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TargetSerine protease 1(Human)TBA
LigandPNGBDBM50212459(CHEMBL1159958)
Affinity DataKon:  0.0000330M-1s-1Assay Description:Rate constant of deacylation for trypsinMore data for this Ligand-Target Pair
In DepthDetails

TargetSerine protease 1(Human)TBA
LigandPNGBDBM50212461(CHEMBL1159957)
Affinity DataKon:  0.000333M-1s-1Assay Description:Rate constant of deacylation for trypsinMore data for this Ligand-Target Pair
In DepthDetails

TargetSerine protease 1(Human)TBA
LigandPNGBDBM50212463(CHEMBL1159918)
Affinity DataKon:  0.0000250M-1s-1Assay Description:Rate constant of deacylation for trypsin; Fast and could not be measuredMore data for this Ligand-Target Pair
In DepthDetails

TargetSerine protease 1(Human)TBA
LigandPNGBDBM50212460(CHEMBL1159951)
Affinity DataKon:  0.0000830M-1s-1Assay Description:Rate constant of deacylation for trypsinMore data for this Ligand-Target Pair
In DepthDetails

TargetSerine protease 1(Human)TBA
LigandPNGBDBM50473778(CHEMBL92820)
Affinity DataKd:  347nMAssay Description:Binding affinity against trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)TBA
LigandPNGBDBM50113835(Integrase inhibitor, R1{2} | CHEMBL12392 | 4-fluor...)
Affinity DataKd:  4.27E+5nMAssay Description:Binding affinity against trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)TBA
LigandPNGBDBM10758(14C-phenylethylamine | 2-phenylethan-1-amine | CHE...)
Affinity DataKd:  1.10E+7nMAssay Description:Binding affinity against trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)TBA
LigandPNGBDBM50113829(Decarboxylated derivative | C-Cyclohexyl-methylami...)
Affinity DataKd:  1.15E+6nMAssay Description:Binding affinity against trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)TBA
LigandPNGBDBM50113840(4-Phenyl-butylamine | 4-phenylbutylamine | CHEMBL7...)
Affinity DataKd:  2.00E+7nMAssay Description:Binding affinity against trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)TBA
LigandPNGBDBM50038002(Benzamidine (Protonated) | CHEMBL537204 | CHEMBL20...)
Affinity DataKd:  1.82E+4nMAssay Description:Binding affinity against trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)TBA
LigandPNGBDBM50113826(3-phenylpropylamine | 3-Phenyl-propylamine | CHEMB...)
Affinity DataKd:  3.24E+7nMAssay Description:Binding affinity against trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)TBA
LigandPNGBDBM50236898((1S,2R)-(+)-2-phenylcyclopropylamine | trans-2-phe...)
Affinity DataKd:  1.32E+7nMAssay Description:Binding affinity against trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)TBA
LigandPNGBDBM50072292((3S,3aS,6aS)-3-Phenylsulfanyl-hexahydro-cyclopenta...)
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)TBA
LigandPNGBDBM50072285((3R,3aS,6aS)-3-Phenylsulfanyl-hexahydro-cyclopenta...)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)TBA
LigandPNGBDBM193290(US9199927, 1)
Affinity DataIC50: 0.170nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine protease 1(Human)TBA
LigandPNGBDBM193360(US9199927, 71)
Affinity DataIC50: 0.180nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine protease 1(Human)TBA
LigandPNGBDBM193349(US9199927, 108 | US9199927, 60)
Affinity DataIC50: 0.190nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine protease 1(Human)TBA
LigandPNGBDBM193304(US9199927, 15)
Affinity DataIC50: 0.200nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine protease 1(Human)TBA
LigandPNGBDBM193313(US9199927, 24)
Affinity DataIC50: 0.210nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine protease 1(Human)TBA
LigandPNGBDBM193349(US9199927, 108 | US9199927, 60)
Affinity DataIC50: 0.210nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine protease 1(Human)TBA
LigandPNGBDBM193369(US9199927, 80)
Affinity DataIC50: 0.210nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine protease 1(Human)TBA
LigandPNGBDBM193414(US9199927, 96)
Affinity DataIC50: 0.220nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine protease 1(Human)TBA
LigandPNGBDBM193303(US9199927, 14)
Affinity DataIC50: 0.230nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine protease 1(Human)TBA
LigandPNGBDBM193305(US9199927, 16)
Affinity DataIC50: 0.230nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine protease 1(Human)TBA
LigandPNGBDBM193350(US9199927, 61)
Affinity DataIC50: 0.230nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine protease 1(Human)TBA
LigandPNGBDBM193317(US9199927, 28)
Affinity DataIC50: 0.240nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine protease 1(Human)TBA
LigandPNGBDBM193395(US9199927, 113)
Affinity DataIC50: 0.240nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine protease 1(Human)TBA
LigandPNGBDBM193310(US9199927, 21)
Affinity DataIC50: 0.260nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine protease 1(Human)TBA
LigandPNGBDBM193316(US9199927, 27)
Affinity DataIC50: 0.260nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine protease 1(Human)TBA
LigandPNGBDBM193319(US9199927, 30)
Affinity DataIC50: 0.260nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine protease 1(Human)TBA
LigandPNGBDBM193348(US9199927, 59)
Affinity DataIC50: 0.270nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine protease 1(Human)TBA
LigandPNGBDBM193311(US9199927, 22)
Affinity DataIC50: 0.290nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine protease 1(Human)TBA
LigandPNGBDBM193314(US9199927, 25)
Affinity DataIC50: 0.290nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine protease 1(Human)TBA
LigandPNGBDBM193315(US9199927, 26)
Affinity DataIC50: 0.290nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine protease 1(Human)TBA
LigandPNGBDBM193351(US9199927, 62)
Affinity DataIC50: 0.290nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine protease 1(Human)TBA
LigandPNGBDBM193415(US9199927, 102)
Affinity DataIC50: 0.290nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine protease 1(Human)TBA
LigandPNGBDBM193341(US9199927, 52)
Affinity DataIC50: 0.300nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine protease 1(Human)TBA
LigandPNGBDBM193318(US9199927, 29)
Affinity DataIC50: 0.310nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine protease 1(Human)TBA
LigandPNGBDBM193320(US9199927, 31)
Affinity DataIC50: 0.310nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine protease 1(Human)TBA
LigandPNGBDBM193330(US9199927, 41)
Affinity DataIC50: 0.320nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine protease 1(Human)TBA
LigandPNGBDBM193312(US9199927, 23)
Affinity DataIC50: 0.340nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine protease 1(Human)TBA
LigandPNGBDBM193355(US9199927, 66)
Affinity DataIC50: 0.350nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine protease 1(Human)TBA
LigandPNGBDBM193323(US9199927, 34)
Affinity DataIC50: 0.360nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine protease 1(Human)TBA
LigandPNGBDBM193353(US9199927, 64)
Affinity DataIC50: 0.370nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine protease 1(Human)TBA
LigandPNGBDBM193326(US9199927, 37)
Affinity DataIC50: 0.380nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine protease 1(Human)TBA
LigandPNGBDBM193354(US9199927, 65)
Affinity DataIC50: 0.400nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine protease 1(Human)TBA
LigandPNGBDBM193382(US9199927, 93)
Affinity DataIC50: 0.400nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine protease 1(Human)TBA
LigandPNGBDBM193343(US9199927, 54)
Affinity DataIC50: 0.420nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine protease 1(Human)TBA
LigandPNGBDBM193383(US9199927, 94)
Affinity DataIC50: 0.420nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine protease 1(Human)TBA
LigandPNGBDBM193306(US9199927, 17)
Affinity DataIC50: 0.430nMpH: 8.0 T: 2°CAssay Description:The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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