Compile Data Set for Download or QSAR
Report error Found 92 of affinity data for UniProtKB/TrEMBL: P51114
TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665661(US20240116912, Example 40 | 5-(5-(4-((5-cyclopropy...)
Affinity DataEC50:  76nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665672(US20240116912, Example 51 | 5-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  325nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665671(US20240116912, Example 50 | 3-(4-((1R,F,5S)-3-((5-...)
Affinity DataEC50:  3.20nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665670(US20240116912, Example 49 | 3-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  11.7nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665669(US20240116912, Example 48 | 5-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  41.6nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665668(US20240116912, Example 47 | 3-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  3.70nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665667(US20240116912, Example 46 | 6-(5-(4-((5-cyclopropy...)
Affinity DataEC50:  74.6nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665666(US20240116912, Example 45 | 3-(5-(4-((5-cyclopropy...)
Affinity DataEC50:  610nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665665(US20240116912, Example 44 | 3-(4-(4-((3-(2-chlorop...)
Affinity DataEC50:  21.3nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665664(US20240116912, Example 43 | 6-(6-(4-((5-cyclopropy...)
Affinity DataEC50:  11.2nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665663(US20240116912, Example 42 | 3-(3-(4-((5-cyclopropy...)
Affinity DataEC50:  139nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665662(US20240116912, Example 41 | 6-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  58.4nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665673(US20240116912, Example 52 | 5-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  143nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665660(US20240116912, Example 39 | 3-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  16.1nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665659(US20240116912, Example 38 | 3-(5-(4-((5-cyclopropy...)
Affinity DataEC50:  28.6nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665658(US20240116912, Example 37 | 5-(6-(4-((5-cyclopropy...)
Affinity DataEC50:  49.4nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665657(US20240116912, Example 36 | 3-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  18.8nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665656(US20240116912, Example 35 | 3-(5-(4-((5-cyclopropy...)
Affinity DataEC50:  43.5nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665655(US20240116912, Example 34 | 3-(4-((3R,4R)-4-((5-cy...)
Affinity DataEC50:  153nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665654(US20240116912, Example 33 | 3-(4-((3S,4S)-4-((5-cy...)
Affinity DataEC50:  142nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665653(US20240116912, Example 32 | 3-(4-((3S,4R)-4-((5-cy...)
Affinity DataEC50:  12.6nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665652(US20240116912, Example 31 | 3-(4-((3R,4S)-4-((5-cy...)
Affinity DataEC50:  45nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665651(US20240116912, Example 30 | 3-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  296nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665684(US20240116912, Example 63 | 3-(6-(4-((5-cyclopropy...)
Affinity DataEC50:  215nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665695(US20240116912, Example 74 | 3-(6-(4-((5-cyclopropy...)
Affinity DataEC50:  107nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665694(US20240116912, Example 73 | 3-(6-((2R,4R)-4-((5-cy...)
Affinity DataEC50:  47.6nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665693(US20240116912, Example 72 | 3-(6-((2R,4R)-4-((3-(2...)
Affinity DataEC50:  4.5nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665692(US20240116912, Example 71 | 3-(6-((2R,4R)-4-((5-cy...)
Affinity DataEC50:  2.10nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665691(US20240116912, Example 70 | 3-(3-(4-((5-cyclopropy...)
Affinity DataEC50:  233nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665690(US20240116912, Example 69 | 5-(6-((1R,3R,5S)-3-((5...)
Affinity DataEC50:  9.5nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665689(US20240116912, Example 68 | 5-(6-((1R,3R,5S)-3-((5...)
Affinity DataEC50:  26.4nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665688(US20240116912, Example 67 | 6-(4-((1R,3R,5S)-3-((5...)
Affinity DataEC50:  12.7nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665687(US20240116912, Example 66 | 3-(6-((1R,3r,5S)-3-((5...)
Affinity DataEC50:  3nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665686(US20240116912, Example 65 | 5-(4-((1R,3R,5S)-3-((5...)
Affinity DataEC50:  22.1nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665685(US20240116912, Example 64 | 3-(6-(4-((5-cyclopropy...)
Affinity DataEC50:  70nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665650(US20240116912, Example 29 | 3-(2-(4-((5-cyclopropy...)
Affinity DataEC50:  231nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665683(US20240116912, Example 62 | 4-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  6.35E+3nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665682(US20240116912, Example 61 | 5-(6-(4-((5-cyclopropy...)
Affinity DataEC50:  298nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665681(US20240116912, Example 60 | 5-(6-(4-((5-cyclopropy...)
Affinity DataEC50:  104nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665680(US20240116912, Example 59 | 5-(6-(4-((5-cyclopropy...)
Affinity DataEC50:  17.9nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665679(US20240116912, Example 58 | 3-(3-(4-((5-cyclopropy...)
Affinity DataEC50:  421nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665678(US20240116912, Example 57 | 6-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  84.7nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665677(US20240116912, Example 56 | 3-(5-(4-((5-cyclopropy...)
Affinity DataEC50:  43.1nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665676(US20240116912, Example 55 | 3-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  174nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665675(US20240116912, Example 54 | 3-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  37.6nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665674(US20240116912, Example 53 | 3-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  9nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandPNGBDBM504310(3α,7α,11β-trihydroxy-6α-ethyl-...)
Affinity DataEC50:  42nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665626(US20240116912, Example 5 | 3-(2-(4-((5-cyclopropyl...)
Affinity DataEC50:  31nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665625(US20240116912, Example 4 | 4-(6-(4-((5-cyclopropyl...)
Affinity DataEC50:  220nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665624(US20240116912, Example 3 | 3-(4-(4-((5-cyclopropyl...)
Affinity DataEC50:  3.60nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

Displayed 1 to 50 (of 92 total ) | Next | Last >>
Jump to: