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LigandPNGBDBM50473314(CHEMBL553068)
Affinity DataIC50: 51nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50081891(1-[2-(3,3-Diphenyl-propoxy)-ethyl]-piperidine-3-ca...)
Affinity DataIC50: 55nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50473316(CHEMBL545694)
Affinity DataIC50: 68nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50473312(CHEMBL543108)
Affinity DataIC50: 74nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50080346((R)-1-(2-Benzhydrylideneaminooxy-ethyl)-piperidine...)
Affinity DataIC50: 82nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50081888((R)-1-[2-(2-Diphenylamino-ethoxy)-ethyl]-piperidin...)
Affinity DataIC50: 90nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50473321(CHEMBL563076)
Affinity DataIC50: 105nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50437146(CHEMBL1189315)
Affinity DataIC50: 184nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50473306(CHEMBL556178)
Affinity DataIC50: 248nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50473319(CHEMBL555856)
Affinity DataIC50: 265nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50437144(CHEMBL1190271)
Affinity DataIC50: 308nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50003634(1-(4,4-Diphenyl-but-3-enyl)-piperidine-3-carboxyli...)
Affinity DataIC50: 330nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50473315(CHEMBL541561)
Affinity DataIC50: 460nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50473313(CHEMBL545690)
Affinity DataIC50: 561nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50473311(CHEMBL543342)
Affinity DataIC50: 644nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50437145(CHEMBL1196076)
Affinity DataIC50: 647nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50473317(CHEMBL553053)
Affinity DataIC50: 696nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50473320(CHEMBL545452)
Affinity DataIC50: 770nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50473309(CHEMBL552675)
Affinity DataIC50: 851nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50473302(CHEMBL555631)
Affinity DataIC50: 1.16E+3nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50473303(CHEMBL542641)
Affinity DataIC50: 1.20E+3nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50003653(CHEMBL542610 | 1-(2-Benzhydryloxy-ethyl)-piperidin...)
Affinity DataIC50: 1.37E+3nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | cid_119 | Gamma-A...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of high affinity neuronal GABA uptake by synaptosomes of rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50226144(CHEBI:64307 | 2,4-Diamino-Butyric Acid | DL-2,4-di...)
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro inhibition of rat neuronal (synaptosomal) GABA uptake.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | cid_119 | Gamma-A...)
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro effect on GABA uptake in a crude preparation of synaptosomes from rat brain.More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50078167(CHEMBL69064)
Affinity DataIC50: 2.02E+3nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50473308(CHEMBL541821)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50473305(CHEMBL71789)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | cid_119 | Gamma-A...)
Affinity DataIC50: 3.00E+3nMAssay Description:In vitro inhibition of GABA uptake in rat brain synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50473318(CHEMBL539773)
Affinity DataIC50: 5.51E+3nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50003624(Nipecotic | Piperidine-3-carboxylic acid(nipecotic...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of high affinity neuronal GABA uptake by synaptosomes of rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50223874(CHEMBL277372)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of high affinity neuronal GABA uptake by synaptosomes of rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50473310(CHEMBL303402)
Affinity DataIC50: 1.36E+4nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50473307(CHEMBL545692)
Affinity DataIC50: 1.46E+4nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50021186(CHEMBL296263 | S(+)-4-amino-3-hydroxybutanoic acid...)
Affinity DataIC50: 2.90E+4nMAssay Description:In vitro inhibition of GABA uptake in rat brain synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50473304(CHEMBL541556)
Affinity DataIC50: 4.00E+4nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50021187(R(-)-4-amino-3-hydroxybutanoic acid | CHEMBL290216...)
Affinity DataIC50: 6.70E+4nMAssay Description:In vivo inhibition of GABA uptake in rat brain synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50021189(CHEMBL40804 | 5-Aminomethyl-4,5-dihydro-isoxazol-3...)
Affinity DataIC50: 7.00E+4nMAssay Description:In vivo inhibition of GABA uptake in rat brain synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50226141(CHEMBL309688)
Affinity DataIC50: 1.30E+5nMAssay Description:In vitro inhibition of rat neuronal (synaptosomal) GABA uptake.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50225363(CHEMBL40363)
Affinity DataIC50: 1.30E+5nMAssay Description:In vitro inhibition of GABA uptake in rat brain synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50021262(4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridin-5-ium-3-...)
Affinity DataIC50: 1.60E+5nMAssay Description:In vitro effect on GABA uptake in a crude preparation of synaptosomes from rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50226145(CHEMBL150830)
Affinity DataIC50: 1.60E+5nMAssay Description:In vitro inhibition of rat neuronal (synaptosomal) GABA uptake.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50223872(CHEMBL15851)
Affinity DataIC50: 1.73E+5nMAssay Description:Inhibition of high affinity neuronal GABA uptake by synaptosomes of rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50223876(CHEMBL16226)
Affinity DataIC50: 2.03E+5nMAssay Description:Inhibition of high affinity neuronal GABA uptake by synaptosomes of rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50224812(CHEBI:35010 | CHEMBL170539)
Affinity DataIC50: 2.20E+5nMAssay Description:In vitro effect on GABA uptake in a crude preparation of synaptosomes from rat brain.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50224810(CHEMBL171241)
Affinity DataIC50: 2.30E+5nMAssay Description:In vitro effect on GABA uptake in a crude preparation of synaptosomes from rat brain.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50223871(CHEMBL429974)
Affinity DataIC50: 2.40E+5nMAssay Description:Inhibition of high affinity neuronal GABA uptake by synaptosomes of rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50000106(Piperidine-4-carboxylic acid | Piperidine-4-carbox...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of high affinity neuronal GABA uptake by synaptosomes of rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50223877(CHEMBL16132)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of high affinity neuronal GABA uptake by synaptosomes of rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50223875(CHEMBL280511)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of high affinity neuronal GABA uptake by synaptosomes of rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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