Compile Data Set for Download or QSAR
Report error Found 117 of affinity data for UniProtKB/TrEMBL: P56719
TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM97406(Orexin receptor antagonist 1 | US20130102619, 1)
Affinity DataIC50: 12nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM97397(Orexin receptor antagonist 7 | Orexin receptor ant...)
Affinity DataIC50: 12nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM97373(Orexin receptor antagonist 5 | US20130102619, 5)
Affinity DataIC50: 17nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM97397(Orexin receptor antagonist 7 | Orexin receptor ant...)
Affinity DataIC50: 17nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM97408(Orexin receptor antagonist 3 | US20130102619, 3)
Affinity DataIC50: 18nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM97375(Orexin receptor antagonist 6 | US20130102619, 6)
Affinity DataIC50: 18nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM97378(Orexin receptor antagonist 9 | US20130102619, 9)
Affinity DataIC50: 22nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM97390(Orexin receptor antagonist 22 | US20130102619, 22)
Affinity DataIC50: 23nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM97407(Orexin receptor antagonist 2 | US20130102619, 2)
Affinity DataIC50: 28nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM97374(Orexin receptor antagonist 4 | US20130102619, 4)
Affinity DataIC50: 29nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM97377(Orexin receptor antagonist 8 | US20130102619, 8)
Affinity DataIC50: 29nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM97379(Orexin receptor antagonist 10 | US20130102619, 10)
Affinity DataIC50: 29nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM97403(Orexin receptor antagonist 35 | US20130102619, 35)
Affinity DataIC50: 31nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM97399(Orexin receptor antagonist 31 | US20130102619, 31)
Affinity DataIC50: 38nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM97400(Orexin receptor antagonist 32 | US20130102619, 32)
Affinity DataIC50: 44nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM97404(Orexin receptor antagonist 36 | US20130102619, 36)
Affinity DataIC50: 47nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM97402(Orexin receptor antagonist 34 | US20130102619, 34)
Affinity DataIC50: 48nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM97401(Orexin receptor antagonist 33 | US20130102619, 33)
Affinity DataIC50: 52nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM97384(Orexin receptor antagonist 15 | US20130102619, 15)
Affinity DataIC50: 62nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM97383(Orexin receptor antagonist 14 | US20130102619, 14)
Affinity DataIC50: 65nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM97388(Orexin receptor antagonist 20 | US20130102619, 20)
Affinity DataIC50: 67nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM97385(Orexin receptor antagonist 17 | US20130102619, 17)
Affinity DataIC50: 82nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM97398(Orexin receptor antagonist 30 | US20130102619, 30)
Affinity DataIC50: 110nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM50060937(CHEMBL3394848)
Affinity DataIC50: 1.31E+3nMAssay Description:Antagonist activity at rat OX2 receptor assessed as inhibition of Ala-6,12 orexin-A-induced calcium increase preincubated for 5 mins prior to Ala-6,1...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM50203731(CHEMBL3973097)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at rat OX2 receptor assessed as inhibition of Ala-6,12 orexin-A-induced calcium increase preincubated for 5 mins prior to Ala-6,1...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM50417257(SB-649868)
Affinity DataKi:  0.0776nMAssay Description:Antagonist activity at recombinant rat OX2R expressed in CHO cells by FLIPR calcium based functional assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM104700(US8569311, 1-10)
Affinity DataKi:  0.0800nMAssay Description:Radioligand binding assay described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM104689(US8569311, A-9)
Affinity DataKi:  0.240nMAssay Description:Radioligand binding assay described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM104697(US8569311, 1-1)
Affinity DataKi:  0.240nMAssay Description:Radioligand binding assay described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM104692(US8569311, E-5)
Affinity DataKi:  0.310nMAssay Description:Radioligand binding assay described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM104701(US8569311, 1-15)
Affinity DataKi:  0.350nMAssay Description:Radioligand binding assay described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM104698(US8569311, 1-4)
Affinity DataKi:  0.370nMAssay Description:Radioligand binding assay described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM104703(US8569311, 1-21)
Affinity DataKi:  0.480nMAssay Description:Radioligand binding assay described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM104699(US8569311, 1-8)
Affinity DataKi:  0.5nMAssay Description:Radioligand binding assay described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM104702(US8569311, 1-19)
Affinity DataKi:  0.530nMAssay Description:Radioligand binding assay described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM104690(US8569311, B-3)
Affinity DataKi:  0.540nMAssay Description:Radioligand binding assay described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM104691(US8569311, C-4)
Affinity DataKi:  0.670nMAssay Description:Radioligand binding assay described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM104706(US8569311, 1-28)
Affinity DataKi:  0.670nMAssay Description:Radioligand binding assay described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM104707(US8569311, 1-34)
Affinity DataKi:  0.680nMAssay Description:Radioligand binding assay described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM104708(US8569311, 1-37)
Affinity DataKi:  1.5nMAssay Description:Radioligand binding assay described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM104694(US8569311, G-1)
Affinity DataKi:  1.70nMAssay Description:Radioligand binding assay described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM104704(US8569311, 1-24)
Affinity DataKi:  1.70nMAssay Description:Radioligand binding assay described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM104709(US8569311, 1-38)
Affinity DataKi:  1.90nMAssay Description:Radioligand binding assay described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM104696(US8569311, I-7)
Affinity DataKi:  2nMAssay Description:Radioligand binding assay described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM50097380(CHEMBL3586432)
Affinity DataKi:  2nMAssay Description:Binding affinity to rat OX2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM104710(US8569311, 1-42)
Affinity DataKi:  3.80nMAssay Description:Radioligand binding assay described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM50097388(CHEMBL3586426)
Affinity DataKi:  7nMAssay Description:Binding affinity to rat OX2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM104705(US8569311, 1-27)
Affinity DataKi:  10nMAssay Description:Radioligand binding assay described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM50092812(CHEMBL3586433)
Affinity DataKi:  10nMAssay Description:Binding affinity to rat OX2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandPNGBDBM50092814(CHEMBL3586436)
Affinity DataKi:  10nMAssay Description:Binding affinity to rat OX2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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