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TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50182491(CHEBI:69015 | Malabaricone C)
Affinity DataIC50: 300nMAssay Description:Inhibition of Streptococcus pneumoniae sialidase NanA using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60 mins by FRET a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50182486(MALABARICONE B)
Affinity DataIC50: 400nMAssay Description:Inhibition of Streptococcus pneumoniae sialidase NanA using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60 mins by FRET a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50303147((-)-licarin B | CHEMBL578403)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Streptococcus pneumoniae sialidase NanA using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60 mins by FRET a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50242962(CHEMBL4079519)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of Streptococcus pneumoniae sialidase NanA using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60 mins by FRET a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50242964(CHEMBL4072450)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Streptococcus pneumoniae sialidase NanA using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60 mins by FRET a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM4706(2,3-didehydro-2-deoxy-N-acetylneuraminic acid | (2...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of Streptococcus pneumoniae sialidase NanA using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60 mins by FRET a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50242963(CHEBI:86562 | Methoxyeugenol)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of Streptococcus pneumoniae sialidase NanA using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60 mins by FRET a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50303149(Licarin A | (-)-licarin A | CHEMBL463526)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of Streptococcus pneumoniae sialidase NanA using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60 mins by FRET a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM4706(2,3-didehydro-2-deoxy-N-acetylneuraminic acid | (2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Streptococcus pneumoniae NanA using Neu5Acalpha2-3GalbetapNP as substrate after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50242967(CHEMBL4085435)
Affinity DataIC50: 2.56E+4nMAssay Description:Inhibition of Streptococcus pneumoniae sialidase NanA using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60 mins by FRET a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50242959(CHEMBL3601519)
Affinity DataIC50: 3.72E+4nMAssay Description:Inhibition of Streptococcus pneumoniae sialidase NanA using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60 mins by FRET a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50242961(CHEMBL4091275)
Affinity DataIC50: 4.42E+4nMAssay Description:Inhibition of Streptococcus pneumoniae sialidase NanA using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60 mins by FRET a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50331692((2R,3R,4S)-3-acetamido-2-((1R,2R)-3-azido-1,2-dihy...)
Affinity DataIC50: 4.43E+4nMAssay Description:Inhibition of Streptococcus pneumoniae NanA using Neu5Acalpha2-3GalbetapNP as substrate after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50466472(CHEMBL4289476)
Affinity DataIC50: 6.56E+4nMAssay Description:Inhibition of Streptococcus pneumoniae NanA using Neu5Acalpha2-3GalbetapNP as substrate after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50466474(CHEMBL4282280)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Streptococcus pneumoniae NanA using Neu5Acalpha2-3GalbetapNP as substrate after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50466473(CHEMBL4278803)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Streptococcus pneumoniae NanA using Neu5Acalpha2-3GalbetapNP as substrate after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50242966(CHEBI:68234 | Myristicin | ELEMICIN)
Affinity DataIC50: 1.97E+5nMAssay Description:Inhibition of Streptococcus pneumoniae sialidase NanA using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60 mins by FRET a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50242968(CHEMBL4097551)
Affinity DataIC50: 2.95E+5nMAssay Description:Inhibition of Streptococcus pneumoniae sialidase NanA using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60 mins by FRET a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50467188(CHEMBL4295254)
Affinity DataIC50: 1.41E+6nMAssay Description:Inhibition of Streptococcus pneumoniae neuraminidase A using MuNANA as substrate pretreated for 10 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50182491(CHEBI:69015 | Malabaricone C)
Affinity DataKi:  100nMAssay Description:Competitive inhibition of Streptococcus pneumoniae sialidase NanA using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50182486(MALABARICONE B)
Affinity DataKi:  500nMAssay Description:Competitive inhibition of Streptococcus pneumoniae sialidase NanA using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50303147((-)-licarin B | CHEMBL578403)
Affinity DataKi:  1.30E+3nMAssay Description:Noncompetitive inhibition of Streptococcus pneumoniae sialidase NanA using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM4706(2,3-didehydro-2-deoxy-N-acetylneuraminic acid | (2...)
Affinity DataKi:  1.60E+3nMpH: 9.0Assay Description:Briefly, the reaction mixtures containing the substrates and up to 100 nM sialidase were incubated at 37°C and stopped by the addition of 0.5 M Na2CO...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM4994(CHEMBL674 | (3R,4R,5S)-5-amino-4-acetamido-3-(pent...)
Affinity DataKi:  1.77E+3nMpH: 9.0Assay Description:Briefly, the reaction mixtures containing the substrates and up to 100 nM sialidase were incubated at 37°C and stopped by the addition of 0.5 M Na2CO...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50242962(CHEMBL4079519)
Affinity DataKi:  3.00E+3nMAssay Description:Noncompetitive inhibition of Streptococcus pneumoniae sialidase NanA using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50242963(CHEBI:86562 | Methoxyeugenol)
Affinity DataKi:  4.20E+3nMAssay Description:Noncompetitive inhibition of Streptococcus pneumoniae sialidase NanA using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50242964(CHEMBL4072450)
Affinity DataKi:  4.90E+3nMAssay Description:Noncompetitive inhibition of Streptococcus pneumoniae sialidase NanA using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50303149(Licarin A | (-)-licarin A | CHEMBL463526)
Affinity DataKi:  9.40E+3nMAssay Description:Noncompetitive inhibition of Streptococcus pneumoniae sialidase NanA using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50242967(CHEMBL4085435)
Affinity DataKi:  1.51E+4nMAssay Description:Noncompetitive inhibition of Streptococcus pneumoniae sialidase NanA using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50242959(CHEMBL3601519)
Affinity DataKi:  2.19E+4nMAssay Description:Noncompetitive inhibition of Streptococcus pneumoniae sialidase NanA using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50242961(CHEMBL4091275)
Affinity DataKi:  4.75E+4nMAssay Description:Noncompetitive inhibition of Streptococcus pneumoniae sialidase NanA using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM4934((2R,3R,4S)-4-carbamimidamido-3-acetamido-2-[(1R,2R...)
Affinity DataKi:  7.20E+5nMpH: 9.0Assay Description:Briefly, the reaction mixtures containing the substrates and up to 100 nM sialidase were incubated at 37°C and stopped by the addition of 0.5 M Na2CO...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed