Compile Data Set for Download or QSAR
Report error Found 9 of affinity data for UniProtKB/TrEMBL: P68431
TargetHistone H3.1(Human)
Mei Pharma

US Patent
LigandPNGBDBM50248375(US8551988, 2 | CHEMBL491688 | N-hydroxy-3-(2-phene...)
Affinity DataEC50:  1.70E+3nMAssay Description:To determine EC50 where acetylated histone 3 was induced by 50%, Colo205 cells was cultivated in 96 well plate at 1.5×105 cells/well for 24 h. Colo20...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone H3.1(Human)
Mei Pharma

US Patent
LigandPNGBDBM50248570(CHEMBL460963 | US8551988, 17 | 3-(1-(3-(dimethylam...)
Affinity DataEC50:  1.10E+3nMAssay Description:To determine EC50 where acetylated histone 3 was induced by 50%, Colo205 cells was cultivated in 96 well plate at 1.5×105 cells/well for 24 h. Colo20...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone H3.1(Human)
Mei Pharma

US Patent
LigandPNGBDBM50248522(CHEMBL489332 | US8551988, 67 | N-hydroxy-3-(2-phen...)
Affinity DataEC50:  500nMAssay Description:To determine EC50 where acetylated histone 3 was induced by 50%, Colo205 cells was cultivated in 96 well plate at 1.5×105 cells/well for 24 h. Colo20...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone H3.1 [22-45](Human)
Epizyme

US Patent
LigandPNGBDBM155253(US9006242, 1 | US10098888, Compound 1)
Affinity DataIC50: 5nMAssay Description:General Materials. S-adenosylmethionine (SAM), S-adenosylhomocyteine (SAH), bicine, KCI, Tween20, dimethylsulfoxide (DMSO) and bovine skin gelatin (B...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone H3.1 [22-45](Human)
Epizyme

US Patent
LigandPNGBDBM155255(US9006242, 105 | US10098888, Compound 105 | US1164...)
Affinity DataIC50: 8.40nMAssay Description:General Materials. S-adenosylmethionine (SAM), S-adenosylhomocyteine (SAH), bicine, KCI, Tween20, dimethylsulfoxide (DMSO) and bovine skin gelatin (B...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone H3.1 [22-45](Human)
Epizyme

US Patent
LigandPNGBDBM155254(US9006242, 2 | US10098888, Compound 2)
Affinity DataIC50: 15nMAssay Description:General Materials. S-adenosylmethionine (SAM), S-adenosylhomocyteine (SAH), bicine, KCI, Tween20, dimethylsulfoxide (DMSO) and bovine skin gelatin (B...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone H3.1 [22-45](Human)
Epizyme

US Patent
LigandPNGBDBM155253(US9006242, 1 | US10098888, Compound 1)
Affinity DataIC50: 77nMAssay Description:General Materials. S-adenosylmethionine (SAM), S-adenosylhomocyteine (SAH), bicine, KCI, Tween20, dimethylsulfoxide (DMSO) and bovine skin gelatin (B...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone H3.1 [22-45](Human)
Epizyme

US Patent
LigandPNGBDBM155255(US9006242, 105 | US10098888, Compound 105 | US1164...)
Affinity DataIC50: 104nMAssay Description:General Materials. S-adenosylmethionine (SAM), S-adenosylhomocyteine (SAH), bicine, KCI, Tween20, dimethylsulfoxide (DMSO) and bovine skin gelatin (B...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone H3.1 [22-45](Human)
Epizyme

US Patent
LigandPNGBDBM155254(US9006242, 2 | US10098888, Compound 2)
Affinity DataIC50: 110nMAssay Description:General Materials. S-adenosylmethionine (SAM), S-adenosylhomocyteine (SAH), bicine, KCI, Tween20, dimethylsulfoxide (DMSO) and bovine skin gelatin (B...More data for this Ligand-Target Pair
In DepthDetails
US Patent