Compile Data Set for Download or QSAR
Report error Found 44 for UniProtKB: P28471
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataEC50:  150nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha4beta3delta expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50273002(5-Aminomethyl-3H-[1,3,4]oxadiazol-2-one Hydrochlor...)
Affinity DataEC50:  1.28E+5nMAssay Description:Agonist activity at rat recombinant GABAA alpha-4-beta-3-gamma-2 receptor expressed in HEK293 cells assessed as normalization of GABA-induced current...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457445(CHEMBL4212818)
Affinity DataEC50:  970nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha4beta3delta expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataEC50:  60nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha4beta3 expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM235902(US9365502, MQ-87)
Affinity DataIC50: 14nMAssay Description:The IC50 values for non-competitive displacers of [35S]-TBPS from the picrotoxin binding site on GABAA receptors.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM235905(US9365502, MQ-85)
Affinity DataIC50: 29nMAssay Description:The IC50 values for non-competitive displacers of [35S]-TBPS from the picrotoxin binding site on GABAA receptors.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM235901(US9365502, MQ-86)
Affinity DataIC50: 43nMAssay Description:The IC50 values for non-competitive displacers of [35S]-TBPS from the picrotoxin binding site on GABAA receptors.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM235900(US9365502, MQ-37)
Affinity DataIC50: 46nMAssay Description:The IC50 values for non-competitive displacers of [35S]-TBPS from the picrotoxin binding site on GABAA receptors.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM235898(US9365502, MQ-38)
Affinity DataIC50: 52nMAssay Description:The IC50 values for non-competitive displacers of [35S]-TBPS from the picrotoxin binding site on GABAA receptors.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM235894(US9365502, MQ-31)
Affinity DataIC50: 61nMAssay Description:The IC50 values for non-competitive displacers of [35S]-TBPS from the picrotoxin binding site on GABAA receptors.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM235897(US9365502, MQ-33)
Affinity DataIC50: 62nMAssay Description:The IC50 values for non-competitive displacers of [35S]-TBPS from the picrotoxin binding site on GABAA receptors.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM235907(US9365502, MQ-39)
Affinity DataIC50: 65nMAssay Description:The IC50 values for non-competitive displacers of [35S]-TBPS from the picrotoxin binding site on GABAA receptors.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM235896(US9365502, MQ-32)
Affinity DataIC50: 147nMAssay Description:The IC50 values for non-competitive displacers of [35S]-TBPS from the picrotoxin binding site on GABAA receptors.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM235904(US9365502, MQ-48)
Affinity DataIC50: 282nMAssay Description:The IC50 values for non-competitive displacers of [35S]-TBPS from the picrotoxin binding site on GABAA receptors.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataIC50: 510nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha4beta3delta expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM235899(US9365502, MQ-83)
Affinity DataIC50: 748nMAssay Description:The IC50 values for non-competitive displacers of [35S]-TBPS from the picrotoxin binding site on GABAA receptors.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM235910(US9365502, MQ-50)
Affinity DataIC50: 1.06E+3nMAssay Description:The IC50 values for non-competitive displacers of [35S]-TBPS from the picrotoxin binding site on GABAA receptors.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM235903(US9365502, MQ-47)
Affinity DataIC50: 1.33E+3nMAssay Description:The IC50 values for non-competitive displacers of [35S]-TBPS from the picrotoxin binding site on GABAA receptors.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM235906(US9365502, MQ-49)
Affinity DataIC50: 1.58E+3nMAssay Description:The IC50 values for non-competitive displacers of [35S]-TBPS from the picrotoxin binding site on GABAA receptors.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM235895(US9365502, MQ-36)
Affinity DataIC50: 1.73E+3nMAssay Description:The IC50 values for non-competitive displacers of [35S]-TBPS from the picrotoxin binding site on GABAA receptors.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataIC50: 1.86E+3nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha4beta3 expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting analy...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM235911(US9365502, MQ-54)
Affinity DataIC50: 1.99E+3nMAssay Description:The IC50 values for non-competitive displacers of [35S]-TBPS from the picrotoxin binding site on GABAA receptors.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataIC50: 3.29E+3nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha4beta3gamma2 expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM235908(US9365502, MQ-53)
Affinity DataIC50: 3.63E+3nMAssay Description:The IC50 values for non-competitive displacers of [35S]-TBPS from the picrotoxin binding site on GABAA receptors.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM235909(US9365502, MQ-51)
Affinity DataIC50: 5.86E+3nMAssay Description:The IC50 values for non-competitive displacers of [35S]-TBPS from the picrotoxin binding site on GABAA receptors.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM26267(RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...)
Affinity DataKi:  3.40nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50044941(CHEMBL6421 | ZG 234 | 8-Azido-5-methyl-6-oxo-5,6-d...)
Affinity DataKi:  5.20nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50034835(Ro-19-4603 | CHEMBL269366 | Ro 19-4603 | 5-Methyl-...)
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM84956(2-(4-Methoxy-phenyl)-2,5-dihydro-pyrazolo[4,3-c]qu...)
Affinity DataKi:  6.80nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50017009(CHEMBL19732 | 2-Phenyl-2,5-dihydro-pyrazolo[4,3-c]...)
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50034816(CHEMBL415293 | ZG 63 | 8-Chloro-5-methyl-6-oxo-5,6...)
Affinity DataKi:  9.5nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50049739(DM 286 | CHEMBL58570 | 8-Ethyl-5-methyl-6-oxo-5,6-...)
Affinity DataKi:  10nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM85038(CHEMBL43948 | PZII-029)
Affinity DataKi:  11.6nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM85042(CHEMBL44613 | PW-007A)
Affinity DataKi:  22.5nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM81951(NSC_104999 | CAS_104999 | DMCM)
Affinity DataKi:  38.5nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM26263(ethyl 12-fluoro-8-methyl-9-oxo-2,4,8-triazatricycl...)
Affinity DataKi:  118nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM85041(DM-236 | DM 236)
Affinity DataKi:  188nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM84957(CHEMBL20042 | CGS 9896)
Affinity DataKi:  214nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50243981(CHEMBL453066 | Beta CCM | Methyl Beta-carboline-3 ...)
Affinity DataKi:  436nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM85040(NSC_123700 | CAS_123700 | ZK 91296)
Affinity DataKi:  573nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50244036(CHEMBL509197 | Beta-CCT | tert-butyl 9H-pyrido[3,4...)
Affinity DataKi:  897nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50045050(Allopregnanolone | CHEMBL435035 | 1-(3-Hydroxy-10,...)
Affinity DataKi:  1.90E+3nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM85683(GMA-839 | WAY-141839 | Co-2-6749 | Co 2-6749)
Affinity DataKi:  2.30E+3nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM85039(NSC_121926 | CAS_121926 | ZK 93423)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed