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Report error Found 16 for UniProtKB: Q63644
TargetRho-associated protein kinase 1/2(Rat)
Redx Pharma

US Patent
LigandPNGBDBM148407(US9682963, 1)
Affinity DataEC50:  550nMAssay Description:Rat smooth muscle cell line A7r5 is used. The endogenous expression of ROCK results in a constitutive phosphorylation of the regulatory myosin light ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRho-associated protein kinase 1/2(Rat)
Redx Pharma

US Patent
LigandPNGBDBM148408(US9682963, 2)
Affinity DataEC50: <100nMAssay Description:Rat smooth muscle cell line A7r5 is used. The endogenous expression of ROCK results in a constitutive phosphorylation of the regulatory myosin light ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRho-associated protein kinase 1/2(Rat)
Redx Pharma

US Patent
LigandPNGBDBM148409(US9682963, 3)
Affinity DataEC50:  550nMAssay Description:Rat smooth muscle cell line A7r5 is used. The endogenous expression of ROCK results in a constitutive phosphorylation of the regulatory myosin light ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRho-associated protein kinase 1/2(Rat)
Redx Pharma

US Patent
LigandPNGBDBM148410(US9682963, 4)
Affinity DataEC50: <100nMAssay Description:Rat smooth muscle cell line A7r5 is used. The endogenous expression of ROCK results in a constitutive phosphorylation of the regulatory myosin light ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRho-associated protein kinase 1/2(Rat)
Redx Pharma

US Patent
LigandPNGBDBM148412(US9682963, 5)
Affinity DataEC50: <100nMAssay Description:Rat smooth muscle cell line A7r5 is used. The endogenous expression of ROCK results in a constitutive phosphorylation of the regulatory myosin light ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRho-associated protein kinase 1/2(Rat)
Redx Pharma

US Patent
LigandPNGBDBM148413(US9682963, 6)
Affinity DataEC50: <100nMAssay Description:Rat smooth muscle cell line A7r5 is used. The endogenous expression of ROCK results in a constitutive phosphorylation of the regulatory myosin light ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRho-associated protein kinase 1/2(Rat)
Redx Pharma

US Patent
LigandPNGBDBM148414(US9682963, 7)
Affinity DataEC50: <100nMAssay Description:Rat smooth muscle cell line A7r5 is used. The endogenous expression of ROCK results in a constitutive phosphorylation of the regulatory myosin light ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRho-associated protein kinase 1/2(Rat)
Redx Pharma

US Patent
LigandPNGBDBM148415(US9682963, 8)
Affinity DataEC50:  550nMAssay Description:Rat smooth muscle cell line A7r5 is used. The endogenous expression of ROCK results in a constitutive phosphorylation of the regulatory myosin light ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRho-associated protein kinase 1/2(Rat)
Redx Pharma

US Patent
LigandPNGBDBM148416(US9682963, 9)
Affinity DataEC50: <100nMAssay Description:Rat smooth muscle cell line A7r5 is used. The endogenous expression of ROCK results in a constitutive phosphorylation of the regulatory myosin light ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRho-associated protein kinase 1/2(Rat)
Redx Pharma

US Patent
LigandPNGBDBM148421(US9682963, 11)
Affinity DataEC50: <100nMAssay Description:Rat smooth muscle cell line A7r5 is used. The endogenous expression of ROCK results in a constitutive phosphorylation of the regulatory myosin light ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRho-associated protein kinase 1/2(Rat)
Redx Pharma

US Patent
LigandPNGBDBM148423(US9682963, 12)
Affinity DataEC50: <100nMAssay Description:Rat smooth muscle cell line A7r5 is used. The endogenous expression of ROCK results in a constitutive phosphorylation of the regulatory myosin light ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRho-associated protein kinase 1/2(Rat)
Redx Pharma

US Patent
LigandPNGBDBM148425(US9682963, 13)
Affinity DataEC50: <100nMAssay Description:Rat smooth muscle cell line A7r5 is used. The endogenous expression of ROCK results in a constitutive phosphorylation of the regulatory myosin light ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRho-associated protein kinase 1(Rat)
Glaxosmithkline

LigandPNGBDBM24995(2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-N-(piperi...)
Affinity DataIC50: 6nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRho-associated protein kinase 1(Rat)
Glaxosmithkline

LigandPNGBDBM24996(4-{1-ethyl-7-[(piperidin-4-ylamino)methyl]-1H-imid...)
Affinity DataIC50: 38nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRho-associated protein kinase 1(Rat)
Glaxosmithkline

LigandPNGBDBM14027(AT877 | CHEMBL38380 | 5-(1,4-diazepan-1-ylsulfonyl...)
Affinity DataIC50: 2.10E+3nMT: 2°CAssay Description:The inhibitor potency of BA-1049 (racemic mixture) and Fasudil (Calbiochem) were compared by fluorescent polarization assays performed using a Biomek...More data for this Ligand-Target Pair
In DepthDetails
US Patent
PDB3D3D Structure (crystal)
TargetRho-associated protein kinase 1(Rat)
Glaxosmithkline

LigandPNGBDBM163433(US9687483, 1 | BA-1049 | US11198680, Compound BA 1...)
Affinity DataIC50: 2.10E+4nMT: 2°CAssay Description:The inhibitor potency of BA-1049 (racemic mixture) and Fasudil (Calbiochem) were compared by fluorescent polarization assays performed using a Biomek...More data for this Ligand-Target Pair
In DepthDetails
US Patent