Compile Data Set for Download or QSAR
Report error Found 55 of affinity data for UniProtKB/TrEMBL: P07727
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50304335(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane...)
Affinity DataIC50: 1.07nMAssay Description:Displacement of [3H]strychnine from GlyR high affinity site in Wistar rat spinal cord by scintillation spectrometry in presence of 10 uM glycineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50304334(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-tropane | ...)
Affinity DataIC50: 10.2nMAssay Description:Displacement of [3H]strychnine from GlyR high affinity site in Wistar rat spinal cord by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50304335(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane...)
Affinity DataIC50: 11.5nMAssay Description:Displacement of [3H]strychnine from GlyR high affinity site in Wistar rat spinal cord by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50304335(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane...)
Affinity DataIC50: 33.9nMAssay Description:Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50415201(CHEMBL611364)
Affinity DataIC50: 33.9nMAssay Description:Displacement of [3H]strychnine from GlyR high affinity site in Wistar rat spinal cord by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50415204(CHEMBL596443)
Affinity DataIC50: 41.7nMAssay Description:Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50415205(CHEMBL595797)
Affinity DataIC50: 50.1nMAssay Description:Displacement of [3H]strychnine from GlyR high affinity site in Wistar rat spinal cord by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50415208(CHEMBL608418)
Affinity DataIC50: 58.9nMAssay Description:Displacement of [3H]strychnine from GlyR high affinity site in Wistar rat spinal cord by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50415210(CHEMBL608417)
Affinity DataIC50: 60.3nMAssay Description:Displacement of [3H]strychnine from GlyR high affinity site in Wistar rat spinal cord by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50304335(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane...)
Affinity DataIC50: 70.8nMAssay Description:Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry in presence of 10 uM glycineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50415211(CHEMBL595791)
Affinity DataIC50: 72.4nMAssay Description:Displacement of [3H]strychnine from GlyR high affinity site in Wistar rat spinal cord by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50415206(CHEMBL596257)
Affinity DataIC50: 79.4nMAssay Description:Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50415203(CHEMBL595116)
Affinity DataIC50: 89.1nMAssay Description:Displacement of [3H]strychnine from GlyR high affinity site in Wistar rat spinal cord by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50415209(CHEMBL596237)
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50304335(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane...)
Affinity DataIC50: 126nMAssay Description:Displacement of [3H]strychnine from GlyR low affinity site in Wistar rat spinal cord by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50415202(CHEMBL611365)
Affinity DataIC50: 129nMAssay Description:Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50304335(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane...)
Affinity DataIC50: 135nMAssay Description:Displacement of [3H]strychnine from GlyR low affinity site in Wistar rat spinal cord by scintillation spectrometry in presence of 10 uM glycineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50415200(CHEMBL610170)
Affinity DataIC50: 166nMAssay Description:Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50304333(3alpha-(2'-Indolecarbonyloxy)-nortropane | CHEMBL5...)
Affinity DataIC50: 234nMAssay Description:Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50304334(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-tropane | ...)
Affinity DataIC50: 1.58E+3nMAssay Description:Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50415211(CHEMBL595791)
Affinity DataIC50: 1.91E+3nMAssay Description:Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50415203(CHEMBL595116)
Affinity DataIC50: 1.91E+3nMAssay Description:Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50304334(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-tropane | ...)
Affinity DataIC50: 2.40E+3nMAssay Description:Displacement of [3H]strychnine from GlyR low affinity site in Wistar rat spinal cord by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50415203(CHEMBL595116)
Affinity DataIC50: 4.27E+3nMAssay Description:Displacement of [3H]strychnine from GlyR low affinity site in Wistar rat spinal cord by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50415208(CHEMBL608418)
Affinity DataIC50: 4.27E+3nMAssay Description:Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50415210(CHEMBL608417)
Affinity DataIC50: 4.68E+3nMAssay Description:Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50415211(CHEMBL595791)
Affinity DataIC50: 5.50E+3nMAssay Description:Displacement of [3H]strychnine from GlyR low affinity site in Wistar rat spinal cord by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50415205(CHEMBL595797)
Affinity DataIC50: 5.62E+3nMAssay Description:Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50415207(CHEMBL594193)
Affinity DataIC50: 7.59E+3nMAssay Description:Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50415210(CHEMBL608417)
Affinity DataIC50: 7.94E+3nMAssay Description:Displacement of [3H]strychnine from GlyR low affinity site in Wistar rat spinal cord by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50415205(CHEMBL595797)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]strychnine from GlyR low affinity site in Wistar rat spinal cord by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50415201(CHEMBL611364)
Affinity DataIC50: 1.12E+4nMAssay Description:Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50415201(CHEMBL611364)
Affinity DataIC50: 2.09E+4nMAssay Description:Displacement of [3H]strychnine from GlyR low affinity site in Wistar rat spinal cord by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50415208(CHEMBL608418)
Affinity DataIC50: 2.29E+4nMAssay Description:Displacement of [3H]strychnine from GlyR low affinity site in Wistar rat spinal cord by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50016626(CHEMBL3274623)
Affinity DataIC50: 2.36E+4nMAssay Description:Displacement of [3H]Strychnine from glycine receptor in rat brain synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50016663(CHEMBL3274624)
Affinity DataIC50: 3.10E+4nMAssay Description:Displacement of [3H]Strychnine from glycine receptor in rat brain synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50016664(CHEMBL3274975)
Affinity DataIC50: 6.79E+4nMAssay Description:Displacement of [3H]Strychnine from glycine receptor in rat brain synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50016570(CHEMBL3274977)
Affinity DataIC50: 2.82E+5nMAssay Description:Displacement of [3H]Strychnine from glycine receptor in rat brain synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50016665(CHEMBL3274976)
Affinity DataIC50: 2.95E+5nMAssay Description:Displacement of [3H]Strychnine from glycine receptor in rat brain synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50016624(CHEMBL3274978)
Affinity DataIC50: 1.00E+6nMAssay Description:Displacement of [3H]Strychnine from glycine receptor in rat brain synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50016623(CHEMBL3274622)
Affinity DataIC50: 1.00E+6nMAssay Description:Displacement of [3H]Strychnine from glycine receptor in rat brain synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50016625(CHEMBL3274979)
Affinity DataIC50: 1.00E+6nMAssay Description:Displacement of [3H]Strychnine from glycine receptor in rat brain synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50225707(CHEBI:28973 | Strychnine)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]strychnine from glycine receptor alpha 1 in rat brain synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50232884(CHEMBL4060962)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]strychnine from glycine receptor alpha 1 in rat brain synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50022784(Methyl-(3-phenyl-3-o-tolyloxy-propyl)-amine(tomoxe...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM82071(NSC_62923 | WY-45030 | VENLAFAXINE | CAS_93413-69-...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM84745(DULOXETINE | LY-248686 | CAS_136434-34-9 | LY24868...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM82071(NSC_62923 | WY-45030 | VENLAFAXINE | CAS_93413-69-...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM84745(DULOXETINE | LY-248686 | CAS_136434-34-9 | LY24868...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50133817(BCTC | CHEMBL441472 | N-(4-tert-butylphenyl)-4-(3-...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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