Compile Data Set for Download or QSAR
Report error Found 3411 of affinity data for UniProtKB/TrEMBL: P11511
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM19461(5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1...)
Affinity DataKi:  0.00110nM IC50: 1.00E+3nMAssay Description:Inhibition assay using aromatase enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM92556(Neoflavonoid, 8)
Affinity DataKi:  0.00182nM IC50: 1.21E+4nMAssay Description:Inhibition assay using aromatase enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM92555(Neoflavonoid, 7)
Affinity DataKi:  0.00216nMAssay Description:Inhibition assay using aromatase enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM92557(Neoflavonoid, 9)
Affinity DataKi:  0.00256nMAssay Description:Inhibition assay using aromatase enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM8611(CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...)
Affinity DataIC50: 0.00400nMAssay Description:Inhibition of aromatase (unknown origin) transfected in human MCF7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM92559(Neoflavonoid, 11)
Affinity DataKi:  0.00425nMAssay Description:Inhibition assay using aromatase enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM92560(Neoflavonoid, 19)
Affinity DataKi:  0.00597nMAssay Description:Inhibition assay using aromatase enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM92558(Neoflavonoid, 10)
Affinity DataKi:  0.00838nMAssay Description:Inhibition assay using aromatase enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM50539777(CHEMBL4632445)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of aromatase in human JEG-3 cells using Androst-4-ene-3,17-dione as substrate incubated for 1 hr and measured by BCA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM50539776(CHEMBL4639677)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of aromatase in human JEG-3 cells using Androst-4-ene-3,17-dione as substrate incubated for 1 hr and measured by BCA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM92561(Neoflavonoid, 20)
Affinity DataKi:  0.0118nMAssay Description:Inhibition assay using aromatase enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM50337121(2-chloro-4-(((6-cyanobiphenyl-3-yl)(4H-1,2,4-triaz...)
Affinity DataIC50: 0.0150nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM50337123(4-(((6-cyano-4'-methoxybiphenyl-3-yl)(4H-1,2,4-tri...)
Affinity DataIC50: 0.0150nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM50337122(2-bromo-4-(((6-cyanobiphenyl-3-yl)(4H-1,2,4-triazo...)
Affinity DataIC50: 0.0180nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM13061(CHEMBL1444 | 4-[(4-cyanophenyl)(1H-1,2,4-triazol-1...)
Affinity DataKi:  0.0200nMAssay Description:Competitive inhibition of human aromatase using dibenzylfluorescein substrate after 10 mins preincubation measured every 10 sec for 5 mins by Michael...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM8611(CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...)
Affinity DataIC50: 0.0300nMAssay Description:In vitro inhibition of estrogen production in hamster ovarian tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM50337118(5'-((4-bromobenzyl)(4H-1,2,4-triazol-4-yl)amino)-2...)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM8611(CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...)
Affinity DataKi:  0.0500nMAssay Description:Competitive inhibition of human aromatase using dibenzylfluorescein substrate after 10 mins preincubation measured every 10 sec for 5 mins by Michael...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM50366125(CHEMBL1957214)
Affinity DataKi:  0.0600nMAssay Description:Competitive inhibition of human aromatase using dibenzylfluorescein substrate after 10 mins preincubation measured every 10 sec for 5 mins by Michael...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM50592781(CHEMBL5203413)
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of aromatase in human JEG-3 cells using Androst-4-ene-3,17-dione as substrate incubated for 1 hr and measured by BCA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM50307918(2-(5-((1H-1,2,4-triazol-1-yl)methyl)-3'-chloro-4'-...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of aromatase in human JEG3 cells by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM50337117(5'-(benzyl(4H-1,2,4-triazol-4-yl)amino)-2'-cyanobi...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM50123025(CHEMBL3623231)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione as substrate after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM10007(4-[6-Methoxybenzofuran-2-yl)-1H-1,2,4-triazol-1-yl...)
Affinity DataIC50: 0.110nMAssay Description:Inhibition of aromatase in human JEG-3 cells using Androst-4-ene-3,17-dione as substrate incubated for 1 hr and measured by BCA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM50525257(CHEMBL4520995)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of human placental microsome aromatase using [1beta,2beta3H]androstenedione as substrate by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM10016(4-{[(4-bromophenyl)methyl](4H-1,2,4-triazol-4-yl)a...)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of aromatase in human placental microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM50307884(3-CHLORO-2'-CYANO-5'-(1H-1,2,4-TRIAZOL-1-YLMETHYL)...)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of aromatase (unknown origin) expressed in JEG-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM10015(NSC719344 | arimidex | 2-[3-(1-cyano-1-methylethyl...)
Affinity DataKi:  0.130nMAssay Description:Competitive inhibition of human aromatase using dibenzylfluorescein substrate after 10 mins preincubation measured every 10 sec for 5 mins by Michael...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM50307901(5-((1H-1,2,4-triazol-1-yl)methyl)-3'-chloro-4'-hyd...)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of aromatase in human JEG3 cells by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM50337120(4-(((6-cyanobiphenyl-3-yl)(4H-1,2,4-triazol-4-yl)a...)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM10004(1-[(4-fluorophenyl)(6-methoxy-1-benzofuran-2-yl)me...)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of aromatase in human JEG-3 cells using Androst-4-ene-3,17-dione as substrate incubated for 1 hr and measured by BCA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM50307901(5-((1H-1,2,4-triazol-1-yl)methyl)-3'-chloro-4'-hyd...)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of aromatase (unknown origin) expressed in JEG-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM50240798(CHEMBL132530 | 4-hyroxyandrostenedione | (8R,9S,10...)
Affinity DataKi:  0.160nMAssay Description:Binding affinity to aromatase (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM24341(4-{[(4-chloro-3-hydroxyphenyl)methyl](4H-1,2,4-tri...)
Affinity DataIC50: 0.180nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM50307899(5-((1H-1,2,4-triazol-1-yl)methyl)biphenyl-2-carbon...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of aromatase in human JEG3 cells by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM50307900(5-((1H-1,2,4-triazol-1-yl)methyl)-4'-hydroxybiphen...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of aromatase in human JEG3 cells by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM50123026(CHEMBL3623232)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione as substrate after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM50525260(CHEMBL4465348)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM50123026(CHEMBL3623232)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of aromatase in human JEG3 cells using [1beta-3H] androstenedione as substrate assessed as tritiated H2O release after 1 hr by scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM50337119(4-(((6-cyanobiphenyl-3-yl)(4H-1,2,4-triazol-4-yl)a...)
Affinity DataIC50: 0.210nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM50307902(5-((1H-1,2,4-triazol-1-yl)methyl)-4'-chloro-3'-hyd...)
Affinity DataIC50: 0.220nMAssay Description:Inhibition of aromatase in human JEG3 cells by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM50307919(5-((1H-1,2,4-triazol-1-yl)methyl)-3'-chlorobipheny...)
Affinity DataIC50: 0.220nMAssay Description:Inhibition of aromatase in human JEG3 cells by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM50121079(CHEMBL3622064)
Affinity DataIC50: 0.25nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM50121079(CHEMBL3622064)
Affinity DataIC50: 0.25nMAssay Description:Inhibition of aromatase (unknown origin) expressed in JEG-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM50121079(CHEMBL3622064)
Affinity DataIC50: 0.25nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM50121105(CHEMBL3622055)
Affinity DataIC50: 0.260nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM50121105(CHEMBL3622055)
Affinity DataIC50: 0.260nMAssay Description:Inhibition of aromatase (unknown origin) expressed in JEG-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM50121095(CHEMBL3622054)
Affinity DataIC50: 0.280nMAssay Description:Inhibition of aromatase (unknown origin) expressed in JEG-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM50307881(3'-((1H-1,2,4-triazol-1-yl)methyl)-3-chloro-5'-(2-...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of aromatase in human JEG3 cells by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Central Institute of Medicinal and Aromatic Plants

LigandPNGBDBM24328(4-{[(4-hydroxy-3-iodophenyl)methyl](4H-1,2,4-triaz...)
Affinity DataIC50: 0.330nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
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