Affinity DataEC50: 2.20E+4nMAssay Description:Inhibition of NGF-induced TrkA auto-phosphorylation in rat PC12 cells incubated for 15 mins by chemiluminescence based methodMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Antagonist activity at unphosphorylated rat TrkA expressed in baculovirus expression system preincubated for 20 mins followed by TK-substrate-Biotin ...More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of TrkA in rat PC12 cells assessed as reduction in beta-NGF-induced neurite outgrowth preincubated for 30 mins followed by beta-NGF stimul...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 57nMAssay Description:Antagonist activity at TrkA in rat DRG assessed as inhibition of NGF-induced ERK phosphorylation preincubated for 60 mins followed by NGF addition an...More data for this Ligand-Target Pair
Affinity DataIC50: 429nMAssay Description:Inhibition of TrkA in rat PC12 cells assessed as reduction in beta-NGF-induced neurite outgrowth incubated for 7 days by live cell imaging analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 5.88E+3nMAssay Description:Inhibition of binding of [125I]-NGF to TrkA in rat PC12 cells incubated for 2 hrs by gamma counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TrkA in rat PC12 cells assessed as reduction in beta-NGF-induced neurite outgrowth incubated for 7 days by live cell imaging analysisMore data for this Ligand-Target Pair
