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TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM50304486((3R,4R,5R,6R)-3-acetamido-6-(acetoxymethyl)tetrahy...)
Affinity DataKd:  1.50E+5nMAssay Description:Binding affinity to human recombinant ASGPR1 carbohydrate recognition domain expressed in Escherichia coli AD494 by surface plasmon resonance spectro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM50077229(beta-D-galactopyranose | beta-D-galactose | CHEMBL...)
Affinity DataKd:  1.46E+6nMAssay Description:Binding affinity to human recombinant ASGPR1 carbohydrate recognition domain expressed in Escherichia coli AD494 by surface plasmon resonance spectro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM50304487((2R,3R,4S,5S,6R)-2,3,4,5-tetramethoxy-6-(methoxyme...)
Affinity DataKd:  2.20E+6nMAssay Description:Binding affinity to human recombinant ASGPR1 carbohydrate recognition domain expressed in Escherichia coli AD494 by surface plasmon resonance spectro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM50304488((2S,3R,4S,5S,6R)-2,3,4,5-tetramethoxy-6-(methoxyme...)
Affinity DataKd:  2.76E+6nMAssay Description:Binding affinity to human recombinant ASGPR1 carbohydrate recognition domain expressed in Escherichia coli AD494 by surface plasmon resonance spectro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM50240803(beta-D-glucopyranose | beta-D-glucose | Glucoside ...)
Affinity DataKd: >1.00E+7nMAssay Description:Binding affinity to human recombinant ASGPR1 carbohydrate recognition domain expressed in Escherichia coli AD494 by surface plasmon resonance spectro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM408853(US10376531, Compound 3 | US10813942, Compound 3)
Affinity DataKd:  7.18E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In DepthDetails
US Patent
PDB3D3D Structure (crystal)
TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM408854(US10376531, Compound II-b | US10813942, Compound I...)
Affinity DataKd:  1.99E+5nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM408855(US10376531, Compound 1 | US10813942, Compound 1)
Affinity DataKd:  9.00E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM408856(US10376531, Compound 18 | US10813942, Compound 18)
Affinity DataKd:  3.10E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM408857(US10376531, Compound 17 | US10813942, Compound 17)
Affinity DataKd:  5.30E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM408858(US10376531, Compound 20 | US10813942, Compound 20)
Affinity DataKd:  2.18E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM408859(US10376531, Compound 19 | US10813942, Compound 19)
Affinity DataKd:  3.30E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM408860(US10376531, Compound 21 | US10813942, Compound 21)
Affinity DataKd:  3.40E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM408861(US10376531, Compound 22 | US10813942, Compound 22)
Affinity DataKd:  5.50E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM408862(US10376531, Compound 25 | US10813942, Compound 25)
Affinity DataKd:  2.20E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM408863(US10376531, Compound 24 | US10813942, Compound 24)
Affinity DataKd:  1.10E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM408864(US10376531, Compound 26 | US10813942, Compound 26)
Affinity DataKd:  6.00E+4nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM408865(US10376531, Compound 29 | US10813942, Compound 29)
Affinity DataKd:  6.90E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM408866(US10376531, Compound 30 | US10813942, Compound 30)
Affinity DataKd:  1.10E+5nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM408867(US10376531, Compound 27 | US10813942, Compound 27)
Affinity DataKd:  700nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM408868(US10376531, Compound 28 | US10813942, Compound 28)
Affinity DataKd:  1.20E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM408869(US10376531, Compound 31 | US10813942, Compound 31)
Affinity DataKd:  1.23E+4nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM408853(US10376531, Compound 3 | US10813942, Compound 3)
Affinity DataKd:  7.18E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In DepthDetails
US Patent
PDB3D3D Structure (crystal)
TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM408854(US10376531, Compound II-b | US10813942, Compound I...)
Affinity DataKd:  2.50E+5nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM408855(US10376531, Compound 1 | US10813942, Compound 1)
Affinity DataKd:  9.00E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM408856(US10376531, Compound 18 | US10813942, Compound 18)
Affinity DataKd:  3.00E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM408857(US10376531, Compound 17 | US10813942, Compound 17)
Affinity DataKd:  3.80E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM408858(US10376531, Compound 20 | US10813942, Compound 20)
Affinity DataKd:  3.40E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM408859(US10376531, Compound 19 | US10813942, Compound 19)
Affinity DataKd:  4.70E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM408860(US10376531, Compound 21 | US10813942, Compound 21)
Affinity DataKd:  2.60E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM408861(US10376531, Compound 22 | US10813942, Compound 22)
Affinity DataKd:  6.50E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM408862(US10376531, Compound 25 | US10813942, Compound 25)
Affinity DataKd:  3.10E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM408863(US10376531, Compound 24 | US10813942, Compound 24)
Affinity DataKd:  1.40E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM408864(US10376531, Compound 26 | US10813942, Compound 26)
Affinity DataKd:  1.12E+5nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM408865(US10376531, Compound 29 | US10813942, Compound 29)
Affinity DataKd:  1.02E+4nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM408866(US10376531, Compound 30 | US10813942, Compound 30)
Affinity DataKd:  1.61E+5nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM408867(US10376531, Compound 27 | US10813942, Compound 27)
Affinity DataKd:  1.10E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM408868(US10376531, Compound 28 | US10813942, Compound 28)
Affinity DataKd:  2.00E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM408869(US10376531, Compound 31 | US10813942, Compound 31)
Affinity DataKd:  1.37E+4nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM656113(US20240072809, Compound A90)
Affinity DataKd: <5.00E+5nMAssay Description:The dissociation constants (KD) of compounds described herein to the ASGP receptor are measured in SPR experiments using a Biacore 8K instrument (GE ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM656115(US20240072809, Compound A92)
Affinity DataKd: >1.00E+6nMAssay Description:The dissociation constants (KD) of compounds described herein to the ASGP receptor are measured in SPR experiments using a Biacore 8K instrument (GE ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM656116(US20240072809, Compound A95)
Affinity DataKd: <1.00E+5nMAssay Description:The dissociation constants (KD) of compounds described herein to the ASGP receptor are measured in SPR experiments using a Biacore 8K instrument (GE ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM656120(US20240072809, Compound A99)
Affinity DataKd: >1.00E+6nMAssay Description:The dissociation constants (KD) of compounds described herein to the ASGP receptor are measured in SPR experiments using a Biacore 8K instrument (GE ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM656124(US20240072809, Compound A100)
Affinity DataKd: <1.00E+5nMAssay Description:The dissociation constants (KD) of compounds described herein to the ASGP receptor are measured in SPR experiments using a Biacore 8K instrument (GE ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM656127(US20240072809, Compound A103)
Affinity DataKd: <5.00E+5nMAssay Description:The dissociation constants (KD) of compounds described herein to the ASGP receptor are measured in SPR experiments using a Biacore 8K instrument (GE ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM656131(US20240072809, Compound A105)
Affinity DataKd: <1.00E+5nMAssay Description:The dissociation constants (KD) of compounds described herein to the ASGP receptor are measured in SPR experiments using a Biacore 8K instrument (GE ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM656132(US20240072809, Compound A106)
Affinity DataKd: <1.00E+5nMAssay Description:The dissociation constants (KD) of compounds described herein to the ASGP receptor are measured in SPR experiments using a Biacore 8K instrument (GE ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM656136(US20240072809, Compound A107)
Affinity DataKd: >1.00E+6nMAssay Description:The dissociation constants (KD) of compounds described herein to the ASGP receptor are measured in SPR experiments using a Biacore 8K instrument (GE ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM656141(US20240072809, Compound A108)
Affinity DataKd: <1.00E+5nMAssay Description:The dissociation constants (KD) of compounds described herein to the ASGP receptor are measured in SPR experiments using a Biacore 8K instrument (GE ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAsialoglycoprotein receptor 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM656143(US20240072809, Compound A109)
Affinity DataKd: <1.00E+5nMAssay Description:The dissociation constants (KD) of compounds described herein to the ASGP receptor are measured in SPR experiments using a Biacore 8K instrument (GE ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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