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Report error Found 14 of affinity data for UniProtKB/TrEMBL: P78348
TargetAcid-sensing ion channel 1(Human)
Bogomoletz Institute of Physiology of Nas Ukraine

Curated by ChEMBL
LigandPNGBDBM50096642(CHEMBL3577296)
Affinity DataIC50: 27nMpH: 6.7Assay Description:Inhibition of human ASIC1a endogenously expressed in HEK293 cells clamped at -100 mV gated ionic current at pH 6.7 by standard whole cell patch clamp...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcid-sensing ion channel 1(Human)
Bogomoletz Institute of Physiology of Nas Ukraine

Curated by ChEMBL
LigandPNGBDBM50348098(CHEMBL1800430)
Affinity DataIC50: 224nMAssay Description:Inhibition of ASIC1aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcid-sensing ion channel 1(Human)
Bogomoletz Institute of Physiology of Nas Ukraine

Curated by ChEMBL
LigandPNGBDBM50408492(CHEMBL5269133)
Affinity DataIC50: 407nMAssay Description:Inhibition of human ASIC1a in HEK293 cells assessed as inward proton-gated current at pH 6.0 incubated with compound followed by PcTx1 addition by pa...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAcid-sensing ion channel 1(Human)
Bogomoletz Institute of Physiology of Nas Ukraine

Curated by ChEMBL
LigandPNGBDBM50408498(CHEMBL5270983)
Affinity DataIC50: 518nMAssay Description:Inhibition of human ASIC1a in HEK293 cells assessed as inward proton-gated current at pH 6.0 incubated with compound followed by PcTx1 addition by pa...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAcid-sensing ion channel 1(Human)
Bogomoletz Institute of Physiology of Nas Ukraine

Curated by ChEMBL
LigandPNGBDBM50408502(CHEMBL5289168)
Affinity DataIC50: 729nMAssay Description:Inhibition of human ASIC1a in HEK293 cells assessed as inward proton-gated current at pH 6.0 incubated with compound followed by PcTx1 addition by pa...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAcid-sensing ion channel 1(Human)
Bogomoletz Institute of Physiology of Nas Ukraine

Curated by ChEMBL
LigandPNGBDBM50408500(CHEMBL5278611)
Affinity DataIC50: 972nMAssay Description:Inhibition of human ASIC1a in HEK293 cells assessed as inward proton-gated current at pH 6.0 incubated with compound followed by PcTx1 addition by pa...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAcid-sensing ion channel 1(Human)
Bogomoletz Institute of Physiology of Nas Ukraine

Curated by ChEMBL
LigandPNGBDBM50408497(CHEMBL5287933)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of human ASIC1a in HEK293 cells assessed as inward proton-gated current at pH 6.0 incubated with compound followed by PcTx1 addition by pa...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAcid-sensing ion channel 1(Human)
Bogomoletz Institute of Physiology of Nas Ukraine

Curated by ChEMBL
LigandPNGBDBM50408493(CHEMBL5285672)
Affinity DataIC50: 1.99E+3nMAssay Description:Inhibition of human ASIC1a in HEK293 cells assessed as inward proton-gated current at pH 6.0 incubated with compound followed by PcTx1 addition by pa...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAcid-sensing ion channel 1(Human)
Bogomoletz Institute of Physiology of Nas Ukraine

Curated by ChEMBL
LigandPNGBDBM50408496(CHEMBL5291421)
Affinity DataIC50: 1.99E+3nMAssay Description:Inhibition of human ASIC1a in HEK293 cells assessed as inward proton-gated current at pH 6.0 incubated with compound followed by PcTx1 addition by pa...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAcid-sensing ion channel 1(Human)
Bogomoletz Institute of Physiology of Nas Ukraine

Curated by ChEMBL
LigandPNGBDBM50408495(CHEMBL5267130)
Affinity DataIC50: 2.59E+3nMAssay Description:Inhibition of human ASIC1a in HEK293 cells assessed as inward proton-gated current at pH 6.0 incubated with compound followed by PcTx1 addition by pa...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAcid-sensing ion channel 1(Human)
Bogomoletz Institute of Physiology of Nas Ukraine

Curated by ChEMBL
LigandPNGBDBM50408499(CHEMBL5276647)
Affinity DataIC50: 2.95E+3nMAssay Description:Inhibition of human ASIC1a in HEK293 cells assessed as inward proton-gated current at pH 6.0 incubated with compound followed by PcTx1 addition by pa...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAcid-sensing ion channel 1(Human)
Bogomoletz Institute of Physiology of Nas Ukraine

Curated by ChEMBL
LigandPNGBDBM50408494(CHEMBL5267106)
Affinity DataIC50: 3.14E+3nMAssay Description:Inhibition of human ASIC1a in HEK293 cells assessed as inward proton-gated current at pH 6.0 incubated with compound followed by PcTx1 addition by pa...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAcid-sensing ion channel 1(Human)
Bogomoletz Institute of Physiology of Nas Ukraine

Curated by ChEMBL
LigandPNGBDBM50096642(CHEMBL3577296)
Affinity DataIC50: 7.34E+3nMpH: 5.0Assay Description:Inhibition of human ASIC1a endogenously expressed in HEK293 cells clamped at -100 mV gated ionic current at pH 5.0 by standard whole cell patch clamp...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcid-sensing ion channel 1(Human)
Bogomoletz Institute of Physiology of Nas Ukraine

Curated by ChEMBL
LigandPNGBDBM50408501(CHEMBL5283083)
Affinity DataIC50: 9.54E+3nMAssay Description:Inhibition of human ASIC1a in HEK293 cells assessed as inward proton-gated current at pH 6.0 incubated with compound followed by PcTx1 addition by pa...More data for this Ligand-Target Pair
In DepthDetails
PubMed