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Report error Found 46 of affinity data for UniProtKB/TrEMBL: Q06278
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM19441(Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human aldehyde oxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM19441(Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human aldehyde oxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50187243(ethinyloestradiol | 17alpha-ethynylestra-1,3,5(10)...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human liver AOX using phthalazine as substrate incubated for 2.5 mins by HPLC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human liver AOX using phthalazine as substrate incubated for 2.5 mins by HPLC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM19459(Prunetol | Genisteol | CHEMBL44 | US8552057, 2 | c...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human liver AOX using phthalazine as substrate incubated for 2.5 mins by HPLC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM19441(Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of human AOX using phthalazine as substrate preincubated for 30 mins followed by substrate addition by HPLC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM19441(Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...)
Affinity DataIC50: 8nMAssay Description:Inhibition of Homo sapiens (human) aldehyde oxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50130273(4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...)
Affinity DataIC50: 33nMAssay Description:Inhibition of human aldehyde oxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332780(7-Hydroxy-acridine-4-carboxylic acid (2-dimethylam...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human aldehyde oxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataIC50: 80nMAssay Description:Inhibition of human aldehyde oxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM24778(Vitamin K3 | cid_4055 | 2-methyl-1,4-dihydronaphth...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human aldehyde oxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM19459(Prunetol | Genisteol | CHEMBL44 | US8552057, 2 | c...)
Affinity DataIC50: 340nMAssay Description:Inhibition of human aldehyde oxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM20625(CHEMBL411 | Stilbestrol | 4-[(3E)-4-(4-hydroxyphen...)
Affinity DataIC50: 460nMAssay Description:Inhibition of human aldehyde oxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50187243(ethinyloestradiol | 17alpha-ethynylestra-1,3,5(10)...)
Affinity DataIC50: 570nMAssay Description:Inhibition of human aldehyde oxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50001888([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...)
Affinity DataIC50: 570nMAssay Description:Inhibition of human aldehyde oxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50001888([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...)
Affinity DataIC50: 570nMAssay Description:Inhibition of human aldehyde oxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50001888([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human liver AOX using phthalazine as substrate incubated for 2.5 mins by HPLC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50130273(4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human liver AOX using phthalazine as substrate incubated for 2.5 mins by HPLC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM87351(m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human aldehyde oxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50015214(N-(4-Hydroxy-phenyl)-acetamide | 6-chloro-2-methox...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human aldehyde oxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50240367(CHEMBL275563 | 3-hydroxy-4-methoxybenzaldehyde | 4...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human aldehyde oxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50017716(CHEMBL282567 | 2-Benzhydryl-pentanoic acid 2-dieth...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human aldehyde oxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM19441(Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...)
Affinity DataKi:  0.870nMAssay Description:Uncompetitive type inhibition of human AOX assessed as inhibition constant using nicotine-1(S)-iminium ion as substrate incubated for 2 mins by HPLC-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM19441(Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...)
Affinity DataKi:  0.870nMAssay Description:Uncompetitive type inhibition of human AOX assessed as inhibition constant using vanillin as substrate by HPLC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM19441(Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...)
Affinity DataKi:  0.870nMAssay Description:Uncompetitive type inhibition of human AOX assessed as inhibition constant using phthalazine as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM19441(Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...)
Affinity DataKi:  0.870nMAssay Description:Uncompetitive inhibition of human liver cytosolic aldehyde oxidase using phthalazine as substrate assessed as enzyme-substrate complex by Lineweaver-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM19441(Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...)
Affinity DataKi:  2.30nMAssay Description:Competitive inhibition of human liver cytosolic aldehyde oxidase using DACA as substrate assessed as free enzyme by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50187243(ethinyloestradiol | 17alpha-ethynylestra-1,3,5(10)...)
Affinity DataKi:  430nMAssay Description:Competitive inhibition of human liver cytosolic aldehyde oxidase using DACA as substrate assessed as free enzyme by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM24778(Vitamin K3 | cid_4055 | 2-methyl-1,4-dihydronaphth...)
Affinity DataKi:  470nMAssay Description:Competitive inhibition of human liver cytosolic aldehyde oxidase using DACA as substrate assessed as free enzyme by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50001888([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...)
Affinity DataKi:  620nMAssay Description:Competitive inhibition of human liver cytosolic aldehyde oxidase using DACA as substrate assessed as free enzyme by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataKi:  870nMAssay Description:Competitive inhibition of human liver cytosolic aldehyde oxidase using DACA as substrate assessed as free enzyme by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataKi:  1.20E+3nMAssay Description:Competitive inhibition of human liver cytosolic aldehyde oxidase using DACA as substrate assessed as free enzyme by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM24778(Vitamin K3 | cid_4055 | 2-methyl-1,4-dihydronaphth...)
Affinity DataKi:  1.50E+3nMAssay Description:Uncompetitive inhibition of human liver cytosolic aldehyde oxidase using DACA as substrate assessed as enzyme-substrate complex by Lineweaver-Burk pl...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50187243(ethinyloestradiol | 17alpha-ethynylestra-1,3,5(10)...)
Affinity DataKi:  3.60E+3nMAssay Description:Uncompetitive inhibition of human liver cytosolic aldehyde oxidase using DACA as substrate assessed as enzyme-substrate complex by Lineweaver-Burk pl...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataKi:  4.40E+3nMAssay Description:Uncompetitive inhibition of human liver cytosolic aldehyde oxidase using DACA as substrate assessed as enzyme-substrate complex by Lineweaver-Burk pl...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  5.10E+3nMAssay Description:Competitive inhibition of human liver cytosolic aldehyde oxidase using DACA as substrate assessed as free enzyme by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50366979(PYRIDOXAL)
Affinity DataKi:  3.00E+4nMAssay Description:Tested for its ability to inhibit rabbit liver aldehyde oxidase catalyzed oxidation of N-methyl-nicotinamide (NMN)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM86521(CAS_5719 | NSC_5719 | Zaleplon)
Affinity DataKi:  8.30E+4nMAssay Description:Inhibition of aldehyde oxidase in human liver cytosol assessed as production of oxozoniporideMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50366978(CHEMBL103375)
Affinity DataKi:  1.00E+5nMAssay Description:Tested for its ability to inhibit rabbit liver aldehyde oxidase catalyzed oxidation of N-methyl-nicotinamide (NMN)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM22889(N-methyl-N-[2-(5-methyl-1H-4-imidazolylmethylsulfa...)
Affinity DataKi:  1.55E+5nMAssay Description:Inhibition of human aldehyde oxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50366982(CHEMBL316980)
Affinity DataKi:  2.00E+5nMAssay Description:Tested for its ability to inhibit rabbit liver aldehyde oxidase catalyzed oxidation of N-methyl-nicotinamide (NMN)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50366976(CHEMBL102691)
Affinity DataKi:  2.00E+5nMAssay Description:Tested for its ability to inhibit rabbit liver aldehyde oxidase catalyzed oxidation of N-methyl-nicotinamide (NMN)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50366980(CHEMBL318466)
Affinity DataKi:  3.00E+5nMAssay Description:Tested for its ability to inhibit rabbit liver aldehyde oxidase catalyzed oxidation of N-methyl-nicotinamide (NMN)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50366977(CHEMBL103253)
Affinity DataKi:  3.00E+5nMAssay Description:Tested for its ability to inhibit rabbit liver aldehyde oxidase catalyzed oxidation of N-methyl-nicotinamide (NMN)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50366981(CHEMBL318547)
Affinity DataKi:  4.00E+5nMAssay Description:Tested for its ability to inhibit rabbit liver aldehyde oxidase catalyzed oxidation of N-methyl-nicotinamide (NMN)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldehyde oxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50366975(CHEMBL105079)
Affinity DataKi:  1.50E+6nMAssay Description:Tested for its ability to inhibit rabbit liver aldehyde oxidase catalyzed oxidation of N-methyl-nicotinamide (NMN)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed