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Report error Found 633 of affinity data for UniProtKB/TrEMBL: P23795
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50342601(Huperzine A | CHEMBL1255901)
Affinity DataKon:  0.000367M-1s-1 Koff:  0.0155s-1Assay Description:Dissociation constant for the inhibition of fetal bovine serum acetylcholinesterase was determined..More data for this Ligand-Target Pair
In DepthDetails Article

TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50027342(CHEMBL483105)
Affinity DataKoff:  1.10E+5s-1Assay Description:Inhibition of bovine AChEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50027343(CHEBI:75701 | ISOPROPYL METHYLPHOSPHONOFLUORIDATE)
Affinity DataKoff:  1.23E+4s-1Assay Description:Inhibition of bovine AChEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50342601(Huperzine A | CHEMBL1255901)
Affinity DataKon:  0.000333M-1s-1Assay Description:Kinetic constant for inhibition of fetal bovine serum acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50093799((R)-1-Amino-13-ethylidene-8,8,11-trimethyl-6-aza-t...)
Affinity DataKoff:  0.0130s-1Assay Description:Kinetic constant for inhibition of fetal bovine serum acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50342601(Huperzine A | CHEMBL1255901)
Affinity DataKoff:  0.0570s-1Assay Description:Kinetic constant for inhibition of fetal bovine serum acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50342601(Huperzine A | CHEMBL1255901)
Affinity DataKoff:  0.0567s-1Assay Description:Kinetic constant for inhibition of fetal bovine serum acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50093799((R)-1-Amino-13-ethylidene-8,8,11-trimethyl-6-aza-t...)
Affinity DataKon:  0.000217M-1s-1Assay Description:Kinetic constant for inhibition of fetal bovine serum acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM9022(N-[5-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino...)
Affinity DataIC50: 0.0200nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM9023(N-{7-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)ami...)
Affinity DataIC50: 0.0600nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50271142(6-Chloro-9-[(3-{4-[(5,6-Dimethoxy-1-oxoindan-2-yl)...)
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of bovine erythrocyte AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50262988(CHEMBL1200541 | N-(2-chlorobenzyl)-2-(2-(2-((2-chl...)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of bovine AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50262879(3-hydroxy-5-(4-(3-hydroxy-5-(trimethylammonio)phen...)
Affinity DataIC50: 0.170nMAssay Description:Inhibition of bovine AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM9009(7-(6-Chloro-1,2,3,4-tetrahydro-acridin-9-ylamino)-...)
Affinity DataIC50: 0.200nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM9035(N-{7-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)ami...)
Affinity DataIC50: 0.200nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM9009(7-(6-Chloro-1,2,3,4-tetrahydro-acridin-9-ylamino)-...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of bovine erythrocyte AchE using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50369748(CHEMBL208599)
Affinity DataIC50: 0.230nMAssay Description:Compound was evaluated for the inhibition of acetylcholinesterase activity from bovine erythrocytes after 30 minutes of incubationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50369748(CHEMBL208599)
Affinity DataIC50: 0.230nMAssay Description:Compound was evaluated for the inhibition of acetylcholinesterase activity from bovine erythrocytes after 30 minutes of incubationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50271140(9-[(3-{4-[(5,6-Dimethoxy-1-oxoindan-2-yl)methyl]pi...)
Affinity DataIC50: 0.290nMAssay Description:Inhibition of bovine erythrocyte AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM9037(N-[5-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino...)
Affinity DataIC50: 0.300nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50262878(3-hydroxy-5-(3-(3-hydroxy-5-(trimethylammonio)phen...)
Affinity DataIC50: 0.490nMAssay Description:Inhibition of bovine AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM9024(N-[8-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino...)
Affinity DataIC50: 0.5nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM9038(N-[6-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino...)
Affinity DataIC50: 0.5nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50094626(rac-huprine H6 | (+)-15-ethyl-7-fluoro-10-azatetra...)
Affinity DataIC50: 0.5nMAssay Description:Compound was evaluated for the inhibition of acetylcholinesterase activity from bovine erythrocytes after 30 minutes of incubationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50271141(6-Chloro-9-[(2-{4-[(5,6-dimethoxy-1-oxoindan-2-yl)...)
Affinity DataIC50: 0.570nMAssay Description:Inhibition of bovine erythrocyte AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM9036(2-(5-bromo-1H-indol-3-yl)-N-{7-[(6-chloro-1,2,3,4-...)
Affinity DataIC50: 0.600nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM10592(7-chloro-15-methyl-10-azatetracyclo[11.3.1.0^{2,11...)
Affinity DataIC50: 0.640nMAssay Description:Compound was evaluated for the inhibition of acetylcholinesterase activity from bovine erythrocytes after 30 minutes of incubationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM10592(7-chloro-15-methyl-10-azatetracyclo[11.3.1.0^{2,11...)
Affinity DataIC50: 0.640nMAssay Description:Compound was evaluated for the inhibition of acetylcholinesterase activity from bovine erythrocytes after 30 minutes of incubationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM9029(N-[6-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino...)
Affinity DataIC50: 0.700nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM9042(2-(1H-indol-3-yl)ethyl N-{6-[(6-chloro-1,2,3,4-tet...)
Affinity DataIC50: 0.700nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50271192(6-Chloro-9-[(3-{4-[(5,6-dimethoxyindan-2-yl)methyl...)
Affinity DataIC50: 0.820nMAssay Description:Inhibition of bovine erythrocyte AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50271190(9-[(3-{4-[(5,6-dimethoxyindan-2-yl)methyl]piperidi...)
Affinity DataIC50: 0.820nMAssay Description:Inhibition of bovine erythrocyte AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM9007(7-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-heptanoic...)
Affinity DataIC50: 1nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50262926(3-(4-(3,4-dimethyl-2-oxo-2H-chromen-7-yloxy)butoxy...)
Affinity DataIC50: 1nMAssay Description:Inhibition of bovine AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM9006(N-[2-(1H-indol-3-yl)ethyl]-6-(1,2,3,4-tetrahydroac...)
Affinity DataIC50: 1nMAssay Description:Inhibition of bovine erythrocyte AchE using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM10592(7-chloro-15-methyl-10-azatetracyclo[11.3.1.0^{2,11...)
Affinity DataIC50: 1.10nMAssay Description:In vitro inhibitory activity against bovine acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM10592(7-chloro-15-methyl-10-azatetracyclo[11.3.1.0^{2,11...)
Affinity DataIC50: 1.15nMAssay Description:Compound was evaluated for the inhibition of acetylcholinesterase of bovine erythrocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50200334((-)-(7S,11S)-huprine H3)
Affinity DataIC50: 1.15nMAssay Description:Inhibition of bovine erythrocyte AChEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50462398(CHEMBL4249848)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of bovine erythrocyte AchE using acetylthiocholine iodide as substrate after 15 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50200343((-)-(7S,11S)-huprine H7)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of bovine erythrocyte AChEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM10597((1S)-7-chloro-15-ethyl-10-azatetracyclo[11.3.1.0^{...)
Affinity DataIC50: 1.30nMAssay Description:In vitro inhibitory activity against bovine acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50462402(CHEMBL4249379)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of bovine erythrocyte AchE using acetylthiocholine iodide as substrate after 15 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM9041(2-(1H-indol-3-yl)ethyl N-{5-[(6-chloro-1,2,3,4-tet...)
Affinity DataIC50: 1.5nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50377921(SODIUM NITROPRUSSIDE)
Affinity DataIC50: 1.74nMAssay Description:Inhibition of bovine erythrocyte AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50271191(6-Chloro-9-[(2-{4-[(5,6-dimethoxyindan-2-yl)methyl...)
Affinity DataIC50: 1.86nMAssay Description:Inhibition of bovine erythrocyte AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50094626(rac-huprine H6 | (+)-15-ethyl-7-fluoro-10-azatetra...)
Affinity DataIC50: 1.91nMAssay Description:Compound was evaluated for the inhibition of acetylcholinesterase activity from bovine erythrocytes after 0 minutes of incubationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM9008(6-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]...)
Affinity DataIC50: 2nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM9012(7-[(6,8-dichloro-1,2,3,4-tetrahydroacridin-9-yl)am...)
Affinity DataIC50: 2nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50262880(3-(3-(3,4-dimethyl-2-oxo-2H-chromen-7-yloxy)propox...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of bovine AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50271189(9-[(2-{4-[(5,6-Dimethoxyindan-2-yl)methyl]piperidi...)
Affinity DataIC50: 2.28nMAssay Description:Inhibition of bovine erythrocyte AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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