifluoromethylbenzoyl-L-leucine-glycine nitri...)
Affinity DataIC50: 4.10E+3nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232237(N-2,3,4,5,6-pentafluorobenzoyl-L-leucine-glycine n...)
Affinity DataIC50: 4.40E+3nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232234(N-2,4,5-trifluorobenzoyl-L-leucine-glycine nitrile)
Affinity DataIC50: 4.50E+3nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232227(N-2,4-difluorobenzoyl-L-leucine-glycine nitrile (2...)
Affinity DataIC50: 5.50E+3nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232232(N-2,3,6-trifluorobenzoyl-L-leucine-glycine nitrile...)
Affinity DataIC50: 6.00E+3nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232239(N-3-trifluoromethylbenzoyl-L-leucine-glycine nitri...)
Affinity DataIC50: 9.10E+3nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232241(N-benzoyl-L-leucine-glycine (37))
Affinity DataIC50: 1.00E+4nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
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PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232242(N-cinnamoyl-L-leucine-glycine nitrile (38))
Affinity DataIC50: 1.10E+4nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232213(N-2-fluorobenzoyl-L-leucine-γ-aminobutyric ac...)
Affinity DataIC50: 1.53E+4nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232215(N-pentafluorobenzoyl-L-leucine-γ-aminobutyric...)
Affinity DataIC50: 1.93E+4nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232215(N-pentafluorobenzoyl-L-leucine-γ-aminobutyric...)
Affinity DataIC50: 2.14E+4nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232222(N-4-fluorobenzoyl-L-leucine-β-alanine nitrile...)
Affinity DataIC50: 2.16E+4nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232221(N-2-fluorobenzoyl-L-leucine-β-alanine nitrile...)
Affinity DataIC50: 2.43E+4nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232210(N-3-fluorobenzoyl-L-leucine-β-alanine benzyl ...)
Affinity DataIC50: 2.48E+4nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232209(N-2-fluorobenzoyl-L-leucine-β-alanine benzyl ...)
Affinity DataIC50: 2.94E+4nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232208(N-pentafluorobenzoyl-L-leucine-glycine benzyl este...)
Affinity DataIC50: 3.95E+4nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232214(N-3-fluorobenzoyl-L-leucine-γ-aminobutyric ac...)
Affinity DataIC50: 4.01E+4nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232207(N-4-fluorobenzoyl-L-leucine-glycine benzyl ester (...)
Affinity DataIC50: 4.34E+4nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232212(N-pentafluorobenzoyl-L-leucine-β-alanine benz...)
Affinity DataIC50: 5.77E+4nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232211(N-4-fluorobenzoyl-L-leucine-β-alanine benzyl ...)
Affinity DataIC50: 6.23E+4nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232220(N-pentafluorobenzoyl-L-alanine-glycine nitrile (16...)
Affinity DataIC50: 6.83E+4nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232219(N-2-fluorobenzoyl-L-alanine-glycine nitrile (15))
Affinity DataIC50: 8.76E+4nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232224(N-pentafluorobenzoyl-L-alanine-β-alanine nitr...)
Affinity DataIC50: 1.00E+5nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232205(N-2-fluorobenzoyl-L-leucine-glycine benzyl ester (...)
Affinity DataIC50: 1.00E+5nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232223(N-2-fluorobenzoyl-L-alanine-β-alanine nitrile...)
Affinity DataIC50: 1.00E+5nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232206(N-3-fluorobenzoyl-L-leucine-glycine benzyl ester (...)
Affinity DataIC50: 1.00E+5nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed