Compile Data Set for Download or QSAR
Report error Found 246 of affinity data for UniProtKB/TrEMBL: Q3Y6Q3
TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50129062(CHEBI:43968 | ICI-194660 | Meropenem | Merrem | Me...)
Affinity DataKd:  1.20E+4nMAssay Description:Reversible binding affinity to Pseudomonas aeruginosa 301-5473 metallo-beta-lactamase VIM-2 expressed in Escherichia coli BL21(DE3) measured for 15 s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM21642((2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolid...)
Affinity DataKon:  0.0250M-1s-1Assay Description:Reversible binding affinity to Pseudomonas aeruginosa 301-5473 metallo-beta-lactamase VIM-2 expressed in Escherichia coli BL21(DE3) measured for 15 s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50129035(CHEMBL1778133)
Affinity DataKd:  1.45E+5nMAssay Description:Binding affinity to Pseudomonas aeruginosa 301-5473 metallo-beta-lactamase VIM-2 expressed in Escherichia coli BL21(DE3) measured for 15 secs by SPR ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50129032(CHEMBL82115)
Affinity DataKd:  9.00E+3nMAssay Description:Binding affinity to Pseudomonas aeruginosa 301-5473 metallo-beta-lactamase VIM-2 expressed in Escherichia coli BL21(DE3) measured for 15 secs by SPR ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM73278(4-oxo-4-(4-propylphenyl)butanoic acid | MLS0000983...)
Affinity DataKd:  1.73E+5nMAssay Description:Binding affinity to Pseudomonas aeruginosa 301-5473 metallo-beta-lactamase VIM-2 expressed in Escherichia coli BL21(DE3) measured for 15 secs by SPR ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM114408(MLS000850622 | 2-[(7-chloro-4-quinolinyl)thio]acet...)
Affinity DataKd:  2.64E+5nMAssay Description:Binding affinity to Pseudomonas aeruginosa 301-5473 metallo-beta-lactamase VIM-2 expressed in Escherichia coli BL21(DE3) measured for 15 secs by SPR ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50442179(CHEMBL2441619)
Affinity DataKd:  3.33E+5nMAssay Description:Binding affinity to Pseudomonas aeruginosa 301-5473 metallo-beta-lactamase VIM-2 expressed in Escherichia coli BL21(DE3) measured for 15 secs by SPR ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50129082(CHEMBL1324612)
Affinity DataKd:  4.46E+5nMAssay Description:Binding affinity to Pseudomonas aeruginosa 301-5473 metallo-beta-lactamase VIM-2 expressed in Escherichia coli BL21(DE3) measured for 15 secs by SPR ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50129081(CHEBI:33070 | Indole-3-Butyric Acid)
Affinity DataKd:  2.74E+5nMAssay Description:Binding affinity to Pseudomonas aeruginosa 301-5473 metallo-beta-lactamase VIM-2 expressed in Escherichia coli BL21(DE3) measured for 15 secs by SPR ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50129065(CHEMBL3278535)
Affinity DataKd:  9.99E+5nMAssay Description:Binding affinity to Pseudomonas aeruginosa 301-5473 metallo-beta-lactamase VIM-2 expressed in Escherichia coli BL21(DE3) measured for 15 secs by SPR ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50129066(CHEMBL3627736)
Affinity DataKd:  2.29E+5nMAssay Description:Binding affinity to Pseudomonas aeruginosa 301-5473 metallo-beta-lactamase VIM-2 expressed in Escherichia coli BL21(DE3) measured for 15 secs by SPR ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM530895(US11207312, Example 27 | (R)-4-(4-(2-(1H-pyrazol- ...)
Affinity DataIC50: 0.180nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM531042(US11207312, Example 174 | (R)-4-(4-(1H-imidazol-1-...)
Affinity DataIC50: 0.220nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM530914(US11207312, Example 46 | (R)-N1-(1- aminopropan-2-...)
Affinity DataIC50: 0.320nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM530969(US11207312, Example 101 | 4-[4- (hydroxymethyl)pip...)
Affinity DataIC50: 0.390nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM531035(US11207312, Example 167 | (R)-4-(4-(N-(2-aminoethy...)
Affinity DataIC50: 0.400nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM531037(US11207312, Example 169 | (R)-4-(4-(1H-imidazol-4-...)
Affinity DataIC50: 0.400nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM530975(US11207312, Example 107 | 4-[3- (hydroxymethyl)pip...)
Affinity DataIC50: 0.420nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM530974(US11207312, Example 106 | 4-[4-(pyridin-2- ylmethy...)
Affinity DataIC50: 0.460nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM530978(US11207312, Example 110 | 4-[4-(pyridin-2- yloxy)p...)
Affinity DataIC50: 0.470nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM531036(US11207312, Example 168 | (S)-4-(4-(1H-imidazol-4-...)
Affinity DataIC50: 0.480nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM530888(US11207312, Example 20 | N1-((R)-3-amino-2-hydroxy...)
Affinity DataIC50: 0.490nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM530955(US11207312, Example 87 | 4-[4-(2- fluoroethyl)pipe...)
Affinity DataIC50: 0.490nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM531055(US11207312, Example 187 | (S)-N1-(1-amino-3- hydro...)
Affinity DataIC50: 0.490nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM531034(US11207312, Example 166 | (R)-4-(4-(1H-imidazol-4-...)
Affinity DataIC50: 0.530nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM530966(US11207312, Example 102 | 4-[4-(2- hydroxyethyl)pi...)
Affinity DataIC50: 0.590nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM530971(US11207312, Example 103 | 4-[2- (hydroxymethyl)mor...)
Affinity DataIC50: 0.590nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM530911(US11207312, Example 43 | N1-(2- aminoethyl)-4-(4- ...)
Affinity DataIC50: 0.610nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM530912(US11207312, Example 44 | (S)-N1-(2,3- diaminopropy...)
Affinity DataIC50: 0.630nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM531069(US11207312, Example 201 | (R)-4-(4-(1H-imidazol-2-...)
Affinity DataIC50: 0.640nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM530972(US11207312, Example 104 | 4-(3-hydroxyazepan-1-yl)...)
Affinity DataIC50: 0.650nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM530931(US11207312, Example 63 | 4-(4-hydroxypiperidin-1- ...)
Affinity DataIC50: 0.660nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM530948(US11207312, Example 80 | N1-[(3R)-pyrrolidin-3-yl]...)
Affinity DataIC50: 0.660nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM530957(US11207312, Example 89 | 4-[4- (fluoromethyl)piper...)
Affinity DataIC50: 0.660nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM531045(US11207312, Example 177 | N1-((R)-3-amino-2- hydro...)
Affinity DataIC50: 0.660nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM531032(US11207312, Example 164 | Methyl 1-(4-(N-((R)- pyr...)
Affinity DataIC50: 0.690nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM530910(US11207312, Example 42 | (R)-N1-(3-amino- 2-hydrox...)
Affinity DataIC50: 0.710nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM531053(US11207312, Example 185 | (R)-4-(4-(2-aminoethyl)p...)
Affinity DataIC50: 0.710nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM531022(US11207312, Example 154 | (R)-4-(2-oxopiperidin-1-...)
Affinity DataIC50: 0.730nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM530893(US11207312, Example 25 | (R)-2-(1-(4-(N-(3-amino- ...)
Affinity DataIC50: 0.740nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM530913(US11207312, Example 45 | N1-(1,3- diaminopropan-2-...)
Affinity DataIC50: 0.740nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM530960(US11207312, Example 92 | 1-{4-[(3R)-pyrrolidin-3- ...)
Affinity DataIC50: 0.740nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM531020(US11207312, Example 152 | (R)-4-(3-(hydroxyimino)-...)
Affinity DataIC50: 0.740nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM531061(US11207312, Example 193 | (R)-N1-(3-amino-2-hydrox...)
Affinity DataIC50: 0.75nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM530890(US11207312, Example 22 | (R)-N1-(3-amino-2- hydrox...)
Affinity DataIC50: 0.790nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM530988(US11207312, Example 120 | (R)-N1-(3-amino-2- hydro...)
Affinity DataIC50: 0.790nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM530924(US11207312, Example 56 | 6-(azetidin-3-ylsulfonyl)...)
Affinity DataIC50: 0.820nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM530999(US11207312, Example 190 | (R)-N1-(3-amino-2- hydro...)
Affinity DataIC50: 0.850nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM530956(US11207312, Example 88 | 4-[4-(2- hydroxyethoxy)pi...)
Affinity DataIC50: 0.970nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM530933(US11207312, Example 65 | 4-(4-methyl-3-oxopiperazi...)
Affinity DataIC50: 1nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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