Compile Data Set for Download or QSAR
Report error Found 68 of affinity data for UniProtKB/TrEMBL: P12785
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189474(7-fluoro-4-hydroxy-6-nitro-3-phenylquinolin-2(1H)-...)
Affinity DataIC50: 50nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50426433(CHEMBL2322360)
Affinity DataIC50: 62nMAssay Description:Inhibition of FASN in rat NMU cells assessed as reduction of de novo synthesis of palmitateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189472(7-chloro-4-hydroxy-6-nitro-3-phenylquinolin-2(1H)-...)
Affinity DataIC50: 73nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189486(3-(4-(benzyloxy)phenyl)-7-chloro-4-hydroxy-6-nitro...)
Affinity DataIC50: 86nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189484(3-biphenyl-4-yl-7-chloro-4-hydroxy-6-nitro-1H-quin...)
Affinity DataIC50: 122nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189470(7-chloro-3-(3,5-dichlorophenyl)-4-hydroxy-6-nitroq...)
Affinity DataIC50: 134nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50426433(CHEMBL2322360)
Affinity DataIC50: 160nMAssay Description:Inhibition of rat FASN assessed as release of co-enzyme AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189475(7-chloro-3-(3,5-difluorophenyl)-4-hydroxy-6-nitroq...)
Affinity DataIC50: 172nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189482(7-chloro-3-(2,4-difluorophenyl)-4-hydroxy-6-nitroq...)
Affinity DataIC50: 173nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50426435(CHEMBL2322370)
Affinity DataIC50: 316nMAssay Description:Inhibition of rat FASN assessed as release of co-enzyme AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50426434(CHEMBL2322359)
Affinity DataIC50: 316nMAssay Description:Inhibition of rat FASN assessed as release of co-enzyme AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50426429(CHEMBL2322364)
Affinity DataIC50: 325nMAssay Description:Inhibition of rat FASN assessed as release of co-enzyme AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50426432(CHEMBL2322361)
Affinity DataIC50: 397nMAssay Description:Inhibition of rat FASN assessed as release of co-enzyme AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189460(7-chloro-3-(2,4-dichlorophenyl)-4-hydroxy-6-nitroq...)
Affinity DataIC50: 443nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50426428(CHEMBL2322365)
Affinity DataIC50: 510nMAssay Description:Inhibition of rat FASN assessed as release of co-enzyme AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189455(4-hydroxy-6-nitro-3-phenylquinolin-2(1H)-one | CHE...)
Affinity DataIC50: 550nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50426443(CHEMBL2322374)
Affinity DataIC50: 635nMAssay Description:Inhibition of rat FASN assessed as release of co-enzyme AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189466(7-chloro-4-hydroxy-6-nitro-3-(thiophen-2-yl)quinol...)
Affinity DataIC50: 700nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267073(2-Undecyl-4-methylene-5-oxo-tetrahydro-thiophene-3...)
Affinity DataIC50: 790nMAssay Description:Inhibition of rat liver FAS by Coomassie blue stainingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267072(2-Decyl-4-methylene-5-oxo-tetrahydro-thiophene-3-c...)
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of rat liver FAS by Coomassie blue stainingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50426446(CHEMBL2322371)
Affinity DataIC50: 1.72E+3nMAssay Description:Inhibition of rat FASN assessed as release of co-enzyme AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267071(2-Nonyl-4-methylene-5-oxo-tetrahydro-thiophene-3-c...)
Affinity DataIC50: 2.28E+3nMAssay Description:Inhibition of rat liver FAS by Coomassie blue stainingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50426431(CHEMBL2322362)
Affinity DataIC50: 2.43E+3nMAssay Description:Inhibition of rat FASN assessed as release of co-enzyme AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267033(2-Octyl-4-methylene-5-oxo-tetrahydro-thiophene-3-c...)
Affinity DataIC50: 2.56E+3nMAssay Description:Inhibition of rat liver FAS by Coomassie blue stainingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189458(7-chloro-4-hydroxy-6-nitro-3-(1H-tetrazol-5-yl)qui...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50426445(CHEMBL2322372)
Affinity DataIC50: 2.95E+3nMAssay Description:Inhibition of rat FASN assessed as release of co-enzyme AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189477(4-hydroxy-8-nitro-3-phenylquinolin-2(1H)-one | CHE...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50426436(CHEMBL2322369)
Affinity DataIC50: 3.07E+3nMAssay Description:Inhibition of rat FASN assessed as release of co-enzyme AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189492(7-chloro-4-hydroxy-3-(3-methylisoxazol-5-yl)-6-nit...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256179((trans)-1-oxo-3-undecylisothiochroman-4-carboxylic...)
Affinity DataIC50: 3.62E+3nMAssay Description:Inhibition of Sprague-Dawley rat liver fatty acid synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50426437(CHEMBL2322368)
Affinity DataIC50: 3.84E+3nMAssay Description:Inhibition of rat FASN assessed as release of co-enzyme AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50426430(CHEMBL2322363)
Affinity DataIC50: 3.85E+3nMAssay Description:Inhibition of rat FASN assessed as release of co-enzyme AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50426427(CHEMBL2322357)
Affinity DataIC50: 3.97E+3nMAssay Description:Inhibition of rat FASN assessed as release of co-enzyme AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256178((trans)-3-decyl-1-oxoisothiochroman-4-carboxylic a...)
Affinity DataIC50: 4.11E+3nMAssay Description:Inhibition of Sprague-Dawley rat liver fatty acid synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189489(7-chloro-4-hydroxy-3-(naphthalen-2-yl)-6-nitroquin...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256132((trans)-3-nonyl-1-oxoisothiochroman-4-carboxylic a...)
Affinity DataIC50: 8.29E+3nMAssay Description:Inhibition of Sprague-Dawley rat liver fatty acid synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256131((trans)-3-octyl-1-oxoisothiochroman-4-carboxylic a...)
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of Sprague-Dawley rat liver fatty acid synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189461(4-hydroxy-6-(methylsulfonyl)-3-phenylquinolin-2(1H...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189467(4-hydroxy-6-nitroquinolin-2(1H)-one | CHEMBL377915)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189468(4-hydroxy-3-phenyl-6-(trifluoromethyl)quinolin-2(1...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189469(4-hydroxy-2-oxo-3-phenyl-1,2-dihydroquinoline-6-ca...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50189487(4-hydroxy-3-phenyl-6-(trifluoromethylsulfonyl)quin...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50001260(4-hydroxy-3-phenylquinolin-2(1H)-one | 3-phenyl-4-...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256128((trans)-4-methylene-2-octyl-5-oxotetrahydrofuran-3...)
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of rat liver FAS by Coomassie blue stainingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256128((trans)-4-methylene-2-octyl-5-oxotetrahydrofuran-3...)
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of Sprague-Dawley rat liver fatty acid synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267032(2-Hexyl-4-methylene-5-oxo-tetrahydro-thiophene-3-c...)
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of rat liver FAS by Coomassie blue stainingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267147(trans-3-Undecyl-1-oxo-isochroman-4-carboxylic acid...)
Affinity DataIC50: 1.95E+4nMAssay Description:Inhibition of rat liver FAS by Coomassie blue stainingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267146(trans-3-Decyl-1-oxo-isochroman-4-carboxylic acid |...)
Affinity DataIC50: 2.42E+4nMAssay Description:Inhibition of rat liver FAS by Coomassie blue stainingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256130((trans)-3-heptyl-1-oxoisothiochroman-4-carboxylic ...)
Affinity DataIC50: 2.69E+4nMAssay Description:Inhibition of Sprague-Dawley rat liver fatty acid synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267103(trans-4-Isopropylidene-2-undecyl-5-oxo-tetrahydrof...)
Affinity DataIC50: 2.75E+4nMAssay Description:Inhibition of rat liver FAS by Coomassie blue stainingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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