Compile Data Set for Download or QSAR
Report error Found 43 of affinity data for UniProtKB/TrEMBL: Q06830
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  46nMAssay Description:Binding affinity to human PRDX1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50651860(CHEMBL5647448)
Affinity DataIC50: 164nMAssay Description:Inhibition of PRDX1 (unknown origin) in presence of cofactor A/cofactor B/NADPH incubated for 25 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50651855(CHEMBL5647239)
Affinity DataIC50: 165nMAssay Description:Inhibition of PRDX1 (unknown origin) in presence of cofactor A/cofactor B/NADPH incubated for 25 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50651859(CHEMBL5639299)
Affinity DataIC50: 239nMAssay Description:Inhibition of PRDX1 (unknown origin) in presence of cofactor A/cofactor B/NADPH incubated for 25 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50651858(CHEMBL5647369)
Affinity DataIC50: 285nMAssay Description:Inhibition of PRDX1 (unknown origin) in presence of cofactor A/cofactor B/NADPH incubated for 25 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50644429(CHEMBL5569469)
Affinity DataIC50: 310nMAssay Description:Inhibition of recombinant PRDX1 (unknown origin) using H2O2 as substrate preincubated for 0.5 hrs followed by substrate addition by TRX-TrxR-NADPH co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50644440(CHEMBL5569818)
Affinity DataIC50: 330nMAssay Description:Inhibition of recombinant PRDX1 (unknown origin) using H2O2 as substrate preincubated for 0.5 hrs followed by substrate addition by TRX-TrxR-NADPH co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50644433(CHEMBL5572018)
Affinity DataIC50: 340nMAssay Description:Inhibition of recombinant PRDX1 (unknown origin) using H2O2 as substrate preincubated for 0.5 hrs followed by substrate addition by TRX-TrxR-NADPH co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50644435(CHEMBL5565154)
Affinity DataIC50: 350nMAssay Description:Inhibition of recombinant PRDX1 (unknown origin) using H2O2 as substrate preincubated for 0.5 hrs followed by substrate addition by TRX-TrxR-NADPH co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50644434(CHEMBL5569995)
Affinity DataIC50: 360nMAssay Description:Inhibition of recombinant PRDX1 (unknown origin) using H2O2 as substrate preincubated for 0.5 hrs followed by substrate addition by TRX-TrxR-NADPH co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50644438(CHEMBL5571353)
Affinity DataIC50: 360nMAssay Description:Inhibition of recombinant PRDX1 (unknown origin) using H2O2 as substrate preincubated for 0.5 hrs followed by substrate addition by TRX-TrxR-NADPH co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50644435(CHEMBL5565154)
Affinity DataKd:  370nMAssay Description:Binding affinity to CM5 sensor chip-immobilized recombinant PRDX1 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50644427(CHEMBL5594961)
Affinity DataIC50: 370nMAssay Description:Inhibition of recombinant PRDX1 (unknown origin) using H2O2 as substrate preincubated for 0.5 hrs followed by substrate addition by TRX-TrxR-NADPH co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50644436(CHEMBL5572187)
Affinity DataIC50: 380nMAssay Description:Inhibition of recombinant PRDX1 (unknown origin) using H2O2 as substrate preincubated for 0.5 hrs followed by substrate addition by TRX-TrxR-NADPH co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50644428(CHEMBL5591790)
Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant PRDX1 (unknown origin) using H2O2 as substrate preincubated for 0.5 hrs followed by substrate addition by TRX-TrxR-NADPH co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50644442(CHEMBL5570187)
Affinity DataIC50: 410nMAssay Description:Inhibition of recombinant PRDX1 (unknown origin) using H2O2 as substrate preincubated for 0.5 hrs followed by substrate addition by TRX-TrxR-NADPH co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50644432(CHEMBL5573037)
Affinity DataIC50: 420nMAssay Description:Inhibition of recombinant PRDX1 (unknown origin) using H2O2 as substrate preincubated for 0.5 hrs followed by substrate addition by TRX-TrxR-NADPH co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50644443(CHEMBL5566003)
Affinity DataIC50: 450nMAssay Description:Inhibition of recombinant PRDX1 (unknown origin) using H2O2 as substrate preincubated for 0.5 hrs followed by substrate addition by TRX-TrxR-NADPH co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50644441(CHEMBL5564537)
Affinity DataIC50: 460nMAssay Description:Inhibition of recombinant PRDX1 (unknown origin) using H2O2 as substrate preincubated for 0.5 hrs followed by substrate addition by TRX-TrxR-NADPH co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50644431(CHEMBL5575303)
Affinity DataIC50: 460nMAssay Description:Inhibition of recombinant PRDX1 (unknown origin) using H2O2 as substrate preincubated for 0.5 hrs followed by substrate addition by TRX-TrxR-NADPH co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50644439(CHEMBL5566476)
Affinity DataIC50: 470nMAssay Description:Inhibition of recombinant PRDX1 (unknown origin) using H2O2 as substrate preincubated for 0.5 hrs followed by substrate addition by TRX-TrxR-NADPH co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50644424(CHEMBL5572492)
Affinity DataIC50: 470nMAssay Description:Inhibition of recombinant PRDX1 (unknown origin) using H2O2 as substrate preincubated for 0.5 hrs followed by substrate addition by TRX-TrxR-NADPH co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50651862(CHEMBL5646554)
Affinity DataIC50: 481nMAssay Description:Inhibition of PRDX1 (unknown origin) in presence of cofactor A/cofactor B/NADPH incubated for 25 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50644425(CHEMBL5572158)
Affinity DataIC50: 490nMAssay Description:Inhibition of recombinant PRDX1 (unknown origin) using H2O2 as substrate preincubated for 0.5 hrs followed by substrate addition by TRX-TrxR-NADPH co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50644423(CHEMBL5532404)
Affinity DataIC50: 490nMAssay Description:Inhibition of recombinant PRDX1 (unknown origin) using H2O2 as substrate preincubated for 0.5 hrs followed by substrate addition by TRX-TrxR-NADPH co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50644444(CHEMBL5575142)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant PRDX1 (unknown origin) using H2O2 as substrate preincubated for 0.5 hrs followed by substrate addition by TRX-TrxR-NADPH co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50071058(CHEMBL301982 | cid_4274774 | (2R,4aS,6aS,12bR,14aS...)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant PRDX1 (unknown origin) using H2O2 as substrate preincubated for 0.5 hrs followed by substrate addition by TRX-TrxR-NADPH co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50651863(CHEMBL5639325)
Affinity DataIC50: 525nMAssay Description:Inhibition of PRDX1 (unknown origin) in presence of cofactor A/cofactor B/NADPH incubated for 25 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50644445(CHEMBL5571140)
Affinity DataIC50: 530nMAssay Description:Inhibition of recombinant PRDX1 (unknown origin) using H2O2 as substrate preincubated for 0.5 hrs followed by substrate addition by TRX-TrxR-NADPH co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50644426(CHEMBL5572484)
Affinity DataIC50: 540nMAssay Description:Inhibition of recombinant PRDX1 (unknown origin) using H2O2 as substrate preincubated for 0.5 hrs followed by substrate addition by TRX-TrxR-NADPH co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50644430(CHEMBL5574572)
Affinity DataIC50: 640nMAssay Description:Inhibition of recombinant PRDX1 (unknown origin) using H2O2 as substrate preincubated for 0.5 hrs followed by substrate addition by TRX-TrxR-NADPH co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50431029(CHEMBL574646)
Affinity DataIC50: 950nMAssay Description:Inhibition of PRDX1 in human PMA-differentiated LPS-stimulated THP1 cells assessed as reduction in NLRP3 inflammasome activation preincubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50651857(CHEMBL5647003)
Affinity DataIC50: 979nMAssay Description:Inhibition of PRDX1 (unknown origin) in presence of cofactor A/cofactor B/NADPH incubated for 25 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50651856(CHEMBL5647534)
Affinity DataIC50: 1.47E+3nMAssay Description:Inhibition of PRDX1 (unknown origin) in presence of cofactor A/cofactor B/NADPH incubated for 25 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50651861(CHEMBL5646385)
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of PRDX1 (unknown origin) in presence of cofactor A/cofactor B/NADPH incubated for 25 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50071058(CHEMBL301982 | cid_4274774 | (2R,4aS,6aS,12bR,14aS...)
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of PRDX1 (unknown origin) in presence of cofactor A/cofactor B/NADPH incubated for 25 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50504090(CHEMBL4092369)
Affinity DataKd:  1.83E+3nMAssay Description:Binding affinity to full-length human PRDX1 by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50651854(CHEMBL5647082)
Affinity DataIC50: 2.49E+3nMAssay Description:Inhibition of PRDX1 (unknown origin) in presence of cofactor A/cofactor B/NADPH incubated for 25 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50411905(CHEMBL272733)
Affinity DataKd:  2.61E+3nMAssay Description:Binding affinity to full-length human PRDX1 by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  9.72E+3nMAssay Description:Binding affinity to human PRDX1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50365463(CHEMBL1232461)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PRDX1 (unknown origin) incubated for 1 hr by colloidal coomassie staining based LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50651864(CHEMBL4860684)
Affinity DataIC50: 1.48E+4nMAssay Description:Inhibition of PRDX1 (unknown origin) in presence of cofactor A/cofactor B/NADPH incubated for 25 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPeroxiredoxin-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50644437(CHEMBL5569306)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant PRDX1 (unknown origin) using H2O2 as substrate preincubated for 0.5 hrs followed by substrate addition by TRX-TrxR-NADPH co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed