Compile Data Set for Download or QSAR
Report error Found 124 of affinity data for UniProtKB/TrEMBL: P26431
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50353115(CHEMBL1829127)
Affinity DataIC50: 0.0680nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50353110(CHEMBL1829122)
Affinity DataIC50: 0.0730nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50353113(CHEMBL1829125)
Affinity DataIC50: 0.0840nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50353114(CHEMBL1829126)
Affinity DataIC50: 0.0910nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50353111(CHEMBL1829123)
Affinity DataIC50: 0.110nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50353097(CHEMBL1829132)
Affinity DataIC50: 0.310nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50353116(CHEMBL1829128)
Affinity DataIC50: 0.530nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50353098(CHEMBL1829133)
Affinity DataIC50: 0.560nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50353103(CHEMBL1829139)
Affinity DataIC50: 0.670nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50353102(CHEMBL1829138)
Affinity DataIC50: 0.920nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50378116(CHEMBL1202327)
Affinity DataIC50: 0.940nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50353105(CHEMBL1829117)
Affinity DataIC50: 1.06nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50353099(CHEMBL1829134)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297583(N''-[2-(1H-benzimidazol-2-ylthio)-5-nitro-2,3-dihy...)
Affinity DataIC50: 1.17nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50207580(N-[3-(5-nitro-1H-benzoimidazol-2-yl)-benzoyl]-guan...)
Affinity DataIC50: 1.42nMAssay Description:Inhibition of NHE1 in rat platelets by Platelet swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50353101(CHEMBL1829137)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297577(N''-[2-(1H-benzimidazol-2-ylthio)-2,3-dihydro-1H-i...)
Affinity DataIC50: 1.73nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297571(N''-{2-[(5-nitro-1H-benzimidazol-2-yl)thio]-2,3-di...)
Affinity DataIC50: 1.74nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50345911(CHEMBL1789669 | CHEMBL1783852 | N-(diaminomethylen...)
Affinity DataIC50: 1.82nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297563(N''-[2-(1,3-benzothiazol-2-ylthio)-6-methoxy-2,3-d...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297578(2-{[(1E)-2-(1,3-benzothiazol-2-ylsulfanyl)-4,5,6-t...)
Affinity DataIC50: 1.98nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297580(N''-[2-(1,3-benzothiazol-2-ylthio)-5-chloro-2,3-di...)
Affinity DataIC50: 2.34nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297562(N''-[2-(1,3-benzothiazol-2-ylthio)-5,6-dimethoxy-2...)
Affinity DataIC50: 2.44nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50345911(CHEMBL1789669 | CHEMBL1783852 | N-(diaminomethylen...)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of NHE1-mediated rat platelet swellingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50207583(N-[2-(5-nitro-1H-benzoimidazol-2-yl)-benzoyl]-guan...)
Affinity DataIC50: 4.05nMAssay Description:Inhibition of NHE1 in rat platelets by Platelet swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50345917(N-(diaminomethylene)-3-(N-methylsulfamoyl)-4-(1-(4...)
Affinity DataIC50: 4.48nMAssay Description:Inhibition of NHE1-mediated rat platelet swellingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297575(2-{[(1E)-2-(1H-1,3-benzodiazol-2-ylsulfanyl)-4,5,6...)
Affinity DataIC50: 10.8nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50207572(N-[4-(5-nitro-1H-benzoimidazol-2-yl)-benzoyl]-guan...)
Affinity DataIC50: 11nMAssay Description:Inhibition of NHE1 in rat platelets by Platelet swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50345908(N-(diaminomethylene)-2-((4-(2,3,4-trimethoxybenzyl...)
Affinity DataIC50: 11.1nMAssay Description:Inhibition of NHE1-mediated rat platelet swellingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297576(N''-[2-(1H-benzimidazol-2-ylthio)-5,6-dimethoxy-2,...)
Affinity DataIC50: 11.2nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50345914(N-(diaminomethylene)-3-sulfamoyl-4-((4-(2,3,4-trim...)
Affinity DataIC50: 11.5nMAssay Description:Inhibition of NHE1-mediated rat platelet swellingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297569(N''-{5-chloro-2-[(5-nitro-1H-benzimidazol-2-yl)thi...)
Affinity DataIC50: 12.2nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50115243((S)-N-[7-(5-fluoro-2-methylphenyl)-4-methyl-(7S)-5...)
Affinity DataIC50: 14nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50345912(N-(diaminomethylene)-4-nitro-3-((4-(2,3,4-trimetho...)
Affinity DataIC50: 14.2nMAssay Description:Inhibition of NHE1-mediated rat platelet swellingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50345916(N-(diaminomethylene)-3-(N-methylsulfamoyl)-4-((4-(...)
Affinity DataIC50: 15nMAssay Description:Inhibition of NHE1-mediated rat platelet swellingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297566(N''-{2-[(5-methoxy-1H-benzimidazol-2-yl)thio]-2,3-...)
Affinity DataIC50: 16.8nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50115239((S)-N-[7-(2,5-dichloro-3-thienyl)-4-methyl-(7S)-5,...)
Affinity DataIC50: 17nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50345913(N-(diaminomethylene)-3-nitro-4-(1-(4-(2,3,4-trimet...)
Affinity DataIC50: 18.7nMAssay Description:Inhibition of NHE1-mediated rat platelet swellingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50115246(N-[7-(2-chloro-5-fluorophenyl)-4-methyl-5,6,7,8-te...)
Affinity DataIC50: 19nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50115248(N-[7-(3-chloro-2-thienyl)-4-methyl-5,6,7,8-tetrahy...)
Affinity DataIC50: 19nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50115271(N-[7-(2,5-dichloro-3-thienyl)-4-methyl-5,6,7,8-tet...)
Affinity DataIC50: 19nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50115267(N-[7-(2-chlorophenyl)-4-methyl-(7S)-5,6,7,8-tetrah...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297579(N''-[2-(1,3-benzothiazol-2-ylthio)-4-chloro-2,3-di...)
Affinity DataIC50: 20.3nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297574(N''-[2-(1H-benzimidazol-2-ylthio)-5-chloro-2,3-dih...)
Affinity DataIC50: 21.4nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50115268(N-[7-(2-chloro-3-thienyl)-4-methyl-5,6,7,8-tetrahy...)
Affinity DataIC50: 22nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297564(N''-{6-fluoro-2-[(5-methoxy-1H-benzimidazol-2-yl)t...)
Affinity DataIC50: 25.5nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50115238(N-[7-(2-chlorophenyl)-4-methyl-5,6,7,8-tetrahydro-...)
Affinity DataIC50: 26nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50207574(N-{3-(morpholine-4-sulfonyl)-4-[4-(5-nitro-1H-benz...)
Affinity DataIC50: 27.1nMAssay Description:Inhibition of NHE1 in rat platelets by Platelet swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50207579(N-{3-methanesulfonyl-4-[4-(5-nitro-1H-benzoimidazo...)
Affinity DataIC50: 27.8nMAssay Description:Inhibition of NHE1 in rat platelets by Platelet swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50115245(N-[4-methyl-7-(3-thienyl)-5,6,7,8-tetrahydro-5-qui...)
Affinity DataIC50: 30nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 124 total ) | Next | Last >>
Jump to: