Compile Data Set for Download or QSAR
Report error Found 601 of affinity data for UniProtKB/TrEMBL: Q4U254
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50005701(CHEMBL337283 | N*1*-[1-Benzyl-3-(2-tert-butylcarba...)
Affinity DataEC50:  145nMAssay Description:Antiviral activity against HTLV-1 RF infected MT-2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article

TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075600((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  6nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% of control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075603((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  50nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% of control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075606((E)-(S)-4-((2R,5S)-2-Benzyl-5-cyclopentylsulfanylc...)
Affinity DataEC50:  500nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated,virus infected cells to 50%...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075600((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  160nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated, virus infected cells to 50...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075603((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  180nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated, virus infected cells to 50...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075599((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  1.40E+3nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated,virus infected cells to 50%...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075604((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  160nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated,virus infected cells to 50%...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075604((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  170nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated, virus infected cells to 50...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075606((E)-(S)-4-((2R,5S)-2-Benzyl-5-cyclopentylsulfanylc...)
Affinity DataEC50:  360nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated, virus infected cells to 50...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075602((E)-(S)-4-((2R,5S)-2-Benzyl-5-cyclopentylsulfanylc...)
Affinity DataEC50:  100nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated, virus infected cells to 50...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075604((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  20nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% of control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075607((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  100nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated, virus infected cells to 50...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075599((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  160nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% of control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075606((E)-(S)-4-((2R,5S)-2-Benzyl-5-cyclopentylsulfanylc...)
Affinity DataEC50:  50nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% of control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075600((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  60nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated,virus infected cells to 50%...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50065606((E)-(S)-4-[(S)-2-((S)-2-Benzyloxycarbonylamino-4-m...)
Affinity DataEC50:  540nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% of control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075602((E)-(S)-4-((2R,5S)-2-Benzyl-5-cyclopentylsulfanylc...)
Affinity DataEC50:  20nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% of control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075603((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  160nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated,virus infected cells to 50%...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075605((E)-(S)-4-((2R,5S)-2-Benzyl-5-cyclopentylsulfanylc...)
Affinity DataEC50:  190nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% of control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075607((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  280nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% of control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075599((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  1.00E+3nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated, virus infected cells to 50...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075606((E)-(S)-4-((2R,5S)-2-Benzyl-5-cyclopentylsulfanylc...)
Affinity DataEC50:  430nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated, virus infected cells to 50...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075604((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  130nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated, virus infected cells to 50...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075607((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  600nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated, virus infected cells to 50...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075599((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  560nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated, virus infected cells to 50...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075603((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  180nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated, virus infected cells to 50...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075600((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  130nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated, virus infected cells to 50...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075601((E)-(S)-4-((2R,5S)-2-Benzyl-5-benzyloxycarbonylami...)
Affinity DataEC50:  360nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% of control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075607((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  1.60E+3nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated,virus infected cells to 50%...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075602((E)-(S)-4-((2R,5S)-2-Benzyl-5-cyclopentylsulfanylc...)
Affinity DataEC50:  35nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated,virus infected cells to 50%...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075608((E)-(S)-4-((2R,5S)-2-Benzyl-5-benzylsulfanylcarbon...)
Affinity DataEC50:  190nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% of control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075609((E)-(S)-4-((2R,5S)-2-Benzyl-5-benzylsulfanylcarbon...)
Affinity DataEC50:  680nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% of control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075613((E)-(R)-4-[(S)-2-((S)-2-Benzyloxycarbonylamino-4-m...)
Affinity DataEC50:  600nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50065606((E)-(S)-4-[(S)-2-((S)-2-Benzyloxycarbonylamino-4-m...)
Affinity DataEC50:  1.60E+3nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated, virus infected cells to 50...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075610((E)-(S)-4-[(S)-2-{(S)-3,3-Dimethyl-2-[(5-methyl-is...)
Affinity DataEC50:  10nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50065606((E)-(S)-4-[(S)-2-((S)-2-Benzyloxycarbonylamino-4-m...)
Affinity DataEC50:  540nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM11243(ethyl (2E,4S)-4-[((2R,5S)-2-(4-fluorobenzyl)-6-met...)
Affinity DataEC50:  5nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50065732((E)-(S)-4-[(S)-2-((S)-2-Benzyloxycarbonylamino-4-m...)
Affinity DataEC50:  4.00E+3nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075614((E)-(S)-4-{(2R,5S)-2-(4-Fluoro-benzyl)-6-methyl-5-...)
Affinity DataEC50:  1nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075612((E)-(S)-4-[(S)-2-((S)-2-Benzyloxycarbonylamino-4-m...)
Affinity DataEC50:  1.60E+3nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075615((E)-(S)-4-[(S)-2-((S)-2-Benzyloxycarbonylamino-4-m...)
Affinity DataEC50:  30nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50065693((E)-(S)-4-[(S)-2-((S)-2-Benzyloxycarbonylamino-4-m...)
Affinity DataEC50:  5.60E+3nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM11230(ethyl (2E,4S)-4-[(2S)-2-[(2S)-2-{[(benzyloxy)carbo...)
Affinity DataEC50:  30nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50075611((E)-(S)-4-((S)-3-(4-Fluoro-phenyl)-2-{(S)-3-methyl...)
Affinity DataEC50:  20nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM11229(AG7088 analogue 2a | CHEMBL20636 | N-[(5-methyliso...)
Affinity DataEC50:  10nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50111464((1S,5S)-4-((S)-3-(3,4-Difluoro-phenyl)-2-{3-[(5-me...)
Affinity DataEC50:  6nMAssay Description:antirhinoviral activity against HRV Protease 3CP (serotype 1A)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50111455((1S,5S)-4-((S)-3-(3,4-Difluoro-phenyl)-2-{3-[(5-me...)
Affinity DataEC50:  44nMAssay Description:antirhinoviral activity against HRV Protease 3CP (serotype 13)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50111460(trans-(2'S,4S)-4-[2'-(3''-Acetylamino-2''-oxo-2''H...)
Affinity DataEC50:  888nMAssay Description:Inhibition of HRV Protease 3CP (serotype 14).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50111455((1S,5S)-4-((S)-3-(3,4-Difluoro-phenyl)-2-{3-[(5-me...)
Affinity DataEC50:  85nMAssay Description:antirhinoviral activity against HRV Protease 3CP (serotype 10)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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