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TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50377826(CHEMBL402979)
Affinity DataEC50: >1.00E+5nMAssay Description:Activity at NR1/NR2A receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced current responseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50377832(CHEMBL401688)
Affinity DataEC50: >1.00E+5nMAssay Description:Activity at NR1/NR2A receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced current responseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50377830(CHEMBL401806)
Affinity DataEC50: >1.00E+5nMAssay Description:Activity at NR1/NR2A receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced current responseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50203305(benzyl 4-[(pyridin-4-ylamino)methyl]piperidine-1-c...)
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at human NR2A expressed in Ltk- cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164391(CHEMBL3799162)
Affinity DataEC50:  6.22E+4nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164390(CHEMBL3799419)
Affinity DataEC50:  1.90E+3nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164402(CHEMBL3799438)
Affinity DataEC50:  4.90E+3nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164400(CHEMBL3799694)
Affinity DataEC50:  436nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164389(CHEMBL3799181)
Affinity DataEC50:  3.10E+3nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164387(CHEMBL3797392)
Affinity DataEC50:  1.70E+4nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164385(CHEMBL3798734)
Affinity DataEC50:  1.29E+4nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164384(CHEMBL3799814)
Affinity DataEC50:  1.75E+4nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164393(CHEMBL3799654)
Affinity DataEC50:  9.10E+3nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164392(CHEMBL3797818)
Affinity DataEC50:  1.20E+3nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164479(CHEMBL3799325)
Affinity DataEC50:  394nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164381(CHEMBL3800444)
Affinity DataEC50:  7.00E+3nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164379(CHEMBL3797677)
Affinity DataEC50:  1.70E+3nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164378(CHEMBL1555332)
Affinity DataEC50:  9.34E+3nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164478(CHEMBL3798041)
Affinity DataEC50:  132nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164475(CHEMBL3800406)
Affinity DataEC50:  434nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164452(CHEMBL3800614)
Affinity DataEC50:  131nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164446(CHEMBL3798502)
Affinity DataEC50:  93nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164484(CHEMBL3797659)
Affinity DataEC50:  60nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164483(CHEMBL3798757)
Affinity DataEC50:  88nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164382(CHEMBL3797850)
Affinity DataEC50:  8.50E+3nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164398(CHEMBL3799213)
Affinity DataEC50:  21nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164481(CHEMBL3799759)
Affinity DataEC50:  414nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164480(CHEMBL3799233)
Affinity DataEC50:  5.71E+4nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164486(CHEMBL3797897)
Affinity DataEC50:  536nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164380(CHEMBL3799878)
Affinity DataEC50:  30nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164477(CHEMBL3800556)
Affinity DataEC50:  18nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164460(CHEMBL3799437)
Affinity DataEC50:  73nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164451(CHEMBL3799064)
Affinity DataEC50:  900nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164444(CHEMBL3800605)
Affinity DataEC50:  454nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164485(CHEMBL3799657)
Affinity DataEC50:  24nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164482(CHEMBL3800265)
Affinity DataEC50:  382nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164397(CHEMBL3798907)
Affinity DataEC50:  2.20E+3nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164396(CHEMBL3799103)
Affinity DataEC50:  129nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164395(CHEMBL3799697)
Affinity DataEC50:  168nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164394(CHEMBL3800085)
Affinity DataEC50:  137nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164401(CHEMBL3797925)
Affinity DataEC50:  159nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164399(CHEMBL3797313)
Affinity DataEC50:  183nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164388(CHEMBL3799832)
Affinity DataEC50:  183nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164386(CHEMBL3797378)
Affinity DataEC50:  63nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164383(CHEMBL3797994)
Affinity DataEC50:  649nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164404(CHEMBL3797797)
Affinity DataEC50:  685nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164403(CHEMBL3798166)
Affinity DataEC50:  2.60E+3nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164476(CHEMBL3799732)
Affinity DataEC50:  312nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164449(CHEMBL3797274)
Affinity DataEC50:  1.90E+3nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50164405(CHEMBL3800532)
Affinity DataEC50:  900nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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