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Report error Found 110 of affinity data for UniProtKB/TrEMBL: P17174
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM81461(NSC_3637 | CAS_86-54-4 | Hydralazine | Hydralazine...)
Affinity DataKd:  1.65E+4nMAssay Description:Binding affinity to GOT1 (unknown origin) assessed as dissociation constant by microscale thermophoresis assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50589298(CHEMBL5182428)
Affinity DataIC50: 2.92E+3nMAssay Description:Inhibition of human recombinant GOT1 using aspartic acid and alpha-ketoglutaric acid as substrates incubated in presence of MDH1 and NADHMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50048803(5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-et...)
Affinity DataIC50: 5.39E+3nMAssay Description:Inhibition of GOT1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50589299(CHEMBL5170907)
Affinity DataIC50: 5.91E+3nMAssay Description:Inhibition of C-terminal His6-tagged human recombinant GOT1 expressed in Escherichia coli BL21 (DE3) cells using aspartic acid and alpha-ketoglutaric...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50589293(CHEMBL5203489)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of GOT1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462535(CHEMBL4238792)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462533(CHEMBL4244961)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462466(CHEMBL4237572)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462473(CHEMBL4245427)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462496(CHEMBL4246401)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462524(CHEMBL4239993)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50048280(6-(3-adamantan-1-yl-4-methoxyphenyl)naphthalene-2-...)
Affinity DataIC50: 2.18E+4nMAssay Description:Inhibition of C-terminal His6-tagged human recombinant GOT1 expressed in Escherichia coli BL21 (DE3) cells using aspartic acid and alpha-ketoglutaric...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462528(CHEMBL4249741)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462523(CHEMBL4241742)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM81461(NSC_3637 | CAS_86-54-4 | Hydralazine | Hydralazine...)
Affinity DataIC50: 2.66E+4nMAssay Description:Inhibition of GOT1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM81461(NSC_3637 | CAS_86-54-4 | Hydralazine | Hydralazine...)
Affinity DataIC50: 2.66E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartic acid and alpha-ketoglutaric acid as substrates assessed as reduction in absorbance of NADH incubat...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462553(CHEMBL4246163)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50589296(CHEMBL5176149)
Affinity DataIC50: 2.94E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartic acid and alpha-ketoglutaric acid as substrates assessed as reduction in absorbance of NADH incubat...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462504(CHEMBL4237382)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462554(CHEMBL4239818)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462464(CHEMBL4239817)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462486(CHEMBL4244220)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462502(CHEMBL4248460)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462505(CHEMBL4243647)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462529(CHEMBL4239201)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462546(CHEMBL4241005)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462530(CHEMBL4246252)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462477(CHEMBL4248098)
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50607315(BAY-069)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of GOT1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462468(CHEMBL4249221)
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462469(CHEMBL4243428)
Affinity DataIC50: 5.60E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462481(CHEMBL4239412)
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462503(CHEMBL4244956)
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462485(CHEMBL4237469)
Affinity DataIC50: 6.40E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50589294(CHEMBL5182989)
Affinity DataIC50: 6.54E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartic acid and alpha-ketoglutaric acid as substrates assessed as reduction in absorbance of NADH incubat...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462480(CHEMBL4237444)
Affinity DataIC50: 6.70E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462525(CHEMBL4242135)
Affinity DataIC50: 7.60E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462552(CHEMBL4237925)
Affinity DataIC50: 8.46E+4nMAssay Description:Inhibition of human recombinant GOT1 expressed in Escherichia coli BL21 star DE3 cells using aspartic acid and alpha-ketoglutaric acid as substrates ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462552(CHEMBL4237925)
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462463(CHEMBL4248152)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462465(CHEMBL4240748)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462467(CHEMBL4238388)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50163238(4-Pyridin-4-yl-piperazine-1-carboxylic acid (4-chl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462470(CHEMBL4237836)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462471(CHEMBL4241990)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462472(CHEMBL4237924)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462474(CHEMBL4242890)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462475(CHEMBL4249657)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462476(CHEMBL4244692)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462478(CHEMBL4239952)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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