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Report error Found 369 of affinity data for UniProtKB/TrEMBL: P26663
TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235861(US9364482, 36)
Affinity DataIC50: 0.527nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
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TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235890(US9364482, 71)
Affinity DataIC50: 0.782nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
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TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235855(US9364482, 29)
Affinity DataIC50: 0.886nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
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TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235833(US9364482, 7)
Affinity DataIC50: 1.06nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
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TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandPNGBDBM30448(benzothiazine-containing analog, 3a | pyridazin-3-...)
Affinity DataIC50: 10nM EC50:  1.10nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235863(US9364482, 38)
Affinity DataIC50: 1.14nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
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TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandPNGBDBM30466(benzothiazine-containing analog, 4a)
Affinity DataIC50: 10nM EC50:  1.5nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2009
Entry Details Article
PubMed
TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235831(US9364482, 5)
Affinity DataIC50: 1.59nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
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TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235860(US9364482, 35)
Affinity DataIC50: 1.71nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
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TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235845(US9364482, 19)
Affinity DataIC50: 1.75nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
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TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235836(US9364482, 10)
Affinity DataIC50: 1.79nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
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TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235832(US9364482, 6)
Affinity DataIC50: 1.93nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
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TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235839(US9364482, 13)
Affinity DataIC50: 2.06nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
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TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235877(US9364482, 52)
Affinity DataIC50: 2.11nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
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TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235856(US9364482, 30)
Affinity DataIC50: 2.23nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
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TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235887(US9364482, 68)
Affinity DataIC50: 2.24nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
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TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235876(US9364482, 51)
Affinity DataIC50: 2.35nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
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TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235880(US9364482, 55)
Affinity DataIC50: 2.42nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
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TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235827(US9364482, 1)
Affinity DataIC50: 2.44nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
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TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235878(US9364482, 53)
Affinity DataIC50: 2.45nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
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TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235847(US9364482, 21)
Affinity DataIC50: 2.51nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
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TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235850(US9364482, 24)
Affinity DataIC50: 2.57nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
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TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235889(US9364482, 70)
Affinity DataIC50: 2.61nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
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TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235834(US9364482, 8)
Affinity DataIC50: 2.62nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
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TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandPNGBDBM30458(benzothiazine-containing analog, 3b)
Affinity DataIC50: 10nM EC50:  2.70nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2009
Entry Details Article
PubMed
TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235879(US9364482, 54)
Affinity DataIC50: 2.73nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235846(US9364482, 20)
Affinity DataIC50: 2.79nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
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TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235829(US9364482, 3)
Affinity DataIC50: 2.84nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
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TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235884(US9364482, 65)
Affinity DataIC50: 2.95nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235838(US9364482, 12)
Affinity DataIC50: 2.95nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
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TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandPNGBDBM203919(US9242988, 1)
Affinity DataIC50: 3nMpH: 7.3 T: 2°CAssay Description:To measure inhibition of the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase by the nucleoside triphosphate compounds of the present ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2016
Entry Details
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TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235849(US9364482, 23)
Affinity DataIC50: 3.24nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
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TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235828(US9364482, 2)
Affinity DataIC50: 3.34nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
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TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandPNGBDBM30460(benzothiazine-containing analog, 3d)
Affinity DataIC50: 15nM EC50:  3.5nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2009
Entry Details Article
PubMed
TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235883(US9364482, 64)
Affinity DataIC50: 3.63nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235844(US9364482, 18)
Affinity DataIC50: 3.74nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235886(US9364482, 67)
Affinity DataIC50: 3.77nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235835(US9364482, 9)
Affinity DataIC50: 3.91nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235885(US9364482, 66)
Affinity DataIC50: 4.06nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235848(US9364482, 22)
Affinity DataIC50: 4.12nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235854(US9364482, 28)
Affinity DataIC50: 4.17nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
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TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235875(US9364482, 50)
Affinity DataIC50: 4.23nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
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TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandPNGBDBM30415(pyrrolo[1,2-b]pyridazin-2-one analog., 3h)
Affinity DataIC50: 10nM EC50:  5nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandPNGBDBM30407(BMCL185002 Compound 1 | 5-hydroxy- 3(2H)-pyridazin...)
Affinity DataIC50: 10nM EC50:  5nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandPNGBDBM30407(BMCL185002 Compound 1 | 5-hydroxy- 3(2H)-pyridazin...)
Affinity DataIC50: 10nM EC50:  5nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235852(US9364482, 26)
Affinity DataIC50: 5.89nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235873(US9364482, 48)
Affinity DataIC50: 5.97nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
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TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235891(US9364482, 72)
Affinity DataIC50: 6.47nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
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TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235893(US9364482, 74)
Affinity DataIC50: 7.08nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
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TargetGenome polyprotein [1027-1711](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235892(US9364482, 73)
Affinity DataIC50: 7.65nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

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