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TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50459539(CHEMBL4206734)
Affinity DataIC50: 1nMAssay Description:Inhibition of trypsin (unknown origin) pre-incubated for 30 mins before N-Boc-FSR-AMC substrate addition and measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50513213(CHEMBL3344303)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of trypsin (unknown origin) using Boc-Val-Pro-Arg-AMC as substrate preincubated with enzyme for 15 mins followed by addition of substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50513215(CHEMBL4561509)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of trypsin (unknown origin) using Boc-Val-Pro-Arg-AMC as substrate preincubated with enzyme for 15 mins followed by addition of substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50513214(CHEMBL4586045)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of trypsin (unknown origin) using Boc-Val-Pro-Arg-AMC as substrate preincubated with enzyme for 15 mins followed by addition of substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50424712(Camostat Mesilate | Foipan | CAMOSTAT)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of trypsin (unknown origin) using Boc-Val-Pro-Arg-AMC as substrate preincubated with enzyme for 15 mins followed by addition of substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50520867(CHEMBL4441346)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of human trypsin preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50520865(CHEMBL4469752)
Affinity DataIC50: 18nMAssay Description:Inhibition of human trypsin preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50513218(CHEMBL4451902)
Affinity DataIC50: 28nMAssay Description:Inhibition of trypsin (unknown origin) using Boc-Val-Pro-Arg-AMC as substrate preincubated with enzyme for 15 mins followed by addition of substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50220841(BMS-262084 | CHEMBL71037)
Affinity DataIC50: 50nMAssay Description:Inhibition of trypsin (unknown origin) using Chromozyme-TRY substrate incubated for 3 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50520866(CHEMBL4469308)
Affinity DataIC50: 54nMAssay Description:Inhibition of human trypsin preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50339540(CHEMBL4176792)
Affinity DataIC50: 72nMAssay Description:Inhibition of trypsin (unknown origin) assessed as reduction in conversion of N-benzoyl-L-arginine ethyl ester hydrochloride to N-benzoyl-L-arginine ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50599142(CHEMBL5191296)
Affinity DataIC50: 100nMAssay Description:Inhibition of trypsin (unknown origin) using Nalpha-benzoyl-D/L-arginine-4-nitroanilide hydrochloride as substrate preincubated for 5 mins followed b...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50340632(CHEMBL4173435)
Affinity DataIC50: 150nMAssay Description:Inhibition of trypsin (unknown origin) assessed as reduction in conversion of N-benzoyl-L-arginine ethyl ester hydrochloride to N-benzoyl-L-arginine ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50477459(CHEMBL395638)
Affinity DataIC50: 150nMAssay Description:Inhibition of trypsin by FCS methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50340630(CHEMBL4176442)
Affinity DataIC50: 160nMAssay Description:Inhibition of trypsin (unknown origin) assessed as reduction in conversion of N-benzoyl-L-arginine ethyl ester hydrochloride to N-benzoyl-L-arginine ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50457934(CHEMBL23430)
Affinity DataIC50: 169nMAssay Description:Inhibition of human trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50459529(CHEMBL4208878)
Affinity DataIC50: 180nMAssay Description:Inhibition of trypsin (unknown origin) pre-incubated for 30 mins before N-Boc-FSR-AMC substrate addition and measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50340633(CHEMBL4166165)
Affinity DataIC50: 190nMAssay Description:Inhibition of trypsin (unknown origin) assessed as reduction in conversion of N-benzoyl-L-arginine ethyl ester hydrochloride to N-benzoyl-L-arginine ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50129976(4-{4-Methyl-3-oxo-7-[1-(pyrrolidine-1-carbonyl)-cy...)
Affinity DataIC50: 310nMAssay Description:Inhibition of trypsin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50459515(CHEMBL4216138)
Affinity DataIC50: 330nMAssay Description:Inhibition of trypsin (unknown origin) pre-incubated for 30 mins before N-Boc-FSR-AMC substrate addition and measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50138832(CHEMBL3752907)
Affinity DataIC50: 380nMAssay Description:Inhibition of trypsin (unknown origin) using H-D-Phe-Pip-Arg-pNA as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50459537(CHEMBL4217078)
Affinity DataIC50: 380nMAssay Description:Inhibition of trypsin (unknown origin) pre-incubated for 30 mins before N-Boc-FSR-AMC substrate addition and measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50543718(CHEMBL4634303)
Affinity DataIC50: 410nMAssay Description:Inhibition of trypsin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50543719(CHEMBL4646710)
Affinity DataIC50: 547nMAssay Description:Inhibition of trypsin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50129969(N-{1-[3-(4-Carbamimidoyl-benzyl)-1-methyl-2-oxo-1,...)
Affinity DataIC50: 550nMAssay Description:Inhibition of trypsin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50213272(CHEBI:6426 | Leupeptin)
Affinity DataIC50: 600nMAssay Description:Inhibition of trypsin (unknown origin) using Nalpha-benzoyl-D/L-arginine-4-nitroanilide hydrochloride as substrate preincubated for 5 mins followed b...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50477460(CHEMBL395856)
Affinity DataIC50: 650nMAssay Description:Inhibition of trypsin by FCS methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50491950(CHEMBL2386692)
Affinity DataIC50: 821nMAssay Description:Inhibition of trypsin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50491950(CHEMBL2386692)
Affinity DataIC50: 821nMAssay Description:Inhibition of trypsin (unknown origin) using benzoyl-L-arginine-p-nitroanilide hydrochloride as substrate preincubated for 5 mins before substrate ad...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50543714(CHEMBL4640835)
Affinity DataIC50: 824nMAssay Description:Inhibition of trypsin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50138834(CHEMBL3752299)
Affinity DataIC50: 860nMAssay Description:Inhibition of trypsin (unknown origin) using H-D-Phe-Pip-Arg-pNA as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50138888(CHEMBL3752600)
Affinity DataIC50: 930nMAssay Description:Inhibition of trypsin (unknown origin) using H-D-Phe-Pip-Arg-pNA as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50138838(CHEMBL3752312)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of trypsin (unknown origin) using H-D-Phe-Pip-Arg-pNA as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50340631(CHEMBL4162725)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of trypsin (unknown origin) assessed as reduction in conversion of N-benzoyl-L-arginine ethyl ester hydrochloride to N-benzoyl-L-arginine ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50477458(CHEMBL239566)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of trypsin by FCS methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50138837(CHEMBL3753862)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of trypsin (unknown origin) using H-D-Phe-Pip-Arg-pNA as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50322033(2-Methylisoindole-1,3-dione-5-yl 3-(6-aminopyridin...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of trypsin (unknown origin) using Bz-Arg-pNA.HCl as substrate after 5 mins by colorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50138126(CHEMBL3752458)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of trypsin (unknown origin) using H-D-Phe-Pip-Arg-pNA as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1/Trypsin-2(Human)
Collegeville

Curated by ChEMBL
LigandPNGBDBM50062693(Acetic acid (E)-3-[(biphenyl-4-carbonyl)-amino]-2-...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory activity against bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50138893(CHEMBL3752964)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of trypsin (unknown origin) using H-D-Phe-Pip-Arg-pNA as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50513779(CHEMBL4441556)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of trypsin (unknown origin) using Z-FR-MCA as substrate by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1/Trypsin-2(Human)
Collegeville

Curated by ChEMBL
LigandPNGBDBM50062698((E)-2-(3-Carbamimidoyl-benzyl)-3-[(2'-methoxy-biph...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibitory activity against bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1/Trypsin-2(Human)
Collegeville

Curated by ChEMBL
LigandPNGBDBM50062709((E)-2-(3-Carbamimidoyl-benzyl)-3-[(2'-ethoxy-biphe...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibitory activity against bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50138892(CHEMBL3753685)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of trypsin (unknown origin) using H-D-Phe-Pip-Arg-pNA as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50543720(CHEMBL4646911)
Affinity DataIC50: 2.02E+3nMAssay Description:Inhibition of trypsin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50138835(CHEMBL3752269)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of trypsin (unknown origin) using H-D-Phe-Pip-Arg-pNA as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50505096(CHEMBL4436637)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of trypsin (unknown origin) assessed as reduction in enzyme activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1/Trypsin-2(Human)
Collegeville

Curated by ChEMBL
LigandPNGBDBM50062712((E)-2-(3-Carbamimidoyl-benzyl)-3-[(3'-methoxy-biph...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibitory activity against bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50138831(CHEMBL3753071)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of trypsin (unknown origin) using H-D-Phe-Pip-Arg-pNA as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50505092(CHEMBL4475417)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of trypsin (unknown origin) assessed as reduction in enzyme activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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