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TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101068(4-Chloro-10,10-dioxo-9,10-dihydro-10lambda*6*-thio...)
Affinity DataIC50: 0.0900nMAssay Description:Inhibitory activity against HSV-2 Thymidine Kinase (HSV-2 TK)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101051(4,5-Dichloro-9H-xanthene-9-carboxylic acid [(2R,3R...)
Affinity DataIC50: 0.100nMAssay Description:Inhibitory activity against HSV-2 Thymidine Kinase (HSV-2 TK)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101050(10,10-Dioxo-9,10-dihydro-10lambda*6*-thioxanthene-...)
Affinity DataIC50: 0.110nMAssay Description:Inhibitory activity against HSV-2 Thymidine Kinase (HSV-2 TK)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101045(9H-Xanthene-9-carboxylic acid [(2R,3R,4S,5R)-5-(5-...)
Affinity DataIC50: 0.110nMAssay Description:Inhibitory activity against HSV-2 Thymidine Kinase (HSV-2 TK)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101069(10,10-Bis-trifluoromethyl-9,10-dihydro-anthracene-...)
Affinity DataIC50: 0.110nMAssay Description:Inhibitory activity against HSV-2 Thymidine Kinase (HSV-2 TK)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101071(10,10-Dioxo-9,10-dihydro-10lambda*6*-thioxanthene-...)
Affinity DataIC50: 0.130nMAssay Description:Inhibitory activity against HSV-2 Thymidine Kinase (HSV-2 TK)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101053(9H-Xanthene-9-carboxylic acid [(2R,3S,5R)-5-(5-eth...)
Affinity DataIC50: 0.130nMAssay Description:Inhibitory activity against HSV-2 Thymidine Kinase (HSV-2 TK)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101048(4-Chloro-9H-xanthene-9-carboxylic acid [(2R,3R,4S,...)
Affinity DataIC50: 0.140nMAssay Description:Inhibitory activity against HSV-2 Thymidine Kinase (HSV-2 TK)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101058(4-Phenyl-9H-xanthene-9-carboxylic acid [(2R,3R,4S,...)
Affinity DataIC50: 0.140nMAssay Description:Inhibitory activity against HSV-2 Thymidine Kinase (HSV-2 TK)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101060(4-Trifluoromethyl-9H-xanthene-9-carboxylic acid [(...)
Affinity DataIC50: 0.140nMAssay Description:Inhibitory activity against HSV-2 Thymidine Kinase (HSV-2 TK)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101067((S)-2-(2,4-Dichloro-5-methoxy-phenoxy)-N-[(2R,3R,4...)
Affinity DataIC50: 0.190nMAssay Description:Inhibitory activity against HSV-2 Thymidine Kinase (HSV-2 TK)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101047(4-Methyl-9H-xanthene-9-carboxylic acid [(2R,3R,4S,...)
Affinity DataIC50: 0.190nMAssay Description:Inhibitory activity against HSV-2 Thymidine Kinase (HSV-2 TK)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101074(4-Methoxy-9H-xanthene-9-carboxylic acid [(2R,3R,4S...)
Affinity DataIC50: 0.210nMAssay Description:Inhibitory activity against HSV-2 Thymidine Kinase (HSV-2 TK)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101062(4-Chloro-9H-thioxanthene-9-carboxylic acid [(2R,3R...)
Affinity DataIC50: 0.210nMAssay Description:Inhibitory activity against HSV-2 Thymidine Kinase (HSV-2 TK)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101049(10,10-Dimethyl-9,10-dihydro-anthracene-9-carboxyli...)
Affinity DataIC50: 0.280nMAssay Description:Inhibitory activity against HSV-2 Thymidine Kinase (HSV-2 TK)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101073(4,5-Dimethyl-9H-xanthene-9-carboxylic acid [(2R,3R...)
Affinity DataIC50: 0.430nMAssay Description:Inhibitory activity against HSV-2 Thymidine Kinase (HSV-2 TK)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101043(9H-Thioxanthene-9-carboxylic acid [(2R,3R,4S,5R)-5...)
Affinity DataIC50: 0.700nMAssay Description:Inhibitory activity against HSV-2 Thymidine Kinase (HSV-2 TK)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101044(9,10-Dihydro-anthracene-9-carboxylic acid [(2R,3S,...)
Affinity DataIC50: 1.20nMAssay Description:Inhibitory activity against HSV-2 Thymidine Kinase (HSV-2 TK)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101064(9H-Thioxanthene-9-carboxylic acid [(2R,3S,5R)-5-(5...)
Affinity DataIC50: 1.40nMAssay Description:Inhibitory activity against HSV-2 Thymidine Kinase (HSV-2 TK)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101046(10-Methyl-9,10-dihydro-acridine-9-carboxylic acid ...)
Affinity DataIC50: 2.60nMAssay Description:Inhibitory activity against HSV-2 Thymidine Kinase (HSV-2 TK)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101072(2-(2,6-Dichloro-phenyl)-N-[(2R,3S,5R)-5-(5-ethyl-2...)
Affinity DataIC50: 3.30nMAssay Description:Inhibitory activity against HSV-2 Thymidine Kinase (HSV-2 TK)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101059(9H-Fluorene-9-carboxylic acid [(2R,3S,5R)-5-(5-eth...)
Affinity DataIC50: 5.20nMAssay Description:Inhibitory activity against HSV-2 Thymidine Kinase (HSV-2 TK)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101065(2-(2,6-Dimethyl-phenyl)-N-[(2R,3S,5R)-5-(5-ethyl-2...)
Affinity DataIC50: 8.40nMAssay Description:Inhibitory activity against HSV-2 Thymidine Kinase (HSV-2 TK)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101070(2-(2-Chloro-phenyl)-N-[(2R,3S,5R)-5-(5-ethyl-2,4-d...)
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against HSV-2 Thymidine Kinase (HSV-2 TK)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101057(10,11-Dihydro-5H-dibenzo[a,d]cycloheptene-5-carbox...)
Affinity DataIC50: 44nMAssay Description:Inhibitory activity against HSV-2 Thymidine Kinase (HSV-2 TK)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101061(N-[(2R,3S,5R)-5-(5-Ethyl-2,4-dioxo-3,4-dihydro-2H-...)
Affinity DataIC50: 60nMAssay Description:Inhibitory activity against HSV-2 Thymidine Kinase (HSV-2 TK)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101052(N-[(2R,3S,5R)-5-(5-Ethyl-2,4-dioxo-3,4-dihydro-2H-...)
Affinity DataIC50: 70nMAssay Description:Inhibitory activity against HSV-2 Thymidine Kinase (HSV-2 TK)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101055(N-[(2R,3S,5R)-5-(5-Ethyl-2,4-dioxo-3,4-dihydro-2H-...)
Affinity DataIC50: 90nMAssay Description:Inhibitory activity against HSV-2 Thymidine Kinase (HSV-2 TK)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101056(2-Biphenyl-2-yl-N-[(2R,3S,5R)-5-(5-ethyl-2,4-dioxo...)
Affinity DataIC50: 90nMAssay Description:Inhibitory activity against HSV-2 Thymidine Kinase (HSV-2 TK)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50210810(2-(3-Trifluoromethyl-phenylamino)-1,9-dihydro-puri...)
Affinity DataIC50: 100nMAssay Description:Inhibition of HSV-2 thymidine kinase, 2 uM [3H]thymidine and ATP as phosphate donorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50210810(2-(3-Trifluoromethyl-phenylamino)-1,9-dihydro-puri...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against HSV-2 thymidine kinase isolated from HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101054(N-[(2R,3S,5R)-5-(5-Ethyl-2,4-dioxo-3,4-dihydro-2H-...)
Affinity DataIC50: 140nMAssay Description:Inhibitory activity against HSV-2 Thymidine Kinase (HSV-2 TK)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50035976(9-Allyl-2-phenylamino-1,9-dihydro-purin-6-one | CH...)
Affinity DataIC50: 180nMAssay Description:Inhibition of HSV-2 thymidine kinase, 2 uM [3H]thymidine and ATP as phosphate donorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101066(N-[(2R,3S,5R)-5-(5-Ethyl-2,4-dioxo-3,4-dihydro-2H-...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against HSV-2 Thymidine Kinase (HSV-2 TK)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50013098(CHEMBL52562 | 2-(3-Chloro-phenylamino)-1,9-dihydro...)
Affinity DataIC50: 347nMAssay Description:Inhibitory activity against HSV-2 thymidine kinase isolated from HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50229853(CHEMBL406058)
Affinity DataIC50: 398nMAssay Description:Inhibitory activity against HSV-2 thymidine kinase isolated from HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101063(Anthracene-9-carboxylic acid [(2R,3S,5R)-5-(5-ethy...)
Affinity DataIC50: 420nMAssay Description:Inhibitory activity against HSV-2 Thymidine Kinase (HSV-2 TK)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50035973(2-[3-(1,2-Dichloro-2,2-difluoro-ethyl)-phenylamino...)
Affinity DataIC50: 470nMAssay Description:Inhibition of HSV-2 thymidine kinase, 2 uM [3H]thymidine and ATP as phosphate donorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50013086(CHEMBL53835 | 2-(4-Bromo-phenylamino)-1,9-dihydro-...)
Affinity DataIC50: 603nMAssay Description:Inhibitory activity against HSV-2 thymidine kinase isolated from HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50229850(CHEMBL406300)
Affinity DataIC50: 603nMAssay Description:Inhibitory activity against HSV-2 thymidine kinase isolated from HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50035980(2-[3-(2,2,2-Trifluoro-ethyl)-phenylamino]-1,9-dihy...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HSV-2 thymidine kinase, 2 uM [3H]thymidine and ATP as phosphate donorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50229854(CHEMBL103810)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against HSV-2 thymidine kinase isolated from HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM21872(CHEMBL347128 | 9-(2-hydroxyethyl)-2-(phenylamino)-...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of HSV-2 thymidine kinase, 2 uM [3H]thymidine and ATP as phosphate donorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50229865(CHEMBL103645)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory activity against HSV-2 thymidine kinase isolated from HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50013088(CHEMBL65438 | 2-(3,4-Dibromo-phenylamino)-1,9-dihy...)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibitory activity against HSV-2 thymidine kinase isolated from HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50229862(CHEMBL101020)
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibitory activity against HSV-2 thymidine kinase isolated from HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50229856(CHEMBL102001)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibitory activity against HSV-2 thymidine kinase isolated from HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50013094(CHEMBL287727 | 2-Phenylamino-1,9-dihydro-purin-6-o...)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibitory activity against HSV-2 thymidine kinase isolated from HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50013094(CHEMBL287727 | 2-Phenylamino-1,9-dihydro-purin-6-o...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of HSV-2 thymidine kinase, 2 uM [3H]thymidine and ATP as phosphate donorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50035985(9-[2-Hydroxy-3-(2-hydroxy-ethylsulfanyl)-propyl]-2...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of HSV-2 thymidine kinase, 2 uM [3H]thymidine and ATP as phosphate donorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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