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TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098751(Benzo[1,2,5]thiadiazole | CHEMBL283327)
Affinity DataKd:  8.00E+6nMAssay Description:Inhibition of JY-8 cell adhesion via leukocyte function associated antigen 1 (LFA-1) to ICAM-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50094702(CHEMBL15844 | indole | Indole, 7 | Indol | 1H-indo...)
Affinity DataKd:  3.00E+5nMAssay Description:Inhibition of JY-8 cell adhesion via leukocyte function associated antigen 1 (LFA-1) to ICAM-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098763(1-Methyl-1H-indole | CHEMBL19912)
Affinity DataKd:  1.40E+6nMAssay Description:Inhibition of JY-8 cell adhesion via leukocyte function associated antigen 1 (LFA-1) to ICAM-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098766(2,3-Dihydro-benzo[1,4]dioxine | CHEMBL19452)
Affinity DataKd:  1.00E+7nMAssay Description:Inhibition of JY-8 cell adhesion via leukocyte function associated antigen 1 (LFA-1) to ICAM-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154481(Acetic acid 3-[(R)-5-(4-bromo-benzyl)-7-(3,5-dichl...)
Affinity DataKd:  10nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154482(5-(4-Bromo-benzyl)-7-(3,5-dichloro-phenyl)-5-methy...)
Affinity DataKd:  190nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154483((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-5-(...)
Affinity DataKd:  8nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154485(3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-5-metho...)
Affinity DataKd:  360nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154484(3-Benzyl-1-(3,5-dichloro-phenyl)-3-methyl-1,3-dihy...)
Affinity DataKd:  760nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154486(6-(4-Bromo-benzyl)-4-(3,5-dichloro-phenyl)-6-methy...)
Affinity DataKd:  110nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154481(Acetic acid 3-[(R)-5-(4-bromo-benzyl)-7-(3,5-dichl...)
Affinity DataKd:  40nMAssay Description:Dissociation constant against human Lymphocyte function associated antigen1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154487(3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-6-metha...)
Affinity DataKd:  920nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154488((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-3-m...)
Affinity DataKd:  50nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154489((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-3-m...)
Affinity DataKd:  10nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154476((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-5-(...)
Affinity DataKd:  10nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154483((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-5-(...)
Affinity DataKd:  40nMAssay Description:Dissociation constant against human Lymphocyte function associated antigen1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154483((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-5-(...)
Affinity DataKd:  9nMAssay Description:Dissociation constant for human Lymphocyte function-associated antigen-1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154490(3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-3-methy...)
Affinity DataKd:  380nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154493(6-Acetyl-3-(4-bromo-benzyl)-1-(3,5-dichloro-phenyl...)
Affinity DataKd:  1.62E+3nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154491(5-Acetyl-3-(4-bromo-benzyl)-1-(3,5-dichloro-phenyl...)
Affinity DataKd:  240nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154492(N-{3-[(R)-5-(4-Bromo-benzyl)-7-(3,5-dichloro-pheny...)
Affinity DataKd:  30nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154472((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-3-m...)
Affinity DataKd:  300nMAssay Description:Dissociation constant against human Lymphocyte function associated antigen1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154495((S)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-3-m...)
Affinity DataKd: >7.00E+3nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154494((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-5-(...)
Affinity DataKd:  40nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154492(N-{3-[(R)-5-(4-Bromo-benzyl)-7-(3,5-dichloro-pheny...)
Affinity DataKd:  70nMAssay Description:Dissociation constant against human Lymphocyte function associated antigen1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154497(5-(4-Bromo-benzyl)-7-(3,5-dichloro-phenyl)-5-methy...)
Affinity DataKd:  280nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154488((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-3-m...)
Affinity DataKd:  400nMAssay Description:Dissociation constant against human Lymphocyte function associated antigen1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154476((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-5-(...)
Affinity DataKd:  100nMAssay Description:Dissociation constant against human Lymphocyte function associated antigen1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154502(Acetic acid 4-[(R)-5-(4-bromo-benzyl)-7-(3,5-dichl...)
Affinity DataKd:  30nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154498((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-3-m...)
Affinity DataKd:  50nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154505(5-Bromo-3-(4-bromo-benzyl)-1-(3,5-dichloro-phenyl)...)
Affinity DataKd:  180nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154496((R)-5-(4-bromobenzyl)-3-(3,5-dichlorophenyl)-1,5-d...)
Affinity DataKd:  20nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154499(3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-3,5-dim...)
Affinity DataKd:  340nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154501(5-(4-Bromo-benzyl)-7-(3,5-dichloro-phenyl)-5-methy...)
Affinity DataKd:  40nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154476((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-5-(...)
Affinity DataKd:  10nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154506((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-5-(...)
Affinity DataKd:  10nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154500(3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-6-iodo-...)
Affinity DataKd: >2.00E+4nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154477((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-5-m...)
Affinity DataKd:  50nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154503((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-3-m...)
Affinity DataKd:  150nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154504((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-5-(...)
Affinity DataKd:  70nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154473(6-Bromo-3-(4-bromo-benzyl)-1-(3,5-dichloro-phenyl)...)
Affinity DataKd:  630nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154474(3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-5-iodo-...)
Affinity DataKd:  410nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154475(3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-5-metha...)
Affinity DataKd:  70nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154472((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-3-m...)
Affinity DataKd:  10nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154478((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-5-(...)
Affinity DataKd:  20nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154479((R)-5-(3-Amino-propane-1-sulfonyl)-3-(4-bromo-benz...)
Affinity DataKd:  170nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50154480((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-3-m...)
Affinity DataKd:  20nMAssay Description:Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50157352(1-{6-[4-(2-Isopropyl-phenylsulfanyl)-3-trifluorome...)
Affinity DataEC50:  90nMAssay Description:Effective concentration to measure the adherence of LFA-1 expressing JY8 cells to immobilized ICAM-1 in cell-based adhesion assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50157359(4-[4-(2-Isopropyl-phenylsulfanyl)-3-trifluoromethy...)
Affinity DataEC50:  20nMAssay Description:Effective concentration to measure the adherence of LFA-1 expressing JY8 cells to immobilized ICAM-1 in cell-based adhesion assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324825((R)-5-(4-bromobenzyl)-3-(3,5-dichlorophenyl)-5-met...)
Affinity DataKd:  26nMAssay Description:Binding affinity to LFA1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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