Affinity DataEC50: 1nMAssay Description:Inhibition of ACC1 in human HepG2 cells assessed as lipid content using 13C-labelled acetate as substrate incubated for 1 hr followed by substrate ad...More data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Inhibition of ACC1 in human HepG2 cells assessed as lipid content using 13C-labelled acetate as substrate incubated for 1 hr followed by substrate ad...More data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Inhibition of ACC1 in human HepG2 cells assessed as lipid content using 13C-labelled acetate as substrate incubated for 1 hr followed by substrate ad...More data for this Ligand-Target Pair
Affinity DataEC50: 0.300nMAssay Description:Inhibition of ACC1 in human HepG2 cells assessed as lipid content using 13C-labelled acetate as substrate incubated for 1 hr followed by substrate ad...More data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Inhibition of ACC1 in human HepG2 cells assessed as lipid content using 13C-labelled acetate as substrate incubated for 1 hr followed by substrate ad...More data for this Ligand-Target Pair
Affinity DataEC50: 0.900nMAssay Description:Inhibition of ACC1 in human HepG2 cells assessed as lipid content using 13C-labelled acetate as substrate incubated for 1 hr followed by substrate ad...More data for this Ligand-Target Pair
Affinity DataIC50: 0.470nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:4.5 μL of 2.2×ACC1 enzyme (2 nM) working solution was added to a 384-well plate; and then 0.5 μL of different concentrations of compound we...More data for this Ligand-Target Pair
Affinity DataIC50: 0.580nMAssay Description:Inhibition of recombinant human ACC1 expressed in SF-9 cells preincubated for 60 mins followed by addition of substrate solution containing acetyl-Co...More data for this Ligand-Target Pair
Affinity DataIC50: 0.630nMAssay Description:4.5 μL of 2.2×ACC1 enzyme (2 nM) working solution was added to a 384-well plate; and then 0.5 μL of different concentrations of compound we...More data for this Ligand-Target Pair
Affinity DataIC50: 0.670nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
Affinity DataIC50: 0.680nMAssay Description:4.5 μL of 2.2×ACC1 enzyme (2 nM) working solution was added to a 384-well plate; and then 0.5 μL of different concentrations of compound we...More data for this Ligand-Target Pair
Affinity DataIC50: 0.690nMAssay Description:4.5 μL of 2.2×ACC1 enzyme (2 nM) working solution was added to a 384-well plate; and then 0.5 μL of different concentrations of compound we...More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:4.5 μL of 2.2×ACC1 enzyme (2 nM) working solution was added to a 384-well plate; and then 0.5 μL of different concentrations of compound we...More data for this Ligand-Target Pair
Affinity DataIC50: 0.760nMAssay Description:Inhibition of ACC1 in human HCT116 cells assessed as reduction of [14C]acetate uptake preincubated for 60 mins followed by addition of [14C]acetate a...More data for this Ligand-Target Pair
Affinity DataIC50: 0.810nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
Affinity DataIC50: 0.870nMAssay Description:4.5 μL of 2.2×ACC1 enzyme (2 nM) working solution was added to a 384-well plate; and then 0.5 μL of different concentrations of compound we...More data for this Ligand-Target Pair
Affinity DataIC50: 0.880nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
Affinity DataIC50: 0.890nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of full length human recombinant ACC1 expressed in baculovirus infected Sf9 cells incubated for 18 hrs in presence of ATP by envision fluo...More data for this Ligand-Target Pair
Affinity DataIC50: 0.910nMAssay Description:4.5 μL of 2.2×ACC1 enzyme (2 nM) working solution was added to a 384-well plate; and then 0.5 μL of different concentrations of compound we...More data for this Ligand-Target Pair
Affinity DataIC50: 0.930nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
Affinity DataIC50: 0.960nMAssay Description:Inhibition of recombinant human ACC1 expressed in SF-9 cells preincubated for 60 mins followed by addition of substrate solution containing acetyl-Co...More data for this Ligand-Target Pair
Affinity DataIC50: 0.960nMAssay Description:Inhibition of recombinant human ACC1 expressed in SF-9 cells preincubated for 60 mins followed by addition of substrate solution containing acetyl-Co...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:An exemplary procedure for the in vitro ACC inhibition assay, which can be used to determine the inhibitory action of compounds of the invention towa...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:An exemplary procedure for the in vitro ACC inhibition assay, which can be used to determine the inhibitory action of compounds of the invention towa...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:An exemplary procedure for the in vitro ACC inhibition assay, which can be used to determine the inhibitory action of compounds of the invention towa...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:An exemplary procedure for the in vitro ACC inhibition assay, which can be used to determine the inhibitory action of compounds of the invention towa...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:An exemplary procedure for the in vitro ACC inhibition assay, which can be used to determine the inhibitory action of compounds of the invention towa...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:An exemplary procedure for the in vitro ACC inhibition assay, which can be used to determine the inhibitory action of compounds of the invention towa...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:4.5 μL of 2.2×ACC1 enzyme (2 nM) working solution was added to a 384-well plate; and then 0.5 μL of different concentrations of compound we...More data for this Ligand-Target Pair
Affinity DataIC50: 1.12nMAssay Description:4.5 μL of 2.2×ACC1 enzyme (2 nM) working solution was added to a 384-well plate; and then 0.5 μL of different concentrations of compound we...More data for this Ligand-Target Pair
Affinity DataIC50: 1.21nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
Affinity DataIC50: 1.22nMAssay Description:4.5 μL of 2.2×ACC1 enzyme (2 nM) working solution was added to a 384-well plate; and then 0.5 μL of different concentrations of compound we...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant human C-terminal His-tagged ACC1 (1 to 2383 residues) expressed in baculovirus infected Sf9 insect cells preincubated for 1...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of full length human recombinant ACC1 expressed in baculovirus infected Sf9 cells incubated for 18 hrs in presence of ATP by envision fluo...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of full length human recombinant ACC1 expressed in baculovirus infected Sf9 cells incubated for 18 hrs in presence of ATP by envision fluo...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 1.35nMAssay Description:4.5 μL of 2.2×ACC1 enzyme (2 nM) working solution was added to a 384-well plate; and then 0.5 μL of different concentrations of compound we...More data for this Ligand-Target Pair
Affinity DataIC50: 1.43nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
Affinity DataIC50: 1.43nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
Affinity DataIC50: 1.43nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
Affinity DataIC50: 1.48nMAssay Description:4.5 μL of 2.2×ACC1 enzyme (2 nM) working solution was added to a 384-well plate; and then 0.5 μL of different concentrations of compound we...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant human His-tagged ACC1 expressed in baculovirus infected SF9 cells using acetyl-CoA as substrate incubated for 60 mins follo...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of full length human recombinant ACC1 expressed in baculovirus infected Sf9 cells incubated for 18 hrs in presence of ATP by envision fluo...More data for this Ligand-Target Pair
Affinity DataIC50: 1.55nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
Affinity DataIC50: 1.56nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
Affinity DataIC50: 1.57nMAssay Description:4.5 μL of 2.2×ACC1 enzyme (2 nM) working solution was added to a 384-well plate; and then 0.5 μL of different concentrations of compound we...More data for this Ligand-Target Pair
Affinity DataIC50: 1.64nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
Affinity DataIC50: 1.69nMAssay Description:4.5 μL of 2.2×ACC1 enzyme (2 nM) working solution was added to a 384-well plate; and then 0.5 μL of different concentrations of compound we...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of ACC1 (unknown origin)More data for this Ligand-Target Pair
