Compile Data Set for Download or QSAR
Report error Found 136 of affinity data for UniProtKB/TrEMBL: P07650
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20079(5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Thymidine phosphorylase from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20079(5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,...)
Affinity DataIC50: 20nMAssay Description:Inhibitory concentration against thymidine phosphorylase of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20079(5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,...)
Affinity DataIC50: 35nMAssay Description:Inhibition of Escherichia coli thymidine phosphorylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20079(5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,...)
Affinity DataIC50: 36nMAssay Description:Inhibition of Escherichia coli Thymidine phosphorylase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50122768(CHEMBL303346 | CHEMBL194335 | 2-Amino-1-(2,6-dioxo...)
Affinity DataIC50: 560nMAssay Description:Inhibitory concentration against thymidine phosphorylase of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50122770(6-amino-5-bromo-1,2,3,4-tetrahydropyrimidine-2,4-d...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of Thymidine phosphorylase from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50122770(6-amino-5-bromo-1,2,3,4-tetrahydropyrimidine-2,4-d...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory concentration against thymidine phosphorylase of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20033(6-(azetidin-1-yl)-5-bromo-1,3-diazinane-2,4-dione ...)
Affinity DataIC50: 2.00E+3nMAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20051(5-bromo-6-[4-(5-bromo-2,6-dioxo-1,2,3,6-tetrahydro...)
Affinity DataIC50: 2.30E+3nMAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50122765(6-(2-Nitro-imidazol-1-ylmethyl)-1H-pyrimidine-2,4-...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibitory concentration against thymidine phosphorylase of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20052(5-bromo-6-({2-[(5-bromo-2,6-dioxo-1,2,3,6-tetrahyd...)
Affinity DataIC50: 2.50E+3nMAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM193765((E)-5-((2-(quinoxalin-2-yl)hydrazono)methyl)benzen...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of Escherichia coli K12 thymidine phosphorylase expressed in Escherichia coli preincubated for 10 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20036(5-bromo-6-(cyclopropylamino)-1,3-diazinane-2,4-dio...)
Affinity DataIC50: 3.50E+3nMAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50274861(CHEMBL4129729)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of Escherichia coli thymidine phosphorylase pretreated for 10 mins followed by substrate addition measured at 10 mins interval for 30 mins...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20030(6-amino-5-chloro-1,3-diazinane-2,4-dione | 6-amino...)
Affinity DataIC50: 4.00E+3nMAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20034(5-bromo-6-hydrazinyl-1,3-diazinane-2,4-dione | ura...)
Affinity DataIC50: 4.30E+3nMAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20047(5-chloro-6-[2-(hydroxymethyl)piperidin-1-yl]-1,3-d...)
Affinity DataIC50: 4.30E+3nMAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20042(5-chloro-6-(pyrrolidin-1-yl)-1,3-diazinane-2,4-dio...)
Affinity DataIC50: 4.40E+3nMAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20032(5-bromo-6-(pyrrolidin-1-yl)-1,3-diazinane-2,4-dion...)
Affinity DataIC50: 5.30E+3nMAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20048(5-chloro-6-[3-(hydroxymethyl)piperidin-1-yl]-1,3-d...)
Affinity DataIC50: 5.40E+3nMAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20039(5-bromo-6-[4-(hydroxymethyl)piperidin-1-yl]-1,3-di...)
Affinity DataIC50: 5.50E+3nMAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20050(5-chloro-6-[4-(2-hydroxyethyl)piperidin-1-yl]-1,3-...)
Affinity DataIC50: 5.50E+3nMAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20040(5-bromo-6-[4-(2-hydroxyethyl)piperidin-1-yl]-1,3-d...)
Affinity DataIC50: 6.10E+3nMAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50274882(CHEMBL4129587)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of Escherichia coli thymidine phosphorylase pretreated for 10 mins followed by substrate addition measured at 10 mins interval for 30 mins...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20037(5-bromo-6-[2-(hydroxymethyl)piperidin-1-yl]-1,3-di...)
Affinity DataIC50: 6.50E+3nMAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20038(5-bromo-6-[3-(hydroxymethyl)piperidin-1-yl]-1,3-di...)
Affinity DataIC50: 6.50E+3nMAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50134399(1,7-Dihydro-pyrrolo[2,3-d]pyrimidine-2,4-dione | 7...)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of Thymidine phosphorylase from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50159217(4-Amino-1-(5-bromo-2,6-dioxo-1,2,3,6-tetrahydro-py...)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibitory concentration against thymidine phosphorylase of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50159222(5-Bromo-6-(4-nitro-imidazol-1-ylmethyl)-1H-pyrimid...)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibitory concentration against thymidine phosphorylase of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50159219(5-Chloro-6-(4-nitro-imidazol-1-ylmethyl)-1H-pyrimi...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibitory concentration against thymidine phosphorylase of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20041(5-chloro-6-(piperidin-1-yl)-1,3-diazinane-2,4-dion...)
Affinity DataIC50: 7.30E+3nMAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50159220(4-Amino-1-(5-chloro-2,6-dioxo-1,2,3,6-tetrahydro-p...)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibitory concentration against thymidine phosphorylase of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20049(5-chloro-6-[4-(hydroxymethyl)piperidin-1-yl]-1,3-d...)
Affinity DataIC50: 7.50E+3nMAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM222044(5'-O-(4''-Bromobenzoyl)-thymidine-3...)
Affinity DataIC50: 7.50E+3nMT: 2°CAssay Description:TP inhibition assay was performed spectrophotometrically in 96-well plate. The method of Bera et al. was followed with slight modifications [Bera et ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20053(5-chloro-6-[4-(5-chloro-2,6-dioxo-1,2,3,6-tetrahyd...)
Affinity DataIC50: 8.70E+3nMAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20031(5-bromo-6-(piperidin-1-yl)-1,3-diazinane-2,4-dione...)
Affinity DataIC50: 9.10E+3nMAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20044(5-chloro-6-hydrazinyl-1,3-diazinane-2,4-dione | ur...)
Affinity DataIC50: 9.10E+3nMAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50274865(CHEMBL4125852)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of Escherichia coli thymidine phosphorylase pretreated for 10 mins followed by substrate addition measured at 10 mins interval for 30 mins...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50274863(CHEMBL4126296)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of Escherichia coli thymidine phosphorylase pretreated for 10 mins followed by substrate addition measured at 10 mins interval for 30 mins...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20046(5-chloro-6-(cyclopropylamino)-1,3-diazinane-2,4-di...)
Affinity DataIC50: 1.01E+4nMAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20045(5-chloro-6-(morpholin-4-yl)-1,3-diazinane-2,4-dion...)
Affinity DataIC50: 1.04E+4nMAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20035(5-bromo-6-(morpholin-4-yl)-1,3-diazinane-2,4-dione...)
Affinity DataIC50: 1.16E+4nMAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50274883(CHEMBL4126143)
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibition of Escherichia coli thymidine phosphorylase pretreated for 10 mins followed by substrate addition measured at 10 mins interval for 30 mins...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50159218(6-(4-Nitro-imidazol-1-ylmethyl)-1H-pyrimidine-2,4-...)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibitory concentration against thymidine phosphorylase of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM20043(6-(azetidin-1-yl)-5-chloro-1,3-diazinane-2,4-dione...)
Affinity DataIC50: 1.40E+4nMAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50495303(CHEMBL3103184)
Affinity DataIC50: 1.44E+4nMAssay Description:Inhibition of Escherichia coli thymidine phosphorylase using thymidine 5' mono phosphate as substrate after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50274866(CHEMBL4127084)
Affinity DataIC50: 1.73E+4nMAssay Description:Inhibition of Escherichia coli thymidine phosphorylase pretreated for 10 mins followed by substrate addition measured at 10 mins interval for 30 mins...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50495302(CHEMBL3103314)
Affinity DataIC50: 1.76E+4nMAssay Description:Inhibition of Escherichia coli thymidine phosphorylase using thymidine 5' mono phosphate as substrate after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM222040(5'-O-(4''-Methylbenzoyl)-thymidine (4))
Affinity DataIC50: 1.85E+4nMT: 2°CAssay Description:TP inhibition assay was performed spectrophotometrically in 96-well plate. The method of Bera et al. was followed with slight modifications [Bera et ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine phosphorylase(Escherichia coli (strain K12))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM222041(5'-O-(4''-Methoxybenzoyl)-thymidine (1...)
Affinity DataIC50: 1.88E+4nMT: 2°CAssay Description:TP inhibition assay was performed spectrophotometrically in 96-well plate. The method of Bera et al. was followed with slight modifications [Bera et ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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