Compile Data Set for Download or QSAR
Report error Found 6649 for UniProtKB: P21802
TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM31085(cid_11409972 | 1-[4-[(4-ethylpiperazin-1-yl)methyl...)
Affinity DataKd:  1.90E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM25118(4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-...)
Affinity DataKd:  410nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataKd:  1.40E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM26474(GW-786034 | JMC514632 Compound 13 | 5-({4-[(2,3-di...)
Affinity DataKd:  210nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM6866(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3b ...)
Affinity DataKd:  680nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM31093(cid_11712649 | 4-[[7-[2,6-bis(fluoranyl)phenyl]-9-...)
Affinity DataKd:  1.70E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM31094(PKC-412 | cid_24202429)
Affinity DataKd:  2.40E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  790nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataKd:  2.70E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM31096(CHEMBL290084 | Staurosporine | cid_451705 | US2024...)
Affinity DataKd:  100nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  570nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM13534(VX680 | N-[4-[[4-(4-methylpiperazino)-6-[(5-methyl...)
Affinity DataKd:  570nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM21(VANDETANIB | N-(4-bromo-2-fluorophenyl)-6-methoxy-...)
Affinity DataKd:  1.10E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM81378(FRIN-1)
Affinity DataKd:  5.60nMAssay Description:In vitro kinase assay profiled against a panel of different kinase binding assay using Ambit kinomeScan technology. Biochemical IC50 values were det...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM205483(US9260417, 6)
Affinity DataKd: >1.00E+4nMAssay Description:For the competitive binding assay, test compounds were screened at 10 uM against 70 diverse kinase targets for competitive binding using the KINOMEsc...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM373274(US9902714, Compound 1 | US10421747, Compound 1)
Affinity DataKd:  674nMAssay Description:FGFR2: In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0....More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM373519(US9902714, Compound 2 | US10421747, Compound 2)
Affinity DataKd:  63nMAssay Description:FGFR2: In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0....More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM373520(US9902714, Compound 3 | US10421747, Compound 3)
Affinity DataKd:  620nMAssay Description:FGFR2: In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0....More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM373522(US9902714, Compound 4 | US10421747, Compound 4)
Affinity DataKd:  900nMAssay Description:FGFR2: In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0....More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM373523(US9902714, Compound 6 | US10421747, Compound 6)
Affinity DataKd:  2.90E+3nMAssay Description:FGFR2: In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0....More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM373525(US9902714, Compound 7 | US10421747, Compound 7)
Affinity DataKd:  340nMAssay Description:FGFR2: In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0....More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM373526(US9902714, Compound 9 | US10421747, Compound 9)
Affinity DataKd:  117nMAssay Description:FGFR2: In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0....More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM373274(US9902714, Compound 1 | US10421747, Compound 1)
Affinity DataKd:  674nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technologyMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM373519(US9902714, Compound 2 | US10421747, Compound 2)
Affinity DataKd:  63nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technologyMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM373520(US9902714, Compound 3 | US10421747, Compound 3)
Affinity DataKd:  620nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technologyMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM373522(US9902714, Compound 4 | US10421747, Compound 4)
Affinity DataKd:  900nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technologyMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM373523(US9902714, Compound 6 | US10421747, Compound 6)
Affinity DataKd:  2.90E+3nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technologyMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM373525(US9902714, Compound 7 | US10421747, Compound 7)
Affinity DataKd:  340nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technologyMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM373526(US9902714, Compound 9 | US10421747, Compound 9)
Affinity DataKd:  117nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technologyMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM588098(US11542247, Compound 1)
Affinity DataKd:  1.86E+3nMAssay Description:FGFR2: In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) is incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.0...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM588100(US11542247, Compound 2)
Affinity DataKd: >3.02E+3nMAssay Description:FGFR2: In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) is incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.0...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM588101(US11542247, Compound 3)
Affinity DataKd:  891nMAssay Description:FGFR2: In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) is incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.0...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM588103(US11542247, Compound 4)
Affinity DataKd: >3.02E+3nMAssay Description:FGFR2: In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) is incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.0...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM588104(US11542247, Compound 5)
Affinity DataKd: >3.02E+3nMAssay Description:FGFR2: In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) is incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.0...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM588117(US11542247, Compound 6)
Affinity DataKd: >3.02E+3nMAssay Description:FGFR2: In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) is incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.0...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM588119(US11542247, Compound 7)
Affinity DataKd: >1.00E+3nMAssay Description:FGFR2: In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) is incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.0...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM588120(US11542247, Compound 9)
Affinity DataKd:  933nMAssay Description:FGFR2: In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) is incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.0...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM588121(US11542247, Compound 11)
Affinity DataKd: >3.02E+3nMAssay Description:FGFR2: In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) is incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.0...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM588122(US11542247, Compound 12)
Affinity DataKd:  1.86E+3nMAssay Description:FGFR2: In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) is incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.0...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  660nMAssay Description:Binding constant for FGFR2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  530nMAssay Description:Average Binding Constant for FGFR2; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for FGFR2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM5931(cid_3025986 | CHEMBL296468 | N-(5-{[(5-tert-butyl-...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for FGFR2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM662702(US20240109865, Example 125. | methyl 2-[5-[5-[(1R)...)
Affinity DataKd:  60nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM662747(US20240109865, Example 170. | 5-[(1R)-1-(2,6- dich...)
Affinity DataKd:  60nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM662779(US20240109865, Example 202. | 6-[5-[5-[(1R)-1-(3,5...)
Affinity DataKd:  10nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM662944(US20240109865, Example 378. | 5-[5-[(1R)-1-(3,5-di...)
Affinity DataKd:  60nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM662766(US20240109865, Example 189. | isopropyl 2-[5-[5-[(...)
Affinity DataKd:  10nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM662806(US20240109865, Example 230. | (R)-5-(1-(3,5-dichlo...)
Affinity DataKd:  10nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM31085(cid_11409972 | 1-[4-[(4-ethylpiperazin-1-yl)methyl...)
Affinity DataKd:  1.90E+3nMAssay Description:Binding constant for FGFR2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 6649 total ) | Next | Last >>
Jump to: