Compile Data Set for Download or QSAR
Report error Found 136 of affinity data for UniProtKB/TrEMBL: P80276
LigandPNGBDBM50289610([3-(4,5,7-Trifluoro-benzothiazol-2-ylmethyl)-pheny...)
Affinity DataIC50: 6.60nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289614([3-Chloro-5-(4,5,7-trifluoro-benzothiazol-2-ylmeth...)
Affinity DataIC50: 7nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289613({Phenyl-[3-(4,5,7-trifluoro-benzothiazol-2-yl)-pro...)
Affinity DataIC50: 8.30nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289624({Phenyl-[3-(4,5,7-trifluoro-benzothiazol-2-yl)-thi...)
Affinity DataIC50: 8.40nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289628(3-Carboxymethyl-5-(4,5,7-trifluoro-benzothiazol-2-...)
Affinity DataIC50: 8.70nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289617([3-Fluoro-5-(4,5,7-trifluoro-benzothiazol-2-ylmeth...)
Affinity DataIC50: 8.80nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289616([2-Chloro-3-(4,5,7-trifluoro-benzothiazol-2-ylmeth...)
Affinity DataIC50: 9.30nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289621([3-Bromo-5-(4,5,7-trifluoro-benzothiazol-2-ylmethy...)
Affinity DataIC50: 9.40nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289629([3-Oxo-4-(4,5,7-trifluoro-benzothiazol-2-ylmethyl)...)
Affinity DataIC50: 9.5nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289612([3-Methyl-5-(4,5,7-trifluoro-benzothiazol-2-ylmeth...)
Affinity DataIC50: 9.60nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289625({Benzyl-[3-(4,5,7-trifluoro-benzothiazol-2-yl)-pro...)
Affinity DataIC50: 9.70nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289615([3-Iodo-5-(4,5,7-trifluoro-benzothiazol-2-ylmethyl...)
Affinity DataIC50: 11nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289620({Methyl-[3-(4,5,7-trifluoro-benzothiazol-2-yl)-thi...)
Affinity DataIC50: 11nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM16496(CHEMBL10413 | FR 74366 | [3-(4-bromo-2-fluorobenzy...)
Affinity DataIC50: 12nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article
PDB3D3D Structure (crystal)
LigandPNGBDBM50289619([3-Dimethylamino-5-(4,5,7-trifluoro-benzothiazol-2...)
Affinity DataIC50: 12nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289623({Methyl-[3-(4,5,7-trifluoro-benzothiazol-2-yl)-pro...)
Affinity DataIC50: 13nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM16314(N-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]c...)
Affinity DataIC50: 15nMAssay Description:In vitro inhibitory activity against aldose reductase in porcine lens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50067407((3R)-2'-(4-bromo-2-fluorobenzyl)-1'H,2H,5H-spiro[p...)
Affinity DataIC50: 15nMAssay Description:In vitro inhibitory activity against aldose reductase in porcine lens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM16314(N-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]c...)
Affinity DataIC50: 16nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article
PDB3D3D Structure (crystal)
LigandPNGBDBM50289626([2-(4,5,7-Trifluoro-benzothiazol-2-ylmethyl)-pheny...)
Affinity DataIC50: 19nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50009777(Ponalrestat (statil) | CHEMBL7679 | [3-(4-Bromo-2-...)
Affinity DataIC50: 21nMAssay Description:In vitro inhibitory activity against aldose reductase in porcine lens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50289611({Phenethyl-[3-(4,5,7-trifluoro-benzothiazol-2-yl)-...)
Affinity DataIC50: 21nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50067390(2'-(3,4-dichlorobenzyl)spiro[tetrahydro-1H-pyrrole...)
Affinity DataIC50: 23nMAssay Description:In vitro inhibitory activity against aldose reductase in porcine lens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50289622({Benzyl-[3-(4,5,7-trifluoro-benzothiazol-2-yl)-thi...)
Affinity DataIC50: 23nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM16314(N-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]c...)
Affinity DataIC50: 30nMAssay Description:Inhibition of aldose reductase from pig lensesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50067379(2'-(3-chlorobenzyl)spiro[tetrahydro-1H-pyrrole-3,4...)
Affinity DataIC50: 35nMAssay Description:In vitro inhibitory activity against aldose reductase in porcine lens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50067401(2'-(4-bromo-2-fluorobenzyl)-6'-chlorospiro[tetrahy...)
Affinity DataIC50: 35nMAssay Description:In vitro inhibitory activity against aldose reductase in porcine lens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50067391(2'-(2-chlorobenzyl)spiro[tetrahydro-1H-pyrrole-3,4...)
Affinity DataIC50: 37nMAssay Description:In vitro inhibitory activity against aldose reductase in porcine lens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50067409(2'-(3-bromobenzyl)spiro[tetrahydro-1H-pyrrole-3,4'...)
Affinity DataIC50: 37nMAssay Description:In vitro inhibitory activity against aldose reductase in porcine lens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50067396(2'-(4-chlorobenzyl)spiro[tetrahydro-1H-pyrrole-3,4...)
Affinity DataIC50: 38nMAssay Description:In vitro inhibitory activity against aldose reductase in porcine lens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50289618([4-(4,5,7-Trifluoro-benzothiazol-2-ylmethyl)-pheny...)
Affinity DataIC50: 38nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50067400(6'-bromo-2'-(4-bromo-2-fluorobenzyl)spiro[tetrahyd...)
Affinity DataIC50: 40nMAssay Description:In vitro inhibitory activity against aldose reductase in porcine lens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50067375(2'-(4-chloro-2-fluorobenzyl)spiro[tetrahydro-1H-py...)
Affinity DataIC50: 41nMAssay Description:In vitro inhibitory activity against aldose reductase in porcine lens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50067376(2'-(4-bromo-2-fluorobenzyl)spiro[tetrahydro-1H-pyr...)
Affinity DataIC50: 45nMAssay Description:In vitro inhibitory activity against aldose reductase in porcine lens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50067382(2'-(4-methoxybenzyl)spiro[tetrahydro-1H-pyrrole-3,...)
Affinity DataIC50: 46nMAssay Description:In vitro inhibitory activity against aldose reductase in porcine lens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50067399(2'-(4-bromobenzyl)spiro[tetrahydro-1H-pyrrole-3,4'...)
Affinity DataIC50: 47nMAssay Description:In vitro inhibitory activity against aldose reductase in porcine lens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50067402(2'-(4-bromo-2-fluorobenzyl)-7'-chlorospiro[tetrahy...)
Affinity DataIC50: 50nMAssay Description:In vitro inhibitory activity against aldose reductase in porcine lens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50289627(6-(4,5,7-Trifluoro-benzothiazol-2-yl)-hexanoic aci...)
Affinity DataIC50: 50nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50067386(2'-(4-methylbenzyl)spiro[tetrahydro-1H-pyrrole-3,4...)
Affinity DataIC50: 52nMAssay Description:In vitro inhibitory activity against aldose reductase in porcine lens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50067395(6',7'-dibromo-2'-(4-bromo-2-fluorobenzyl)spiro[tet...)
Affinity DataIC50: 52nMAssay Description:In vitro inhibitory activity against aldose reductase in porcine lens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50067413(2'-(2-bromobenzyl)spiro[tetrahydro-1H-pyrrole-3,4'...)
Affinity DataIC50: 52nMAssay Description:In vitro inhibitory activity against aldose reductase in porcine lens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50067411(2'-(2-fluorobenzyl)spiro[tetrahydro-1H-pyrrole-3,4...)
Affinity DataIC50: 61nMAssay Description:In vitro inhibitory activity against aldose reductase in porcine lens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50067387(2'-(2,4-difluorobenzyl)spiro[tetrahydro-1H-pyrrole...)
Affinity DataIC50: 72nMAssay Description:In vitro inhibitory activity against aldose reductase in porcine lens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50067414(2'-(4-trifluoromethylbenzyl)spiro[tetrahydro-1H-py...)
Affinity DataIC50: 80nMAssay Description:In vitro inhibitory activity against aldose reductase in porcine lens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50067394(2'-benzylspiro[tetrahydro-1H-pyrrole-3,4'-(1',2',3...)
Affinity DataIC50: 99nMAssay Description:In vitro inhibitory activity against aldose reductase in porcine lens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50067388(7'-bromo-2'-(4-bromo-2-fluorobenzyl)spiro[tetrahyd...)
Affinity DataIC50: 100nMAssay Description:In vitro inhibitory activity against aldose reductase in porcine lens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50067380(2'-(4-nitrobenzyl)spiro[tetrahydro-1H-pyrrole-3,4'...)
Affinity DataIC50: 110nMAssay Description:In vitro inhibitory activity against aldose reductase in porcine lens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50067381(2'-(3,4-dimethoxybenzyl)spiro[tetrahydro-1H-pyrrol...)
Affinity DataIC50: 110nMAssay Description:In vitro inhibitory activity against aldose reductase in porcine lens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50067404(2'-(4-fluorobenzyl)spiro[tetrahydro-1H-pyrrole-3,4...)
Affinity DataIC50: 120nMAssay Description:In vitro inhibitory activity against aldose reductase in porcine lens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50067398([2-(3,4-Dichloro-benzyl)-1,3-dioxo-1,2,3,4-tetrahy...)
Affinity DataIC50: 131nMAssay Description:In vitro inhibitory activity against aldose reductase in porcine lens.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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