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TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589974(CHEMBL5186191)
Affinity DataIC50: 10nMAssay Description:Inhibition of Clostridium histolyticum CoLHMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50542711(CHEMBL4640494)
Affinity DataIC50: 17nMAssay Description:Inhibition of Clostridium histolyticum CoLHMore data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50542711(CHEMBL4640494)
Affinity DataIC50: 17nMAssay Description:Inhibition of Clostridium histolyticum ColH peptidase domain expressed in Escherichia coli BL21(DE3) cells using Mca-Ala-Gly-Pro-Pro-Gly-Pro-Dpa-Gly-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589973(CHEMBL5184569)
Affinity DataIC50: 21nMAssay Description:Inhibition of Clostridium histolyticum CoLH using M MOCAcPro-Leu-Gly-Leu-A2pr-(DNP)Ala-Arg-NH2 as substrate incubated for 10 mins by fluorescence spe...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50361374(SCOPARONE)
Affinity DataIC50: 24nMAssay Description:Inhibition of Clostridium histolyticum CoLH using M MOCAcPro-Leu-Gly-Leu-A2pr-(DNP)Ala-Arg-NH2 as substrate incubated for 10 mins by fluorescence spe...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50542698(CHEMBL4636059)
Affinity DataIC50: 60nMAssay Description:Inhibition of Clostridium histolyticum ColH peptidase domain expressed in Escherichia coli BL21(DE3) cells using Mca-Ala-Gly-Pro-Pro-Gly-Pro-Dpa-Gly-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50542693(CHEMBL4637937)
Affinity DataIC50: 320nMAssay Description:Inhibition of Clostridium histolyticum ColH peptidase domain expressed in Escherichia coli BL21(DE3) cells using Mca-Ala-Gly-Pro-Pro-Gly-Pro-Dpa-Gly-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM13080(N-hydroxy-2-[(4-methoxybenzene)(2-methylpropyl)sul...)
Affinity DataIC50: 612nMAssay Description:Gelatinase E (Gel E) was purified from bacterial culture supernatant from E. faecalis. E. faecalis was cultured aerobically in Todd Hewitt Broth over...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589975(CHEMBL5179045)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Clostridium histolyticum CoLHMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM633996(US20230357139, Compound N)
Affinity DataIC50: 1.00E+5nMAssay Description:Gelatinase E (Gel E) was purified from bacterial culture supernatant from E. faecalis. E. faecalis was cultured aerobically in Todd Hewitt Broth over...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM633997(US20230357139, Compound O)
Affinity DataIC50: 1.00E+5nMAssay Description:Gelatinase E (Gel E) was purified from bacterial culture supernatant from E. faecalis. E. faecalis was cultured aerobically in Todd Hewitt Broth over...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM633998(US20230357139, Compound P)
Affinity DataIC50: 1.00E+5nMAssay Description:Gelatinase E (Gel E) was purified from bacterial culture supernatant from E. faecalis. E. faecalis was cultured aerobically in Todd Hewitt Broth over...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM633995(US20230357139, Compound M)
Affinity DataIC50: 1.00E+5nMAssay Description:Gelatinase E (Gel E) was purified from bacterial culture supernatant from E. faecalis. E. faecalis was cultured aerobically in Todd Hewitt Broth over...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM633994(US20230357139, Compound L)
Affinity DataIC50: 1.00E+5nMAssay Description:Gelatinase E (Gel E) was purified from bacterial culture supernatant from E. faecalis. E. faecalis was cultured aerobically in Todd Hewitt Broth over...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM633992(US20230357139, Compound J | US20230357139, Compoun...)
Affinity DataIC50: 1.00E+5nMAssay Description:Gelatinase E (Gel E) was purified from bacterial culture supernatant from E. faecalis. E. faecalis was cultured aerobically in Todd Hewitt Broth over...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM633992(US20230357139, Compound J | US20230357139, Compoun...)
Affinity DataIC50: 1.00E+5nMAssay Description:Gelatinase E (Gel E) was purified from bacterial culture supernatant from E. faecalis. E. faecalis was cultured aerobically in Todd Hewitt Broth over...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM633991(US20230357139, Compound I)
Affinity DataIC50: 1.00E+5nMAssay Description:Gelatinase E (Gel E) was purified from bacterial culture supernatant from E. faecalis. E. faecalis was cultured aerobically in Todd Hewitt Broth over...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50016575(2-(4-methoxyphenylsulfonamido)acetic acid | CHEMBL...)
Affinity DataIC50: 1.00E+5nMAssay Description:Gelatinase E (Gel E) was purified from bacterial culture supernatant from E. faecalis. E. faecalis was cultured aerobically in Todd Hewitt Broth over...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM633989(US20230357139, Compound G)
Affinity DataIC50: 1.00E+5nMAssay Description:Gelatinase E (Gel E) was purified from bacterial culture supernatant from E. faecalis. E. faecalis was cultured aerobically in Todd Hewitt Broth over...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM633988(US20230357139, Compound F)
Affinity DataIC50: 1.00E+5nMAssay Description:Gelatinase E (Gel E) was purified from bacterial culture supernatant from E. faecalis. E. faecalis was cultured aerobically in Todd Hewitt Broth over...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM13092(N-hydroxy-2-[(2-methylpropyl)[4-(propan-2-yloxy)be...)
Affinity DataIC50: 1.00E+5nMAssay Description:Gelatinase E (Gel E) was purified from bacterial culture supernatant from E. faecalis. E. faecalis was cultured aerobically in Todd Hewitt Broth over...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM633986(US20230357139, Compound D)
Affinity DataIC50: 1.00E+5nMAssay Description:Gelatinase E (Gel E) was purified from bacterial culture supernatant from E. faecalis. E. faecalis was cultured aerobically in Todd Hewitt Broth over...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM633985(US20230357139, Compound C)
Affinity DataIC50: 1.00E+5nMAssay Description:Gelatinase E (Gel E) was purified from bacterial culture supernatant from E. faecalis. E. faecalis was cultured aerobically in Todd Hewitt Broth over...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM11859(2-({[(4-fluorobenzene)sulfonyl]carbamoyl}amino)-3-...)
Affinity DataKi:  200nMAssay Description:Inhibition of Clostridium histolyticum CoLH assessed as inhibition constant using M MOCAcPro-Leu-Gly-Leu-A2pr-(DNP)Ala-Arg-NH2 as substrate incubated...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589972(CHEMBL5191074)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of Clostridium histolyticum peptidase unit of ColH assessed as inhibition constant incubated for 144 seconds by FRET based assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589971(CHEMBL5187038)
Affinity DataKi:  1.16E+4nMAssay Description:Inhibition of Clostridium histolyticum peptidase unit of ColH assessed as inhibition constant incubated for 144 seconds by FRET based assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed